Skip to main content

Naphthalene-2-butyric acid

ADVERTISEMENT
Identification
Molecular formula
C14H12O2
CAS number
303-49-1
IUPAC name
2-(2-naphthyl)butanoic acid
State
State

At room temperature, Naphthalene-2-butyric acid is in a solid state. It tends to maintain its consistency as a stable solid under standard environmental conditions.

Melting point (Celsius)
125.00
Melting point (Kelvin)
398.15
Boiling point (Celsius)
406.00
Boiling point (Kelvin)
679.15
General information
Molecular weight
212.25g/mol
Molar mass
212.2600g/mol
Density
1.1880g/cm3
Appearence

Naphthalene-2-butyric acid appears as a white to off-white solid crystalline substance. Its crystals are often flaky in nature, and it is commonly found in a powdered form for various applications.

Comment on solubility

Solubility of 2-(2-naphthyl)butanoic acid

2-(2-naphthyl)butanoic acid, also known as naproxen, exhibits notable characteristics regarding its solubility in various solvents. Understanding its solubility profile is essential for its applications in pharmaceutical formulations and other chemical uses.

Solubility Characteristics:

  • Solvent Type: This compound displays better solubility in organic solvents compared to water.
  • Temperature Dependence: Solubility may increase with temperature, which is a common trait for many organic acids.
  • pH Influence: The solubility of 2-(2-naphthyl)butanoic acid can significantly change depending on the pH of the solution, particularly in aqueous environments.
  • Typical Solvents: It is soluble in organic solvents such as ethanol and acetone, making these solvents preferable for dissolving this compound for laboratory or industrial use.

Given these factors, it’s essential to take into account the intended application and the specific conditions when considering the solubility of 2-(2-naphthyl)butanoic acid. Optimizing solubility conditions can enhance the efficacy of the compound in various formulations.

Interesting facts

Interesting Facts about 2-(2-Naphthyl)butanoic Acid

2-(2-Naphthyl)butanoic acid, often referred to in scientific circles as (S)-2-(2-naphthyl)butanoic acid, unveils a myriad of captivating characteristics that make it a subject of interest for both chemists and researchers alike. Here are some notable aspects:

  • Pharmaceutical Applications: This compound has been studied for its potential anti-inflammatory and analgesic properties, contributing to the field of medicinal chemistry.
  • Synthesis: The compound can be synthesized through various organic reactions, showcasing the versatility of synthetic chemistry in creating complex structures with specific functionalities.
  • Chirality: It features chirality, meaning it exists in different enantiomeric forms. This is significant in pharmacology, as the two enantiomers often exhibit different biological activities.
  • Analytical Techniques: Characterization of 2-(2-naphthyl)butanoic acid can be achieved through techniques such as NMR spectroscopy and mass spectrometry, illustrating the importance of analytical chemistry in understanding molecular structure.
  • Research Potential: Ongoing studies explore its efficacy in various therapeutic areas, highlighting the compound's potential as a lead compound in drug development.

As scientists continue to investigate the properties and applications of 2-(2-naphthyl)butanoic acid, it stands as a reminder of the intricate connections between molecular structure, biological activity, and practical applications in the pharmaceutical industry.


Synonyms
2-(naphthalen-2-yl)butanoic acid
15410-83-0
alpha-Ethyl-2-naphthaleneacetic acid
BRN 1961056
2-NAPHTHALENEACETIC ACID, alpha-ETHYL-
SCHEMBL2318137
2-(naphthalen-2-yl)butanoicacid
DTXSID90934926
AKOS011681672
CS-0295753
EN300-1138713