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Phenylpropanolamine hydrochloride

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Identification
Molecular formula
C9H15NO2+ Cl-
CAS number
154-41-6
IUPAC name
2-(2-phenyl-1,3-dioxolan-4-yl)piperidin-1-ium;chloride
State
State

At room temperature, phenylpropanolamine hydrochloride is in a solid state, appearing commonly as a crystalline powder.

Melting point (Celsius)
168.00
Melting point (Kelvin)
441.15
Boiling point (Celsius)
285.00
Boiling point (Kelvin)
558.15
General information
Molecular weight
219.72g/mol
Molar mass
219.7170g/mol
Density
1.1800g/cm3
Appearence

Phenylpropanolamine hydrochloride typically appears as a white or almost white crystalline powder. It is odorless or may have a faint odor. The compound is usually highly soluble in water and exhibits a negligible solubility in alcohol, acetone, and ether.

Comment on solubility

Solubility of 2-(2-phenyl-1,3-dioxolan-4-yl)piperidin-1-ium;chloride

The compound 2-(2-phenyl-1,3-dioxolan-4-yl)piperidin-1-ium;chloride exhibits specific solubility properties that are essential to understand for its application in various chemical processes. Here are some key points regarding its solubility:

  • Solubility in Water: This compound is likely to be soluble in water due to the presence of the +1 charged piperidinium moiety that can interact favorably with polar solvent molecules.
  • Solubility in Organic Solvents: Given its organic structure with phenyl and dioxolane groups, it may have moderate solubility in organic solvents. Common solvents that could dissolve this compound include:
    • Ethyl acetate
    • Dichloromethane
    • Acetone
  • Temperature Dependence: The solubility may increase with temperature, making it essential to consider temperature variations in experimental setups.
  • Effect of pH: The solubility might also be influenced by the pH of the solution, as the ionization state of the piperidinium group can vary with the pH, potentially impacting its solubility characteristics.

In conclusion, understanding the solubility of this compound is crucial for optimizing its use in laboratory and industrial applications. The intricate balance between polar and non-polar characteristics greatly influences its interaction with solvents, making solubility an essential factor in its practical usage.

Interesting facts

Interesting Facts about 2-(2-phenyl-1,3-dioxolan-4-yl)piperidin-1-ium;chloride

2-(2-phenyl-1,3-dioxolan-4-yl)piperidin-1-ium;chloride is a fascinating compound that lies at the intersection of organic chemistry and medicinal applications. Here are some intriguing aspects of this compound:

  • Dual Functional Groups: The compound features both a piperidine ring and a dioxolane moiety. This diverse structure opens avenues for unique reactivity and potential biological activity.
  • Medicinal Chemistry Potential: With its complex structure, researchers are exploring its potential effects in drug design. Compounds with such structural characteristics often exhibit interesting pharmacological properties.
  • Coordination Chemistry: The presence of an ionic component (the chloride ion) suggests possible interactions with other chemical species, making it suitable for studies in coordination chemistry.

One interesting aspect of this compound is the ability of the dioxolane segment to stabilize positive charges, which could enhance the compound's reactivity with various biological targets.

Furthermore, because of its intricate design, this compound embodies the notion that “structure determines function.” It serves as a reminder that small changes in molecular structure can lead to significant variations in biological activity.

Overall, 2-(2-phenyl-1,3-dioxolan-4-yl)piperidin-1-ium;chloride represents a promising area of study, offering a bold step toward innovative drug development!

Synonyms
2-Phenyl-4-(2-piperidyl)-1,3-dioxolane hydrochloride
7456-94-2
1,3-DIOXOLANE, 2-PHENYL-4-(2-PIPERIDYL)-, HYDROCHLORIDE