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Piracetam

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Identification
Molecular formula
C6H10N2O2
CAS number
7491-74-9
IUPAC name
2-(2-oxopyrrolidin-1-yl)acetamide
State
State

At room temperature, piracetam is a solid.

Melting point (Celsius)
151.00
Melting point (Kelvin)
424.15
Boiling point (Celsius)
208.00
Boiling point (Kelvin)
481.15
General information
Molecular weight
142.16g/mol
Molar mass
142.1570g/mol
Density
1.2300g/cm3
Appearence

Piracetam is typically found as a white or almost white powder. It is crystalline in nature and can appear as small, crystalline aggregates.

Comment on solubility

Solubility of 2-(2-oxopyrrolidin-1-yl)acetamide

The solubility of 2-(2-oxopyrrolidin-1-yl)acetamide, with the chemical formula C6H10N2O2, in various solvents is of significant interest in both academic research and practical applications. This compound is generally characterized by its:

  • Moderate solubility in polar solvents: Compounds that contain both nitrogen and oxygen often exhibit enhanced solubility in water and alcohols due to hydrogen bonding.
  • Limited solubility in non-polar solvents: The presence of polar functional groups tends to hinder solubility in organic solvents like hexane or toluene.

Factors influencing this solubility include:

  1. Hydrogen bonding: The ability of the amide functional group to form hydrogen bonds with solvent molecules plays a crucial role in solubility.
  2. Molecular structure: The size and shape of the 2-(2-oxopyrrolidin-1-yl)acetamide molecule contributes to how it interacts with solvents.
  3. Temperature: As with many compounds, increasing the temperature can enhance solubility, making it a vital consideration during experiments.

Understanding these solubility characteristics is essential when considering the formulation of drug preparations and the development of chemical processes involving 2-(2-oxopyrrolidin-1-yl)acetamide. As a rule of thumb, always consult solubility charts and conduct empirical tests to ascertain the compound's behavior in specific solvent systems.

Interesting facts

Exploring 2-(2-Oxopyrrolidin-1-yl)acetamide

2-(2-oxopyrrolidin-1-yl)acetamide, often referred to in scientific circles for its structural and functional properties, is a compound that may pique the interest of both chemists and pharmacologists. Here are some intriguing facts about the compound:

  • Structural Significance: The compound features a unique oxopyrrolidine ring, which is vital for its biological activity.
  • Pharmaceutical Potential: This compound has been studied in various contexts within medicinal chemistry, particularly as it interacts with biological systems.
  • Amide Bond: The presence of the amide functional group in its structure can enhance polarity and solubility, making it a candidate for drug formulation.
  • Applications: Research indicates that derivatives of this compound could potentially act in roles such as anti-inflammatory or neuroprotective agents.
  • Versatile Intermediates: The compound can serve as an intermediate in the synthesis of more complex molecules, showcasing the importance of such amides in organic synthesis.

As stated by leading chemists, "Understanding the nuances of small molecules can unlock the door to major therapeutic advancements." This emphasizes the value of 2-(2-oxopyrrolidin-1-yl)acetamide and its derivatives in contributing to the field of drug development. Continued research may reveal even more applications and insights into its potential.

