Interesting facts
Interesting Facts about 2-[2-hydroxyethyl-[2-(5-nitro-2-furyl)quinazolin-4-yl]amino]ethanol
This compound, with its complex structure, is a fascinating example of the intersection between medicinal chemistry and organic synthesis. Here are some noteworthy aspects:
- Structural Intricacy: The compound features a quinazoline core, known for its biological significance, particularly in the development of pharmaceuticals. Quinazolines are often explored for their potential as anticancer agents, showcasing how structure can influence biological activity.
- Functional Groups: The presence of a 5-nitro-2-furyl group adds to the compound's aromatic characteristics. This nitro group can enhance the compound's electronic properties, potentially increasing its interactions with biological targets.
- Hydroxyethyl Linkage: The hydroxyethyl component provides the compound with hydrophilicity. This feature can be critical for enhancing solubility and bioavailability in pharmacological applications.
- Potential Applications: Due to its complex functionalities, there is ongoing research into compounds like this for their potential role in treating conditions such as cancer and infectious diseases, illustrating the relationship between compound design and therapeutic efficacy.
- Research and Development: This compound serves as a starting point for synthetic chemists and pharmacologists to explore modifications that could lead to more effective derivatives with improved activity or reduced side effects.
In summary, 2-[2-hydroxyethyl-[2-(5-nitro-2-furyl)quinazolin-4-yl]amino]ethanol exemplifies the rich potential of complex organic molecules in modern medicinal chemistry, inspiring researchers to uncover new horizons in drug discovery.
Synonyms
NIFURQUINAZOL
Nifurquinazole
5055-20-9
NF-1088
NF 1088
NSC-220589
2-[2-hydroxyethyl-[2-(5-nitrofuran-2-yl)quinazolin-4-yl]amino]ethanol
4-Bis(2-hydroxyethyl)amino-2-(5-nitro-2-furyl)quinazoline
2,2'-((2-(5-Nitro-2-furyl)-4-quinazolinyl)imino)diethanol
Quinazoline, 4-bis(2-hydroxyethyl)amino-2-(5-nitro-2-furyl)-
44E5RRL600
NSC220589
Ethanol, 2,2'-((2-(5-nitro-2-furanyl)-4-quinazolinyl)imino)bis-
Nifurquinazolum
Nifurchinazolo
Nifurchinazolo [DCIT]
Nifurquinazol [USAN:INN]
Nifurquinazolum [INN-Latin]
NSC 22058
NSC 220589
BRN 1092044
2,2'-[[2-(5-Nitro-2-furyl)-4-quinazolinyl]imino]diethanol
UNII-44E5RRL600
N-(2-(5-Nitro-2-furyl)-4-chinazolinyl)-2,2-iminodiethanol
NIFURQUINAZOL [INN]
Nifurquinazol (USAN/INN)
NIFURQUINAZOL [USAN]
SCHEMBL193816
CHEMBL2107101
GTPL12344
DTXSID50198582
Ethanol, 2,2'-((2-(5-nitro-2-furyl)-4-quinazolinyl)imino)di-
ZINC00001810
NS00120235
D05164
WLN: T66 BN DNJ EN2Q2Q C- BT5OJ ENW
Q15409366
Ethanol,2'-[[2-(5-nitro-2-furyl)-4-quinazolinyl]imino]di-
Ethanol,2'-[[2-(5-nitro-2-furanyl)-4-quinazolinyl]imino]bis-
2-[2-hydroxyethyl-[2-(5-nitro-2-furyl)quinazolin-4-yl]amino]ethanol
Ethanol, 2,2'-[[2- (5-nitro-2-furanyl)-4-quinazolinyl]imino]bis-
Solubility of 2-[2-hydroxyethyl-[2-(5-nitro-2-furyl)quinazolin-4-yl]amino]ethanol
The solubility of 2-[2-hydroxyethyl-[2-(5-nitro-2-furyl)quinazolin-4-yl]amino]ethanol can be influenced by several factors, including its molecular structure and the presence of functional groups.
Key Aspects of Solubility:
In practical applications, the solubility profile of 2-[2-hydroxyethyl-[2-(5-nitro-2-furyl)quinazolin-4-yl]amino]ethanol would need to be determined through experimental studies, as theoretical predictions may not account for all interactions in real solutions. Understanding its solubility is essential for potential pharmaceutical uses and formulation strategies.