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2-(2-Phenoxyethyl)guanidine

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Identification
Molecular formula
C9H13N3O
CAS number
33228-21-0
IUPAC name
2-(2-phenoxyethyl)guanidine
State
State

At room temperature, 2-(2-Phenoxyethyl)guanidine is typically in a solid state, either as a crystalline solid or an amorphous powder.

Melting point (Celsius)
118.00
Melting point (Kelvin)
391.15
Boiling point (Celsius)
274.00
Boiling point (Kelvin)
547.15
General information
Molecular weight
193.25g/mol
Molar mass
193.2470g/mol
Density
1.0990g/cm3
Appearence

2-(2-Phenoxyethyl)guanidine typically appears as a crystalline solid or powder. It is white to off-white in color and may exhibit a slight odor typical of organic compounds containing guanidino groups.

Comment on solubility

Solubility of 2-(2-phenoxyethyl)guanidine

The solubility of 2-(2-phenoxyethyl)guanidine in various solvents is an intriguing aspect of its chemical properties. This compound is generally considered to have moderate solubility characteristics. To better understand its solubility, let’s explore the influential factors:

  • Polar vs. Non-Polar Solvents: Due to its guanidine functional group, which can engage in hydrogen bonding, 2-(2-phenoxyethyl)guanidine tends to be more soluble in polar solvents like water and alcohols compared to non-polar solvents.
  • Temperature Dependence: Like many organic compounds, the solubility of 2-(2-phenoxyethyl)guanidine may increase with temperature. Higher temperatures generally enhance solubility by allowing greater molecular motion.
  • Molecular Interactions: The presence of the phenoxyethyl group can also affect solubility. This group can lead to substitution interactions, which may either enhance or reduce solubility depending on the solvent polarity.

In conclusion, while 2-(2-phenoxyethyl)guanidine demonstrates moderate solubility in polar solvents, it is crucial to consider the specific solvent environment and temperature conditions to predict its behavior accurately. As with many compounds, understanding the nuances of solubility can lead to better applications in research and industry!

Interesting facts

Interesting Facts about 2-(2-phenoxyethyl)guanidine

2-(2-phenoxyethyl)guanidine is an intriguing compound that has garnered attention in various fields of research due to its unique structure and potential applications. Here are some fascinating points to consider:

  • Pharmacological Potential: This compound is noted for its biological activity, particularly its role in modulating the nervous system. Its interactions with specific receptors have led to investigations into its potential as a therapeutic agent for various neurological disorders.
  • Sympathomimetic Effects: Researchers have studied the sympathomimetic effects of 2-(2-phenoxyethyl)guanidine. The compound can mimic the actions of the sympathetic nervous system, which could have implications in treating conditions related to low blood pressure or certain forms of shock.
  • Structure-Activity Relationship: The compound's unique chemical structure allows scientists to explore the structure-activity relationship (SAR) to understand how variations in its structure might enhance or diminish its biological effects. This is a crucial aspect of drug development.
  • Synthesis Techniques: The synthesis of 2-(2-phenoxyethyl)guanidine often involves straightforward chemical reactions, making it relatively accessible for laboratory studies. This enhances its utility in academic and pharmaceutical research settings.
  • Studying Mechanisms: Scientists are keen to study the mechanisms by which 2-(2-phenoxyethyl)guanidine operates at the molecular level, which could unveil new pathways for drug discovery and lead to innovations in treatments related to the nervous system.

In summary, 2-(2-phenoxyethyl)guanidine stands as a significant compound within the realm of medicinal chemistry, offering a rich area for exploration and potential breakthroughs in therapeutic strategies. With its multifaceted properties and pharmacological potential, this compound continues to engage the curiosity of scientists and researchers worldwide.

Synonyms
(2-Phenoxyethyl)guanidine
GUANIDINE, (2-PHENOXYETHYL)-
BRN 2526529
46231-41-8
DTXSID20196777
DTXCID60119268
SCHEMBL10310294
SCHEMBL17046781
AKOS009145692