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Naphthalene-2-acetic acid

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Identification
Molecular formula
C12H10O2
CAS number
581-96-4
IUPAC name
2-(2-naphthyl)acetic acid
State
State

At room temperature, naphthalene-2-acetic acid is typically in a solid state as a crystalline powder.

Melting point (Celsius)
135.00
Melting point (Kelvin)
408.15
Boiling point (Celsius)
315.00
Boiling point (Kelvin)
588.15
General information
Molecular weight
186.21g/mol
Molar mass
186.2070g/mol
Density
1.2880g/cm3
Appearence

Naphthalene-2-acetic acid appears as a white to off-white crystalline powder. It has a characteristic odor that is often described as slightly pungent.

Comment on solubility

Solubility of 2-(2-naphthyl)acetic Acid

2-(2-naphthyl)acetic acid, with its intricate structure, presents specific solubility characteristics that are noteworthy. Understanding its solubility aids in predicting its behavior in various chemical environments and applications.

General Solubility Insights

The solubility of 2-(2-naphthyl)acetic acid can be influenced by several factors:

  • Polarity: The compound features a non-polar naphthyl ring, which generally decreases its solubility in polar solvents, while the carboxylic acid group enhances solubility in polar solutions.
  • Solvent Interactions: It shows better solubility in organic solvents like ethyl acetate and chloroform compared to water.
  • pH Dependency: In acidic conditions, the carboxylic acid retains its proton, reducing solubility in water, whereas in basic conditions, it can ionize and enhance solubility in aqueous solutions.

Practical Considerations

When discussing the solubility of 2-(2-naphthyl)acetic acid, it's essential to note:

  • Its solubility can be described as moderate in water—likely around a few grams per liter.
  • As a solid compound, it is often utilized in formulations where solubility must be optimized for efficacy in biological systems.
  • In pharmaceutical preparations, solubility directly influences absorption and bioavailability, making it a critical factor for research and development.

In summary, the solubility behavior of 2-(2-naphthyl)acetic acid reflects the balance between its polar functional group and non-polar aromatic rings, influencing its applicability in various fields.

Interesting facts

Interesting Facts about 2-(2-naphthyl)acetic Acid

2-(2-naphthyl)acetic acid, often referred to as a naphthalene derivative, is a fascinating compound that has attracted the interest of both chemists and biologists for its unique properties and applications.

Key Features:

  • Biological Importance: This compound has shown potential as a plant growth regulator. It can influence processes such as cell elongation and division, making it vital in agricultural chemistry.
  • Receptor Activity: Research indicates that it may interact with various biochemical receptors, triggering physiological responses that can be beneficial in medicinal chemistry.
  • Synthetic Utility: The structure of 2-(2-naphthyl)acetic acid makes it an excellent building block in organic synthesis, utilized in the production of various pharmaceuticals and fine chemicals.

Furthermore, the unique combination of its aromatic naphthalene system with the carboxylic acid functional group gives this compound remarkable stability and reactivity, making it a valuable substance in both synthetic and natural product chemistry. Scientists have noted that:

"The intricate interplay between structure and function in this compound opens up exciting pathways for innovations in material science and biochemistry."

In summary, 2-(2-naphthyl)acetic acid's role in agricultural and medicinal applications highlights its significance in chemistry and biology, while its synthetic capabilities ensure its place in the toolkit of chemists around the world.

Synonyms
2-Naphthylacetic acid
581-96-4
2-NAPHTHALENEACETIC ACID
Betoxan
2-(2-Naphthyl)acetic acid
beta-Naphthylacetic acid
beta-Naphthaleneacetic acid
Naphthalen-2-ylacetic acid
2-naphthalen-2-ylacetic acid
beta-Naphthaleneacetate
.beta.-Naphthaleneacetic acid
.beta.-Naphthylacetic acid
NSC 301
.beta.-Naphthaleneacetate
Acide beta-naphthylacetique
Acide beta-naphthylacetique [French]
EINECS 209-475-0
CHEBI:37837
NSC-301
202H99Z0CE
NAPHTHYLACETIC ACID, 2-
DTXSID20206825
DTXCID50129316
209-475-0
2-(Naphthalen-2-Yl)Acetic Acid
MFCD00004126
2-naphthyl acetic acid
2-Napthylacetic acid
CHEMBL948
2-naphthalen-2-ylethanoic acid
naphthalene-2-acetic acid
Naphthalen-2-yl-acetic acid
UNII-202H99Z0CE
2-naphtylacetic acid
naphth-2-ylacetic acid
2-NAA
Oprea1_126163
Oprea1_331755
Acide .beta.-naphthylacetique
SCHEMBL238445
NSC301
2-NATHTHALENEACETIC ACID
2-Naphthaleneacetic acid, 99%
acetic acid, 2-(2-naphthyl)-
BDBM16431
ALBB-006271
STK503796
2-Naphthaleneacetic acid (8CI,9CI)
AKOS000121324
AC-5789
CS-W016903
FN33501
FS-3507
GS-0023
HY-W016187
SY005583
DB-021407
N0352
NS00033881
EN300-16682
2-Naphthaleneacetic acid, purum, >=98.0% (T)
Q27104428
Z56754861
F3099-7240
I7L