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2-(2-methoxyanilino)acetonitrile

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Identification
Molecular formula
C9H10N2O
CAS number
7458-35-9
IUPAC name
2-(2-methoxyanilino)acetonitrile
State
State

At room temperature, 2-(2-methoxyanilino)acetonitrile exists as a solid. This characteristic makes it relatively stable and easy to handle in typical environmental conditions.

Melting point (Celsius)
54.00
Melting point (Kelvin)
327.10
Boiling point (Celsius)
306.50
Boiling point (Kelvin)
579.60
General information
Molecular weight
162.19g/mol
Molar mass
162.1870g/mol
Density
1.1117g/cm3
Appearence

2-(2-Methoxyanilino)acetonitrile is typically observed as a white to off-white crystalline solid. Its appearance can vary slightly depending on purity and specific synthesis conditions.

Comment on solubility

Solubility of 2-(2-methoxyanilino)acetonitrile

The solubility of 2-(2-methoxyanilino)acetonitrile is influenced by several key factors, including its chemical structure and the solvent used. This compound is classified as a polar molecule due to the presence of both the methoxy group and the acetonitrile moiety, which enhances its ability to interact with polar solvents, such as:

  • Water
  • Methanol
  • Ethanol

Generally, polar compounds tend to dissolve well in polar solvents, and it is likely that 2-(2-methoxyanilino)acetonitrile exhibits good solubility in these environments. However, certain organic solvents may also accommodate this compound, albeit to a lesser extent, thus:

  • It may show moderate solubility in less polar solvents.
  • Its solubility could significantly decrease in non-polar solvents.

As a general rule, the degree of solubility can also depend on temperature, with higher temperatures usually promoting better solubility for many chemical compounds. As stated, "Temperature effects on solubility can vary significantly based on the interactions between solute and solvent." Thus, when working with 2-(2-methoxyanilino)acetonitrile, it is essential to consider the solvent system, desired concentrations, and specific conditions to accurately predict its solubility profile.

Interesting facts

Interesting Facts about 2-(2-Methoxyanilino)acetonitrile

2-(2-Methoxyanilino)acetonitrile is a fascinating compound that plays a significant role in various chemical reactions and syntheses. Here are some intriguing aspects of this compound:

  • Structural Characteristics: This compound features a unique structure that includes a methoxy group attached to an aniline derivative. The presence of the acetonitrile functional group further enhances its chemical reactivity.
  • Applications in Synthesis: 2-(2-Methoxyanilino)acetonitrile serves as an important building block in organic synthesis, particularly in the creation of pharmaceuticals and agrochemicals. Its ability to act as a nucleophile opens up possibilities for various substitution and coupling reactions.
  • Biological Activity: Compounds similar to 2-(2-Methoxyanilino)acetonitrile have been investigated for their biological properties. Such derivatives may display potential activity against specific types of cancer or other diseases, making them candidates for further research in medicinal chemistry.
  • Research Opportunities: Due to its interesting chemical properties, this compound offers significant opportunities for research in fields like synthetic organic chemistry and pharmaceutical development. Students and researchers can explore its reactivity and potential applications extensively.
  • Safety Considerations: As with any chemical compound, it is essential to handle 2-(2-Methoxyanilino)acetonitrile with care. Understanding its toxicity and safe handling procedures is crucial in laboratory settings.

In summary, 2-(2-Methoxyanilino)acetonitrile exemplifies the versatility and utility of organic compounds in research and applications. The study of its properties and reactions not only enhances our understanding of organic chemistry but also paves the way for innovations in pharmaceuticals and beyond.

Synonyms
ACETONITRILE, o-ANISIDINO-
28354-25-8
O-Anisidino-Acetonitrile
P6O8BG8HGN
NSC 406187
BRN 2719761
Acetonitrile, ((2-methoxyphenyl)amino)-
AI3-02824
UNII-P6O8BG8HGN
NSC-406187
2-((2-methoxyphenyl)amino)acetonitrile
DTXSID20182599
4-13-00-00856 (Beilstein Handbook Reference)
ACETONITRILE, 2-((2-METHOXYPHENYL)AMINO)-
RefChem:202355
DTXCID10105090
O-Anisidinoacetonitrile
2-(2-methoxyanilino)acetonitrile
NSC406187
SCHEMBL4267637
(2-methoxy-phenylamino)-acetonitrile
SBB081919
AKOS000252699
2-[(2-methoxyphenyl)amino]ethanenitrile