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PB28

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Identification
Molecular formula
C18H22N2O
CAS number
933628-78-9
IUPAC name
2-[2-[phenyl(p-tolyl)methoxy]ethyl]guanidine
State
State

At room temperature, 2-[2-[phenyl(p-tolyl)methoxy]ethyl]guanidine is a solid. This form allows it to be used typically in laboratory settings where solid reagents are required. It maintains its solid state until it reaches its melting point.

Melting point (Celsius)
115.00
Melting point (Kelvin)
388.15
Boiling point (Celsius)
225.00
Boiling point (Kelvin)
498.15
General information
Molecular weight
339.44g/mol
Molar mass
339.4400g/mol
Density
1.1000g/cm3
Appearence

2-[2-[Phenyl(p-tolyl)methoxy]ethyl]guanidine typically appears as a white to off-white crystalline solid. The compound's crystalline nature gives it a characteristic powdery texture and appearance. It is usually odorless and stable under standard conditions of temperature and pressure.

Comment on solubility

Solubility of 2-[2-[phenyl(p-tolyl)methoxy]ethyl]guanidine

The solubility of 2-[2-[phenyl(p-tolyl)methoxy]ethyl]guanidine can be influenced by several factors, mainly its polar and non-polar characteristics. In general, this compound demonstrates:

  • Moderate Solubility in organic solvents, such as ethanol and acetone, due to its aromatic components that provide hydrophobic interactions.
  • Lower Solubility in water, stemming from the presence of bulky phenyl and tolyl groups that hinder hydrogen bonding with water molecules.
  • Temperature Dependency, meaning that solubility may increase with temperature, as higher temperatures typically increase kinetic energy and break intermolecular interactions.

Furthermore, factors such as pH and ionic strength of the solvent can affect the solubility of this compound significantly. For instance, in highly acidic or basic environments, the guanidine functional group can ionize, which potentially enhances solubility. Thus, the solubility of 2-[2-[phenyl(p-tolyl)methoxy]ethyl]guanidine can be summarized as:

  1. Variability depending on the solvent type
  2. Influence from temperature and pH levels
  3. Significant effects of molecular structure on solubility behavior

In conclusion, when working with this compound, it is crucial to consider these solubility aspects for effective application and formulation.

Interesting facts

Interesting Facts about 2-[2-[Phenyl(p-tolyl)methoxy]ethyl]guanidine

2-[2-[Phenyl(p-tolyl)methoxy]ethyl]guanidine is a fascinating compound that has garnered attention in various fields of chemistry and pharmacology due to its unique structure and potential applications. Here are some intriguing points about this compound:

  • Structural Complexity: The molecular architecture of this compound features a guanidine group, which is pivotal due to its involvement in biological systems. The guanidine moiety is often associated with nucleophilic properties, making it a significant player in biochemical reactions.
  • Pharmacological Potential: Compounds similar to 2-[2-[Phenyl(p-tolyl)methoxy]ethyl]guanidine are known for their biological activities, particularly in areas related to neurological research. They may impact neurotransmitter systems, which could lead to advancements in developing treatments for various neurological disorders.
  • Versatile Derivatives: The compound's structure allows for modifications, which can lead to the synthesis of various derivatives. This versatility opens up avenues for exploring different functional aspects and enhancing biological activity.
  • Receptor Interaction: The presence of the phenyl and tolane groups can facilitate interactions with various receptors in the body, making this compound a point of interest for drug design aimed at targeting specific pathways.
  • Research Significance: As a subject of study, compounds like this one are often examined in the context of lead discovery in medicinal chemistry. Researchers can evaluate their efficacy and safety profiles, contributing to the development of new therapeutic agents.

In summary, the exploration and understanding of 2-[2-[Phenyl(p-tolyl)methoxy]ethyl]guanidine are pivotal as they bridge the gap between chemical synthesis and potential real-world applications in medicine. The ongoing research into its properties and effects continues to prove the significance of such compounds in advancing scientific knowledge.