Ibuprofen | Solubility of Things

Identification

Molecular formula

C₁₃H₁₈O₂

CAS number

15687-27-1

IUPAC name

2-[2-isopropyl-1-(2-isopropylphenyl)cyclohexoxy]-N,N-dimethyl-ethanamine

State

Ibuprofen is typically encountered in tablet form at room temperature, indicating a solid state. Pure Ibuprofen itself is a solid at room temperature.

Melting point (Celsius)

75.00

Melting point (Kelvin)

348.15

Boiling point (Celsius)

157.00

Boiling point (Kelvin)

430.15

General information

Molecular weight

206.28g/mol

Molar mass

206.2800g/mol

Density

1.1130g/cm³

Appearence

Ibuprofen appears as a white crystalline solid. It is odorless and is commonly available in granular or powder form often pressed into tablets or used in capsules for pharmaceutical formulations. Its appearance might vary slightly depending on the formulation and any additives used.

Comment on solubility

Solubility of 2-[2-isopropyl-1-(2-isopropylphenyl)cyclohexoxy]-N,N-dimethyl-ethanamine

The compound 2-[2-isopropyl-1-(2-isopropylphenyl)cyclohexoxy]-N,N-dimethyl-ethanamine exhibits unique solubility characteristics that can be intriguing to explore. Solubility is a critical property that determines how a substance interacts with various solvents, particularly water and organic solvents.

For this specific compound, consider the following aspects:

Polarity: The presence of amine (-N,N-dimethyl) functional groups often increases solubility in polar solvents. However, the bulky isopropyl and cyclohexyl groups might hinder this interaction.
Hydrophobicity: Given the large hydrophobic groups, this compound may have reduced solubility in water, making it more favorable for solubility in non-polar organic solvents.
Temperature Dependency: Solubility can also be affected by temperature; higher temperatures generally increase solubility for many organic compounds.
Complex Formation: In certain cases, the ability of the molecule to form complexes with solvents can enhance its solubility.

In summary, while 2-[2-isopropyl-1-(2-isopropylphenyl)cyclohexoxy]-N,N-dimethyl-ethanamine exhibits limited solubility in water due to its hydrophobic characteristics, it is likely to dissolve more readily in non-polar organic solvents. Maintaining an understanding of these solubility dynamics is key in applications ranging from pharmaceuticals to industrial formulations.

Interesting facts

Interesting Facts about 2-[2-isopropyl-1-(2-isopropylphenyl)cyclohexoxy]-N,N-dimethyl-ethanamine

This compound is a fascinating example of synthetic organic chemistry, incorporating various structural elements that contribute to its intriguing properties. Here are a few notable aspects:

Complex Structure: The molecule showcases a complex arrangement featuring multiple functional groups and a cyclohexane structure, which is known for its stability and unique conformational dynamics.
Pharmacological Significance: Compounds of this nature are often studied for their potential applications in pharmaceuticals, particularly in relation to their interaction with biological targets, such as receptors in the nervous system.
Chirality Impact: The presence of isopropyl groups and their specific arrangement may introduce chirality, which plays a critical role in determining the biological activity of the compound, as different enantiomers can exhibit markedly different effects.
Research Applications: Due to its structural complexity, this compound can serve as a model for exploring synthetic routes, mechanisms of action, or even as a lead compound for drug development.
Synthetic Challenges: The synthesis of such compounds presents challenges to chemists, requiring advanced techniques in organic synthesis and a deep understanding of reaction mechanisms.

In exploring this compound, one is reminded of the quote by famous chemist Linus Pauling: "The best way to have a good idea is to have a lot of ideas." The intricate nature of 2-[2-isopropyl-1-(2-isopropylphenyl)cyclohexoxy]-N,N-dimethyl-ethanamine provides a rich platform for innovation and discovery in chemical research.