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2-(2-nitroanilino)acetic acid

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Identification
Molecular formula
C8H8N2O4
CAS number
13073-76-0
IUPAC name
2-(2-nitroanilino)acetic acid
State
State

This compound is typically a solid at room temperature. It is an aromatic compound with a relatively high melting point, characteristic of many organic solids containing nitro groups.

Melting point (Celsius)
200.00
Melting point (Kelvin)
473.15
Boiling point (Celsius)
300.00
Boiling point (Kelvin)
573.15
General information
Molecular weight
196.16g/mol
Molar mass
196.1640g/mol
Density
1.6130g/cm3
Appearence

2-(2-Nitroanilino)acetic acid is typically a yellow solid. This color is due to the presence of the nitro group, which is a characteristic chromophore that often imparts yellow to orange colors in aromatic compounds.

Comment on solubility

Solubility of 2-(2-nitroanilino)acetic acid

2-(2-nitroanilino)acetic acid exhibits specific solubility characteristics that are influenced by its structural features. This compound is generally soluble in organic solvents due to its aromatic ring structure and presence of functional groups that can participate in interactions with solvent molecules.

Factors Affecting Solubility:

  • Polarity: The presence of the carboxylic acid group (–COOH) imparts some polarity to the compound, enhancing its solubility in polar solvents such as water, albeit to a limited extent.
  • Hydrogen Bonding: The ability to form hydrogen bonds due to the carboxyl group can facilitate interactions with solvents capable of hydrogen bonding.
  • Substituent Effects: The nitro group on the aniline moiety can affect the electronic properties of the compound, potentially influencing solubility as well.

In summary, while 2-(2-nitroanilino)acetic acid may display moderate solubility in water, its solubility is enhanced in less polar organic solvents. Therefore, it is often advisable to consider the solvent choice based on the intended application or experimental conditions. Understanding these solubility parameters is crucial for its effective use in various chemical processes.

Interesting facts

Interesting Facts about 2-(2-nitroanilino)acetic acid

2-(2-nitroanilino)acetic acid is a fascinating chemical compound that belongs to the class of amino acids. This compound features a unique structure with multiple functional groups that enhance its reactivity and applications in various fields. Here are some interesting facts:

  • Functional Diversity: The presence of both an amine group and a nitro group makes this compound a subject of interest for medicinal chemistry and organic synthesis.
  • Biological Relevance: Compounds like 2-(2-nitroanilino)acetic acid have been studied for their potential biological activities, particularly in developing pharmaceutical agents.
  • Colorimetry Applications: Due to the nitro group, this compound can participate in colorimetric reactions, enabling its use as a reagent in various analytical techniques.

This compound exemplifies the importance of structural intricacies in determining the properties and applications of organic molecules. In the words of a famous chemist, "The beauty of chemistry lies in the detail." The exploration of compounds like 2-(2-nitroanilino)acetic acid reveals the interconnectedness of structure, function, and reactivity in the vast world of chemistry.

Researchers continue to investigate such molecules not only for their intrinsic properties but also for their role in advancing technology and medicine. The ongoing studies highlight the significance of these compounds in developing new therapies and diagnostics, further underscoring the importance of chemistry in enhancing human welfare.

Synonyms
2-[(2-nitrophenyl)amino]acetic acid
5427-99-6
N-o-nitrophenylglycine
2-((2-nitrophenyl)amino)acetic acid
2-(2-nitroanilino)acetic acid
GLYCINE, N-(o-NITROPHENYL)-
[(2-Nitrophenyl)amino]acetic acid
N-(o-Nitrophenyl)glycine
NSC 12787
BRN 2808405
NSC12787
(2-nitrophenyl)glycine
Oprea1_546283
SCHEMBL124292
DTXSID70202630
FAA42799
2-[(2-nitrophenyl)amino]aceticacid
MFCD00771928
NSC-12787
AKOS000181311
CS-0251056
EN300-53388
G37648
Z57226712
F1905-0002