Synonyms
piracetam
7491-74-9
2-(2-oxopyrrolidin-1-yl)acetamide
Nootropil
2-Oxo-1-pyrrolidineacetamide
1-Pyrrolidineacetamide, 2-oxo-
Nootropyl
Pyracetam
Normabrain
Gabacet
Pyramem
Ciclofalina
Euvifor
Genogris
Nootron
Pirazetam
Pirroxil
2-Pyrrolidinoneacetamide
Myocalm
2-Pyrrolidoneacetamide
2-Oxo-pyrrolidine acetamide
Piracetamum
Breinox
Naofukang
Cl-871
1-Acetamido-2-pyrrolidinone
2-(2-oxo-pyrrolidin-1-yl)acetamide
2-Oxo-pyrrolidin-1-ylacetamide
2-Ketopyrrolidine-1-ylacetamide
UCB 6215
KT-801
UCB-6215
EINECS 231-312-7
UNII-ZH516LNZ10
NSC-758191
BRN 1526393
ZH516LNZ10
MLS000069719
HSDB 7529
MFCD00079246
SMR000058196
2-(2-Oxopyrrolidino)acetamide
DTXSID5044491
5-21-06-00360 (Beilstein Handbook Reference)
NSC 758191
NCGC00015821-02
CAS-7491-74-9
PIRACETAM (MART.)
PIRACETAM [MART.]
Naofukang [Chinese]
DTXCID3024491
PIRACETAM (EP MONOGRAPH)
PIRACETAM [EP MONOGRAPH]
Cerebroforte
Avigilen
Nootrop
Norzetam
Axonyl
Geram
Piracetamum [INN-Latin]
2-Pyrrolidone-N-Acetamide
SR-01000076071
Encetrop
Piracetam [USAN:INN:BAN]
Piracetam,(S)
Prestwick_870
Myocalm (TN)
Piracetam (Standard)
Piracetam, EP6.0
Spectrum_001421
PIRACETAM [INN]
PIRACETAM [JAN]
PIRACETAM [MI]
PIRACETAM [HSDB]
PIRACETAM [USAN]
Opera_ID_1766
Prestwick0_000537
Prestwick1_000537
Prestwick2_000537
Prestwick3_000537
Spectrum2_001074
Spectrum3_001523
Spectrum4_000742
Spectrum5_001037
Lopac-P-5295
cid_4843
PIRACETAM [WHO-DD]
Lopac0_000949
Oprea1_512927
SCHEMBL20172
BSPBio_000553
BSPBio_002906
KBioGR_001064
KBioSS_001901
Piracetam (JAN/USAN/INN)
2-Oxo-1-pyrrolidinylacetamide
CHEMBL36715
DivK1c_000259
SPECTRUM1502195
Piracetam - Bio-X trade mark
SPBio_001088
SPBio_002474
2-(2-ketopyrrolidino)acetamide
BPBio1_000609
GTPL4288
BDBM62877
CHEBI:32010
Cl-781
HMS500M21
HY-B0585R
KBio1_000259
KBio2_001901
KBio2_004469
KBio2_007037
KBio3_002406
N06BX03
NINDS_000259
HMS1569L15
HMS1921L12
HMS2092D18
HMS2096L15
HMS2230B24
HMS3262N20
HMS3371G01
HMS3657A05
HMS3713L15
HMS3885I07
Pharmakon1600-01502195
BCP28414
EDC79964
HY-B0585
2-(2-Oxo-1-pyrrolidinyl)acetamide
Tox21_110229
Tox21_301990
Tox21_500949
BBL028161
CCG-39282
HB0507
NSC758191
s3070
STK535612
AKOS001038683
Tox21_110229_1
2-(2-Oxo-1-pyrrolidinyl)acetamide #
DB09210
LP00949
SDCCGSBI-0050923.P004
IDI1_000259
NCGC00015821-01
NCGC00015821-03
NCGC00015821-04
NCGC00015821-05
NCGC00015821-06
NCGC00015821-07
NCGC00015821-08
NCGC00015821-10
NCGC00015821-21
NCGC00094253-01
NCGC00094253-02
NCGC00094253-03
NCGC00094253-04
NCGC00255727-01
NCGC00261634-01
AC-33158
AS-13920
BP166248
SY066794
SBI-0050923.P003
DB-019407
AB00052287
EU-0100949
NS00000504
P2880
SW196995-3
2-(2-oxidanylidenepyrrolidin-1-yl)ethanamide
EN300-17044
Piracetam, VETRANAL(TM), analytical standard
D01914
P 5295
AB00052287_12
AE-641/30117005
Q410069
SR-01000076071-1
SR-01000076071-4
SR-01000076071-6
BRD-K19456237-001-22-7
BRD-K19456237-001-26-8
BRD-K19456237-001-27-6
Z56865289
Piracetam, European Pharmacopoeia (EP) Reference Standard
2-Oxo-1-pyrrolidineacetamide;(2-Oxopyrrolidino)acetamide;2-(2-Oxopyrrolidin-1-yl)acetamide
231-312-7