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Phenibut

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Identification
Molecular formula
C10H13NO2
CAS number
1078-21-3
IUPAC name
2-(2-phenylethylamino)butanedioic acid
State
State

At room temperature, phenibut exists as a solid. It retains this form under standard conditions, making it easy to handle and measure for various applications.

Melting point (Celsius)
194.00
Melting point (Kelvin)
467.15
Boiling point (Celsius)
286.00
Boiling point (Kelvin)
559.15
General information
Molecular weight
179.22g/mol
Molar mass
179.2180g/mol
Density
1.1290g/cm3
Appearence

Phenibut typically appears as a white crystalline powder. It is often characterized by its fine texture and purity, lacking any significant coloration or impurities.

Comment on solubility

Solubility of 2-(2-phenylethylamino)butanedioic acid

The solubility of 2-(2-phenylethylamino)butanedioic acid in various solvents is an intriguing aspect of its chemical behavior. This compound, being an amino acid derivative, exhibits both hydrophilic and hydrophobic properties, making its solubility dependent on several factors.

  • Water Solubility: The presence of the carboxylic acid groups provides some degree of solubility in water. However, the bulky phenyl ethyl moiety may hinder full dissolution.
  • Organic Solvents: The compound is likely to show improved solubility in organic solvents such as ethanol or dimethyl sulfoxide (DMSO), which can better accommodate its hydrophobic characters.
  • pH Dependence: The solubility of the compound can significantly change with pH. At lower pH levels, it may exist predominantly in its protonated form, enhancing solubility due to ionic interactions.

In summary, the solubility of 2-(2-phenylethylamino)butanedioic acid is influenced by a combination of intermolecular interactions, solvent polarity, and environmental conditions. Understanding these factors is essential for applications involving this compound in pharmaceutical and biochemical contexts.

Interesting facts

Exploring 2-(2-phenylethylamino)butanedioic acid

2-(2-phenylethylamino)butanedioic acid is a fascinating compound that showcases the intriguing interplay between organic chemistry and medicinal applications. This compound belongs to the class of amino acids, and its unique structure lends itself to various biological activities.

Key Features of 2-(2-phenylethylamino)butanedioic acid:

  • Amino Functionality: The presence of the amino group contributes to the basic properties of this compound, making it a potential candidate for physiological interactions.
  • Phenethylamine Structure: The phenethylamine portion can enhance the bioactivity, influencing neurotransmitter systems and possibly playing a role in mood regulation.
  • Therapeutic Potential: Compounds with similar structures have been studied for their effects in treating conditions such as depression and anxiety, shedding light on their significance in pharmaceutical chemistry.
  • Custom Synthesis: The synthesis of this compound provides an interesting challenge for chemists, as it often involves intricate organic synthesis techniques.

Additionally, its role as a building block for more complex molecules makes it a subject of interest for researchers involved in drug discovery. As stated by one prominent researcher, "Compounds such as 2-(2-phenylethylamino)butanedioic acid remind us of the beautiful complexity of life at the molecular level." This underscores the importance of studying such compounds not only for their individual properties but also for their contributions to the broader field of medicinal chemistry.

In summary, 2-(2-phenylethylamino)butanedioic acid represents a vibrant area of study, at the intersection of organic synthesis, medicinal chemistry, and biological activity. Its diverse applications and inherent complexity continue to inspire ongoing research in the scientific community.

Synonyms
DL-N-Phenethylaspartic acid
5872-49-1
2-(2-phenylethylamino)butanedioic acid
Acido N-fenetil-DL-aspartico [Italian]
BRN 2943891
Acido N-fenetil-DL-aspartico
ASPARTIC ACID, N-PHENETHYL-, DL-
N-(2-phenylethyl)aspartic acid
SCHEMBL19419061
DTXSID70974244
DB-326243