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Aminoguanidine

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Identification
Molecular formula
C2H7N3
CAS number
79-17-4
IUPAC name
2-(2-phenylethylamino)guanidine
State
State

At room temperature, aminoguanidine is generally found as a crystalline solid. It is stable under normal conditions but should be handled in a moisture-free environment due to its hygroscopic nature.

Melting point (Celsius)
166.50
Melting point (Kelvin)
439.65
Boiling point (Celsius)
298.15
Boiling point (Kelvin)
571.30
General information
Molecular weight
101.12g/mol
Molar mass
101.1240g/mol
Density
1.2868g/cm3
Appearence

Aminoguanidine is typically a white to off-white crystalline powder. It is known for being hygroscopic, which means it can absorb moisture from the air. This compound generally appears uniform in texture without any distinguishable visible features.

Comment on solubility

Solubility of 2-(2-phenylethylamino)guanidine

The solubility of 2-(2-phenylethylamino)guanidine is influenced by several factors, including its structure and functional groups. As a guanidine derivative, it displays unique solubility characteristics:

  • Polarity: The compound consists of both hydrophilic (the guanidine moiety) and hydrophobic (the phenethyl group) sections. This duality impacts its solubility in different solvents.
  • Polar Solvents: 2-(2-phenylethylamino)guanidine is generally more soluble in polar solvents such as water and methanol due to the capability of guanidine to form hydrogen bonds.
  • Non-Polar Solvents: Conversely, its solubility in non-polar solvents is quite limited due to the hydrophobic nature of the phenethyl group. Thus, one may observe decreased solubility in solvents like hexane or toluene.

In summary, the solubility of 2-(2-phenylethylamino)guanidine reflects an interesting balance between its polar and non-polar characteristics. Understanding these solubility properties is essential for predicting its behavior in various chemical environments.

Interesting facts

Interesting Facts about 2-(2-phenylethylamino)guanidine

2-(2-phenylethylamino)guanidine is a fascinating compound with notable applications and characteristics that would pique the interest of both chemists and students alike. Here are some intriguing aspects:

  • Pharmaceutical Potential: This compound has been explored for its potential use in various pharmaceutical applications, particularly as an anti-inflammatory agent. Research is ongoing to fully understand its therapeutic properties.
  • Mode of Action: The unique structure of 2-(2-phenylethylamino)guanidine allows for interesting interactions with biological systems, showcasing a mechanism that can influence physiological processes. Scientists are particularly interested in how it interacts at the molecular level.
  • Structure-Activity Relationship: The study of this compound has contributed to the broader understanding of the structure-activity relationship (SAR) in medicinal chemistry. Modifications to its structure can lead to variations in biological activity, providing valuable insights for drug design.
  • Cross-disciplinary Interest: Its intriguing properties make it a subject of interest not only in organic and medicinal chemistry but also in biochemistry and pharmacology. This cross-disciplinary appeal motivates collaboration among scientists from different fields.
  • Analytical Methods: The analysis of 2-(2-phenylethylamino)guanidine can involve several sophisticated techniques, such as HPLC and NMR spectroscopy, which are essential in confirming purity and elucidating structure.
  • Research Opportunities: As the field of medicinal chemistry advances, new research opportunities continue to emerge surrounding this compound. Its potential role in developing future therapies makes it a valuable subject for study.

In summary, 2-(2-phenylethylamino)guanidine is not merely a compound of chemical interest; it represents the intersection of chemistry and medicine, driving innovation and discovery in ways that continue to evolve as research proceeds. As a student or scientist, exploring this compound could lead to exciting new revelations in the world of pharmacology and beyond.

Synonyms
Phenylethylguanidine
Phenethylaminoguanidine
Guanidine, (2-phenylethyl)-
GUANIDINE, PHENETHYLAMINO-
Guanidine, (2-phenylethyl)-(9CI)
DTXSID30968588
AKOS006277944
2-(2-Phenylethyl)hydrazine-1-carboximidamide