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Benzoxazinoic acetamide

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Identification
Molecular formula
C10H8N2O3
CAS number
82-16-6
IUPAC name
2-(2-oxo-4H-1,3-benzoxazin-3-yl)acetamide
State
State

At room temperature, this compound is usually found in a solid state.

Melting point (Celsius)
231.00
Melting point (Kelvin)
504.00
Boiling point (Celsius)
340.00
Boiling point (Kelvin)
613.00
General information
Molecular weight
194.18g/mol
Molar mass
194.1840g/mol
Density
1.3500g/cm3
Appearence

The compound typically appears as a white crystalline solid and may have a slightly powdery texture. It is generally colorless to pale yellow, depending on purity.

Comment on solubility

Solubility of 2-(2-oxo-4H-1,3-benzoxazin-3-yl)acetamide

The solubility of 2-(2-oxo-4H-1,3-benzoxazin-3-yl)acetamide can be characterized by several critical factors:

  • Polarity: Compounds with polar functional groups tend to be more soluble in polar solvents, such as water. This compound contains both amide and carbonyl groups which can engage in hydrogen bonding, potentially enhancing its solubility.
  • Structural Considerations: The presence of the benzoxazin moiety may affect solubility due to its aromatic structure, often leading to lower solubility in aqueous solutions compared to aliphatic compounds.
  • Temperature Influence: Solubility can significantly increase with temperature. Therefore, experimenting at higher temperatures might yield increased dissolution rates for this compound.
  • Solvent Choice: The choice of solvent is crucial. While it may be moderately soluble in polar solvents, its solubility in organic solvents such as ethanol or dimethyl sulfoxide (DMSO) is also worth investigating due to potential compatibility.
  • pH Dependency: As an amide, the solubility of this compound may vary with changes in acidic or basic conditions, impacting the ionization state and overall solubility.

In summary, while the specific solubility data for 2-(2-oxo-4H-1,3-benzoxazin-3-yl)acetamide is not extensively documented, factors including polarity, structure, and environment play significant roles in determining its solubility profile. Conducting empirical tests is essential for accurate solubility assessments.

Interesting facts

Exploring 2-(2-oxo-4H-1,3-benzoxazin-3-yl)acetamide

2-(2-oxo-4H-1,3-benzoxazin-3-yl)acetamide is a fascinating compound that belongs to the class of benzoxazines, which are notable for their heterogeneous nature and versatility in various applications. Here are some interesting facts to consider:

  • Unique Structure: The compound features a benzoxazine structure, which incorporates a fused benzene and oxazine ring. This unique architecture contributes to its chemical properties and potential reactivity.
  • Biological Activity: Compounds in the benzoxazine family have been found to exhibit a range of biological activities. Research has indicated that derivatives may possess anti-cancer, anti-inflammatory, or antimicrobial properties, making them an intriguing area of study.
  • Material Science Applications: Due to their thermal stability, some benzoxazine-containing compounds are utilized in advanced materials, including epoxy resins and coatings. This could indicate potential applications of 2-(2-oxo-4H-1,3-benzoxazin-3-yl)acetamide in enhanced material performance.
  • Synthetic Versatility: The synthesis of benzoxazine derivatives often involves straightforward methodologies, making them accessible for laboratory synthesis. This ease of synthesis allows for the exploration of numerous analogs to study their properties and applications.
  • Potential Research Avenues: The compound may serve as a lead structure for further synthetic explorations. Scientists can investigate modifications and substitutions on the compound to tailor its properties for specific applications in pharmaceuticals or materials science.

As research continues to evolve, the study of 2-(2-oxo-4H-1,3-benzoxazin-3-yl)acetamide promises to uncover new insights into its mechanisms and broader applications. It embodies the intersection of organic chemistry and material science while offering opportunities for multidisciplinary research.

Synonyms
Caroxazone
18464-39-6
Caroxazona
Carossazone
Caroxazonum
F.I. 6654
2-Oxo-2H-1,3-benzoxazine-3(4H)-acetamide
FI-6654
2H-1,3-Benzoxazine-3(4H)-acetamide, 2-oxo-
807N226MNL
DTXSID10171598
2-(2-oxo-3,4-dihydro-2H-1,3-benzoxazin-3-yl)acetamide
4H-3-methylcarboxamide-1,3-benzoxazin-2-one
2,3-dihydro-4H-1,3-benzoxazin-2-one-3-acetamide
DTXCID4094089
242-345-1
2-(2-oxo-4H-1,3-benzoxazin-3-yl)acetamide
Timostenil
Carossazone [DCIT]
Caroxazone [USAN:INN]
Caroxazonum [INN-Latin]
Caroxazona [INN-Spanish]
FI 6654
EINECS 242-345-1
3-Acetamide-4H-1,3-benzoxazin-2-one
BRN 1216828
UNII-807N226MNL
4H-3-Methylcarboxamide-3-benzoxazin-2-one
4H-3-Carbamoylmethyl-1,3-benzoxazin-2-one
CAROXAZONE [MI]
CAROXAZONE [INN]
Caroxazone (USAN/INN)
CAROXAZONE [USAN]
CAROXAZONE [MART.]
4H-1,3-BENZOXAZIN-2-ONE, 3-ACETAMIDE
SCHEMBL49746
orb1702454
CHEMBL2104164
SCHEMBL30020763
CHEBI:134867
KYCBWEZLKCTALM-UHFFFAOYSA-N
GLXC-02868
AKOS040746668
DB09254
NCGC00522199-02
HY-119774
CS-0077970
NS00026060
D03409
EN300-255083
Q5045573
BRD-K92129045-001-01-6
Z1509385480