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Tropacocaine

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Identification
Molecular formula
C13H19NO2
CAS number
536-33-4
IUPAC name
2-(2-piperidyl)ethyl 2-methylprop-2-enoate
State
State

At room temperature, Tropacocaine is in a crystalline solid state.

Melting point (Celsius)
49.00
Melting point (Kelvin)
322.15
Boiling point (Celsius)
305.20
Boiling point (Kelvin)
578.35
General information
Molecular weight
219.30g/mol
Molar mass
219.3010g/mol
Density
1.0564g/cm3
Appearence

Tropacocaine appears as a white, crystalline solid or powder. It is typically odorless and has a bitter taste.

Comment on solubility

Solubility of 2-(2-piperidyl)ethyl 2-methylprop-2-enoate

The solubility of 2-(2-piperidyl)ethyl 2-methylprop-2-enoate can be significantly influenced by various factors including its molecular structure and interactions with solvents. This compound, with its unique functional groups, exhibits the following solubility characteristics:

  • Polar and Non-Polar Solvents: The presence of the piperidyl group suggests that this compound may have a degree of polarity, which can enhance its solubility in polar solvents such as water and alcohols.
  • Hydrogen Bonding: The amine group in the piperidyl portion may engage in hydrogen bonding with water, possibly increasing solubility in aqueous solutions.
  • Hydrophobic Effects: The 2-methylprop-2-enoate moiety is more hydrophobic, which could limit solubility in highly polar solvents, yet might dissolve well in organic solvents like DMSO or ethanol.

Overall, the solubility behavior of 2-(2-piperidyl)ethyl 2-methylprop-2-enoate reflects a balance between its polar and non-polar characteristics. This complex interplay makes it essential to conduct empirical tests under specific conditions to determine the exact solubility profile of this compound.

Interesting facts

Interesting Facts about 2-(2-piperidyl)ethyl 2-methylprop-2-enoate

2-(2-piperidyl)ethyl 2-methylprop-2-enoate is a fascinating compound with numerous applications and attributes that make it noteworthy in the field of chemistry:

  • Chemical Structure: This compound features a unique structure that includes a piperidine ring, which is known for its significant contributions to medicinal chemistry. The presence of this cyclic amine allows for interesting interactions in biological systems.
  • Potential Biological Activity: Compounds featuring the piperidine moiety often exhibit a range of biological activities, including analgesic, antihistaminic, and antipsychotic effects, making them valuable in drug discovery and development.
  • Versatile Reactivity: The presence of the 2-methylprop-2-enoate group opens up numerous avenues for further chemical transformations. This characteristic significantly enhances its utility in synthetic organic chemistry.
  • Synthesis Methods: Various synthetic routes can lead to the formation of this compound, including the use of Michael additions or esterifications, allowing chemists to explore different pathways and improve yields.
  • Research Impact: The exploration of this compound, alongside derivatives of piperidine and acrylic acid esters, continues to inspire research aimed at discovering new pharmacological properties and improving existing synthetic methods.

In summary, 2-(2-piperidyl)ethyl 2-methylprop-2-enoate exemplifies how a simple change in structure can lead to vast implications in both synthetic and medicinal chemistry. This compound not only serves as a building block in various syntheses but also beckons scientists to delve deeper into its biologically relevant properties.

Synonyms
2-Piperidinoethyl methacrylate
2-piperidin-2-ylethyl 2-methylprop-2-enoate
Piperidylethyl methacrylate
beta-Piperidinoethyl methacrylate
2-(N-Piperidyl)ethyl methacrylate
2-(1-Piperidyl)ethyl methacrylate
beta-(N-Piperidyl)ethyl methacrylate
BRN 1282640
METHACRYLIC ACID, 2-PIPERIDINOETHYL ESTER
DTXSID90941130
2-Propenoic acid, 2-methyl-, 2-(1-piperidinyl)ethyl ester
2-(piperidin-2-yl)ethyl 2-methylprop-2-enoate