Skip to main content

Oxymetazoline

ADVERTISEMENT
Identification
Molecular formula
C16H24N2O
CAS number
1491-59-4
IUPAC name
2-[(2-methylbenzothiophen-3-yl)methyl]-4,5-dihydro-1H-imidazole
State
State

Oxymetazoline is typically in a solid state at room temperature and is provided in various application forms, including liquids, when compounded for medical use in decongestant formulations.

Melting point (Celsius)
136.00
Melting point (Kelvin)
409.15
Boiling point (Celsius)
362.00
Boiling point (Kelvin)
635.15
General information
Molecular weight
260.35g/mol
Molar mass
260.3540g/mol
Density
1.0700g/cm3
Appearence

Oxymetazoline is typically found as a white or almost white crystalline powder. It is odorless and has a bitter taste. The compound is soluble in water, alcohol, and propylene glycol, making it amenable to various pharmacological formulations.

Comment on solubility

Solubility of 2-[(2-methylbenzothiophen-3-yl)methyl]-4,5-dihydro-1H-imidazole

The solubility of 2-[(2-methylbenzothiophen-3-yl)methyl]-4,5-dihydro-1H-imidazole can be influenced by several factors, which makes it an interesting compound in terms of solubility behaviors. Here are some essential points to consider:

  • Polarity: The molecular structure suggests some degree of polarity due to the presence of the imidazole ring, which may enhance its solubility in polar solvents.
  • Hydrophobic interactions: The 2-methylbenzothiophen moiety contributes hydrophobic characteristics, potentially decreasing solubility in water and instead favoring non-polar solvents.
  • Solvent effects: Solubility may be maximized in organic solvents such as ethanol or DMSO, while it might exhibit limited solubility in aqueous solutions.
  • Temperature-effects: As with many organic compounds, increasing temperature may enhance solubility by breaking intermolecular forces.

In summary, the solubility of this compound is a complex interplay of structural features and solvent properties. Understanding these interactions can provide insight into suitable applications and methods for formulation in various fields.

Interesting facts

Interesting Facts about 2-[(2-methylbenzothiophen-3-yl)methyl]-4,5-dihydro-1H-imidazole

This intriguing compound, with its complex structure, embodies a unique combination of multiple chemical functionalities. The presence of the benzothiophene and imidazole moieties offers a fascinating insight into its potential applications in various fields:

  • Biological Significance: Compounds structurally similar to this one are often explored for their pharmacological properties. The fusion of heterocycles like imidazole can lead to agents with antimicrobial or antitumor activities.
  • Material Science: The intricate structure of this compound suggests possible use in the development of novel materials, particularly in organic electronics or photovoltaic cells.
  • Synthetic Challenges: The synthesis of such complex organic molecules can pose significant challenges that require advanced techniques like cross-coupling reactions or ring-closing reactions.

Furthermore, the functionality of this compound can be further modified through substituent variations, allowing for the exploration of structure-activity relationships (SAR) which is essential in medicinal chemistry. Through synthetic modifications, scientists can optimize its biological activity while revealing new pathways for application.

In the words of a renowned chemist, "Understanding the nuances of compound design opens doors to innovations that can transform industries." Thus, studying compounds like 2-[(2-methylbenzothiophen-3-yl)methyl]-4,5-dihydro-1H-imidazole not only enhances our chemical knowledge but also ignites curiosity in exploring new horizons in science.

Synonyms
METIZOLINE
Metyzoline
17692-22-7
Metizolina
Metizolinum
Z27L8N105U
2-[(2-methyl-1-benzothiophen-3-yl)methyl]-4,5-dihydro-1H-imidazole
DTXSID9074983
2-(2-methylbenzo(b)thien-3-ylmethyl)-2-imidazoline
1H-Imidazole, 4,5-dihydro-2-((2-methylbenzo(b)thien-3-yl)methyl)-
1H-Imidazole, 4,5-dihydro-2-[(2-methylbenzo[b]thien-3-yl)methyl]-
2-((2-methyl-1-benzothiophen-3-yl)methyl)-4,5-dihydro-1H-imidazole
DTXCID8035631
R01AA10
Benazoline oxalate
Metizoline [INN:BAN]
Metizolinum [INN-Latin]
Metizolina [INN-Spanish]
UNII-Z27L8N105U
METIZOLINE [MI]
METIZOLINE [INN]
Lopac-B-4555
METIZOLINE [WHO-DD]
Lopac0_000192
SCHEMBL249827
CHEMBL1370446
CHEBI:136017
BDBM50417137
CCG-204287
DB13614
SDCCGSBI-0050180.P002
NCGC00015152-01
NCGC00015152-02
NCGC00015152-03
NCGC00015152-04
NCGC00162086-01
Q6824158
2-((2-METHYLBENZO(B)THIEN-3-YL)METHYL)-2-IMIDAZOLINE
2-((2-Methylbenzo[b]thiophen-3-yl)methyl)-4,5-dihydro-1H-imidazole