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2-(2-Piperidyl)ethanol

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Identification
Molecular formula
C7H15NO
CAS number
30483-72-6
IUPAC name
2-(2-piperidyl)ethanol
State
State

2-(2-Piperidyl)ethanol is usually a liquid at room temperature, but can sometimes be encountered as a solid if the ambient conditions allow.

Melting point (Celsius)
-23.00
Melting point (Kelvin)
250.15
Boiling point (Celsius)
223.00
Boiling point (Kelvin)
496.15
General information
Molecular weight
129.20g/mol
Molar mass
129.2020g/mol
Density
0.9790g/cm3
Appearence

2-(2-Piperidyl)ethanol is typically a colorless to light yellow liquid or solid that is most often found in a liquid state at room temperature. Its exact appearance can slightly vary depending on purity and specific conditions.

Comment on solubility

Solubility of 2-(2-piperidyl)ethanol

2-(2-piperidyl)ethanol, with the chemical formula C8H17NO, exhibits interesting solubility properties that are valuable for various applications. The compound is primarily soluble in:

  • Polar solvents: It shows good solubility in water due to the presence of the hydroxyl (-OH) group, which can interact favorably with water molecules.
  • Alcohols: Other polar organic solvents, like ethanol and methanol, facilitate its dissolution due to their similar polar characteristics.

However, when it comes to non-polar solvents:

  • Hydrophobic nature: 2-(2-piperidyl)ethanol is less soluble as the piperidine ring and hydrocarbon chain do not interact as effectively with non-polar solvents.

In summary, the solubility of 2-(2-piperidyl)ethanol is greatly influenced by the balance between its polar hydroxyl group and its larger hydrophobic character from the saturated piperidine moiety. The presence of these contrasting features makes it primarily soluble in polar environments, while exhibiting limited solubility in non-polar mediums.

Interesting facts

Interesting Facts about 2-(2-piperidyl)ethanol

2-(2-piperidyl)ethanol is a fascinating compound with various applications in both pharmaceutical research and organic synthesis. Here are some intriguing aspects of this chemical:

  • Structural Insights: This compound features a piperidine ring, which is a six-membered ring containing one nitrogen atom. Its unique structure contributes to its reactivity and interaction with biological targets.
  • Biological Relevance: Due to its piperidyl group, this compound is often investigated for its potential pharmacological properties, including its role as a precursor in the synthesis of various medications that target the central nervous system.
  • Synthetic Applications: 2-(2-piperidyl)ethanol is utilized in organic synthesis as a versatile building block. Its alcohol functional group enables numerous transformations, including oxidation and esterification, making it a vital reagent in the lab.
  • Medicinal Chemistry: Some derivatives of this compound have been studied for their potential to act as anxiolytics, antidepressants, or antihistamines, showcasing its importance in drug discovery and development.
  • Research Opportunities: The structure of 2-(2-piperidyl)ethanol allows chemists to explore modifications that could lead to the discovery of new therapeutic agents, thus perpetuating ongoing scientific inquiry.

As a student or scientist, exploring the nuances of such compounds not only fuels the quest for new knowledge but also encourages innovative approaches to solving real-world health challenges. The potential of 2-(2-piperidyl)ethanol serves as an excellent reminder of the intricate relationship between chemistry and biological activity.

Synonyms
1484-84-0
2-(2-Hydroxyethyl)piperidine
2-(piperidin-2-yl)ethanol
2-Piperidin-2-ylethanol
2-Piperidine ethanol
2-(2-Piperidinyl)ethanol
UNII-EHY6X8X6JQ
EHY6X8X6JQ
NSC 9261
NSC-9261
EINECS 216-059-2
AI3-36432
PTHDBHDZSMGHKF-UHFFFAOYSA-
EC 216-059-2
J133C
(+-)-2-PIPERIDINEETHANOL
inchi=1/c7h15no/c9-6-4-7-3-1-2-5-8-7/h7-9h,1-6h2
2-PIPERIDINEETHANOL
2-(Piperidin-2-Yl)Ethan-1-Ol
2-Ethanolpiperidine, 95%
DTXSID3044837
2-(2-piperidyl)ethan-1-ol
2-(HYDROXYETHYL)PIPERIDINE
(R)-(+)-Piperidine-2-Ethanol
2-piperidin-2-yl-ethanol
2-hydroxyethyl piperidine
2-Piperidineethanol, (S)-
2-piperidine-ethanol
Piperidine-2-ethanol
2(R/S)-(2-Hydroxyethyl)piperidine
MFCD00005989
MFCD08461072
MFCD08461073
2-piperidinethanol
NSC9261
2-Piperidineethanol; (+/-)-2-Piperidineethanol; 2-(2-Hydroxyethyl)piperidine; 2-(2-Piperidinyl)ethanol; 2-Piperidine-2-yl-ethanol; NSC 9261
(+/-)-2-piperidineethanol
(S)-2-(Piperidin-2-yl)ethanol;2-[(2S)-2-piperidyl]ethanol
2-(2-Piperidinyl)ethanol #
SCHEMBL214440
(R)-2-(2-Piperidyl)ethanol
(S)-2-(2-Piperidyl)ethanol
2-(2-hydroxyethyl)-piperidine
CHEMBL3188566
DTXCID1024837
2-Ethanolpiperidine, 95per cent
ALBB-021326
2(R,S)-(2-hydroxyethyl)piperidine
Tox21_301688
BBL027554
STK801836
AKOS000120680
AKOS016050704
CS-W001979
MB06302
SB41117
SB42942
SB42990
NCGC00256091-01
AS-14491
SY105723
SY111895
CAS-1484-84-0
2-Piperidineethanol, technical grade, 90%
DB-059028
H0736
EN300-21001
2-piperidine-ethanol;1-(2-Hydroxyethyl) piperidine
Q18611680
F2190-0335