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Naproxen Hydrochloride

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Identification
Molecular formula
C13H15NO·HCl
CAS number
26159-34-2
IUPAC name
2-(2-naphthyl)propylammonium;chloride
State
State

At room temperature, Naproxen Hydrochloride is in a solid state. It is usually found in tablet form when used as a medication, where it is formulated together with other excipients for oral administration.

Melting point (Celsius)
150.10
Melting point (Kelvin)
423.25
Boiling point (Celsius)
233.30
Boiling point (Kelvin)
506.45
General information
Molecular weight
235.67g/mol
Molar mass
235.6690g/mol
Density
1.0750g/cm3
Appearence

Naproxen Hydrochloride is typically a white to off-white crystalline powder. It is generally odorless and has a bitter taste, which is common for many pharmaceutical compounds.

Comment on solubility

Solubility of 2-(2-naphthyl)propylammonium chloride

The solubility of 2-(2-naphthyl)propylammonium chloride can be characterized by several important aspects that reflect its interaction with solvents:

  • Solubilization in Water: This compound is generally considered to have moderate solubility in water. The presence of the quaternary ammonium group enhances ionic interactions in aqueous solutions.
  • Cationic Nature: As a cationic compound, 2-(2-naphthyl)propylammonium reacts favorably with polar solvents. This characteristic often leads to its inclusion in formulations such as surfactants, where its solubility can be beneficial.
  • Organic Solvent Compatibility: The naphthyl group presents a bulkier hydrocarbon structure, which may hinder solubility in nonpolar organic solvents. Yet, it can still dissolve in some polar organic solvents due to the ammonium group's ability to interact with them.

In summary, the solubility profile of 2-(2-naphthyl)propylammonium chloride emphasizes:

  • Moderate aqueous solubility due to ionic characteristics.
  • Enhanced ion-dipole interactions with polar solvents.
  • Potential limitations when interacting with nonpolar media.

Understanding these solubility properties is essential for applications in various fields such as pharmaceuticals, where solubility can significantly impact bioavailability and efficacy.

Interesting facts

Interesting Facts about 2-(2-naphthyl)propylammonium Chloride

2-(2-naphthyl)propylammonium chloride, often referred to in the scientific community as a fascinating organic compound, holds significance in various fields of chemistry. Here are some noteworthy points:

  • Ammonium Ion: This compound features an ammonium ion, which is known for its role in biological systems. It is a crucial component in the structure of amino acids and proteins.
  • Naphthalene Structure: The inclusion of the naphthyl group adds aromatic features to the compound. Naphthalene is well-known for its unique properties and is often associated with applications in organic synthesis and materials science.
  • Ion Pair Chemistry: As a quaternary ammonium salt, 2-(2-naphthyl)propylammonium chloride is of considerable interest in ion pair chemistry, which is relevant for studies in electrolyte solutions and surfactant behavior.
  • Potential Applications: Compounds of this nature may have applications in the pharmaceutical industry, particularly as drug delivery agents or in the design of new therapeutic compounds.
  • Research Relevance: The study of similar compounds can lead to insights into various chemical phenomena, such as solubility, ionic strength, and molecular interactions.

In the realm of organic chemistry, compounds like 2-(2-naphthyl)propylammonium chloride exemplify the intricate interplay between structure and reactivity. As quoted by renowned chemist Linus Pauling, "The secret of a good chemistry is the control of the quantity of all the various ingredients." This highlights the importance of understanding the unique characteristics and behaviors of such unique compounds.

Synonyms
dl-alpha-Methyl-2-naphthaleneethylamine hydrochloride
2-naphthalen-2-ylpropylazanium;chloride
dl-alpha-Metil-2-naftoetilamina HCl [Italian]
dl-alpha-Metil-2-naftoetilamina HCl
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