Skip to main content

Lobeline hydrochloride

ADVERTISEMENT
Identification
Molecular formula
C19H24Cl2N2
CAS number
134-63-4
IUPAC name
[2-[(2-methyl-1,2,3,4-tetrahydroisoquinolin-2-ium-1-yl)methyl]phenyl]ammonium;dichloride
State
State

At room temperature, Lobeline hydrochloride is typically in a solid state, appearing as a white or off-white crystalline substance.

Melting point (Celsius)
156.00
Melting point (Kelvin)
429.00
Boiling point (Celsius)
250.00
Boiling point (Kelvin)
523.00
General information
Molecular weight
368.32g/mol
Molar mass
368.3210g/mol
Density
1.2500g/cm3
Appearence

Lobeline hydrochloride generally appears as a white or off-white crystalline powder. It is highly soluble in water, imparting a clear solution.

Comment on solubility

Solubility of [2-[(2-methyl-1,2,3,4-tetrahydroisoquinolin-2-ium-1-yl)methyl]phenyl]ammonium;dichloride

The solubility of the compound [2-[(2-methyl-1,2,3,4-tetrahydroisoquinolin-2-ium-1-yl)methyl]phenyl]ammonium;dichloride can be characterized based on various factors:

  • Ionic Nature: As a dichloride salt, it is expected to be soluble in polar solvents due to the presence of ionic interactions.
  • Polarity: The compound's structure incorporates both hydrophilic (ionic ammonium) and hydrophobic components, which can influence solubility in organic and aqueous solutions.
  • Temperature Effects: Increased temperature often enhances solubility for ionic compounds, which could make this compound more soluble in heated polar solvents.
  • pH Influence: The solubility can also vary with changes in pH, as protonation and deprotonation can affect the ionic character of the compound.

Generally, one can consider the solubility behavior to reflect the interactions between solvent molecules and the ionic species present in the compound. In practical terms, this compound is likely soluble in water and other polar solvents but may face reduced solubility in non-polar media due to the hydrophobic nature of the isoquinoline moiety. It is always advisable to conduct solubility tests in the target solvent for precise evaluations.

Interesting facts

Interesting Facts about 2-[(2-methyl-1,2,3,4-tetrahydroisoquinolin-2-ium-1-yl)methyl]phenyl]ammonium Dichloride

This compound, commonly referred to as a member of the quaternary ammonium salts, showcases fascinating properties that spark interest in various scientific disciplines. Here are several noteworthy aspects:

  • Structural Complexity: The compound consists of a tetrahydroisoquinoline core, which contributes to its unique structural characteristics. Isoquinolines are known for their significant role in medicinal chemistry.
  • Cationic Nature: As a quaternary ammonium compound, it carries a positive charge, making it hydrophilic. This property is essential for interactions with biological membranes and potential applications in therapeutic delivery.
  • Pharmaceutical Applications: Quaternary ammonium compounds like this one are often explored for their antibacterial and antiviral properties. They can function as antimicrobial agents due to their ability to disrupt microbial cell membranes.
  • Research Interest: The tetrahydroisoquinoline structure has been researched due to its potential anti-cancer and neuroprotective effects. Compounds derived from this structure are often investigated in the development of new pharmacological agents.
  • Versatile Reactions: This compound can participate in a variety of chemical reactions, making it useful in organic synthesis. Its nitrogen and carbon positions allow for functionalization, leading to derivatives with tailored properties.

In summary, 2-[(2-methyl-1,2,3,4-tetrahydroisoquinolin-2-ium-1-yl)methyl]phenyl]ammonium dichloride is more than a complex chemical formula; it embodies exciting potentials in medicinal chemistry and synthetic organic chemistry. Its unique structural features and biological activities continue to inspire research, rendering it a fascinating subject for students and scientists alike.

Synonyms
1-(o-Aminobenzyl)-2-methyl-1,2,3,4-tetrahydroisoquinoline dihydrochloride
17750-48-0
ISOQUINOLINE, 1,2,3,4-TETRAHYDRO-1-(o-AMINOBENZYL)-2-METHYL-, DIHYDROCHLORIDE