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Lidocaine hydrochloride

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Identification
Molecular formula
C18H28ClN2O2
CAS number
3737-95-9
IUPAC name
2-[(2-pyridin-1-ium-1-ylacetyl)amino]ethyl dodecanoate;chloride
State
State

Typically, lidocaine hydrochloride is encountered as a solid at room temperature, primarily as its crystalline powder form for pharmaceutical use.

Melting point (Celsius)
74.00
Melting point (Kelvin)
347.00
Boiling point (Celsius)
350.00
Boiling point (Kelvin)
623.00
General information
Molecular weight
271.80g/mol
Molar mass
271.7980g/mol
Density
1.0300g/cm3
Appearence

Lidocaine hydrochloride appears as a white or almost white crystalline powder. It is odorless, or almost odorless, and has a slightly bitter taste. The compound is often used in its powder form in various pharmaceutical formulations.

Comment on solubility

Solubility of 2-[(2-pyridin-1-ium-1-ylacetyl)amino]ethyl dodecanoate;chloride

The solubility of the compound 2-[(2-pyridin-1-ium-1-ylacetyl)amino]ethyl dodecanoate;chloride can be characterized by several important factors:

  • Polarity: This compound exhibits both polar and non-polar characteristics due to the presence of the pyridinium cation and the dodecanoate moiety. As a result, it is likely to have differing solubility in polar and non-polar solvents.
  • Solvent Dependence: It is anticipated that this compound is more soluble in polar solvents, such as water or methanol, compared to non-polar solvents. The polar nature from the pyridinium group promotes solubility in aqueous environments.
  • Temperature Influence: Similar to many organic compounds, solubility can increase with temperature. As the temperature rises, the kinetic energy of the molecules increases, potentially facilitating better solvation.
  • Chain Length Effect: The long dodecanoate chain may impede solubility in highly polar solvents, leading to an interesting balance where increased hydrophobic character may contribute to lower solubility in pure water.

In conclusion, the solubility behavior of 2-[(2-pyridin-1-ium-1-ylacetyl)amino]ethyl dodecanoate;chloride is influenced by its unique structure and environmental conditions, making it essential to assess solubility on a case-by-case basis in relevant solvent systems.

Interesting facts

Interesting Facts about 2-[(2-pyridin-1-ium-1-ylacetyl)amino]ethyl dodecanoate;chloride

The compound 2-[(2-pyridin-1-ium-1-ylacetyl)amino]ethyl dodecanoate;chloride is a fascinating molecule that blends organic and biochemical elements, making it an interesting subject of study in various fields. Here are some engaging points and facts about this compound:

  • Dual Functionality: This compound contains both pyridinium and dodecanoate components, allowing it to act as a surfactant and an antimicrobial agent. Its unique structure may lend itself to applications in drug delivery systems.
  • Pyridinium Influence: The presence of the pyridinium ring is significant because compounds featuring nitrogen-containing heterocycles are often utilized in medicinal chemistry. Pyridine derivatives, like this one, have been linked to various biological activities.
  • Biochemical Applications: With its capacity to influence membrane interactions, this compound could play a role in studies of cell biology, particularly concerning how substances cross cellular membranes.
  • Potential in Drug Design: The unique structural characteristics provide a useful scaffold for designing new pharmacological agents. Such modifications could lead to a range of targeted therapies.

This compound merges the realms of organic synthesis and medicinal application, showcasing the importance of interdisciplinary approaches in science. As with many compounds, understanding the comprehensive roles and interactions of its components can lead to exciting discoveries in both fundamental and applied chemistry.

Synonyms
LAPYRIUM CHLORIDE
6272-74-8
Lapirium chloride
Emcol E-607
Lapyrium chloride [USAN]
NSC-33659
Caswell No. 519
Lapirii chloridum [INN-Latin]
Lapirium chloride [INN]
N-(Lauroylcolaminoformylmethyl)pyridinium chloride
Cloruro de lapirio [INN-Spanish]
Chlorure de lapirium [INN-French]
EINECS 228-464-1
N-(Acylcolaminoformylmethyl)pyridinum chloride
EPA Pesticide Chemical Code 069131
N'-Lauroylcolaminoformylmethyl pyridinium chloride
N-(Colaminoformylmethyl)pyridinium chloride laurate
UNII-732T8851QH
Lapirium chloride (INN)
Lapyrium chloride (USAN)
732T8851QH
N-(Lauroyl colamino formylmethyl)pyridinium chloride
Pyridinium, 1-(2-oxo-2-((2-((1-oxododecyl)oxy)ethyl)amino)ethyl)-, chloride
LAPYRIUM CHLORIDE [MI]
DTXSID5042085
E-607
N-((N-(2-Dodecanoyloxyethyl)carbamoyl)methyl)pyridinium chloride
LAPIRIUM CHLORIDE [WHO-DD]
1-(((2-Hydroxyethyl)carbamoyl)methyl)pyridinium chloride laurate (ester)
NSC33659
Pyridinium, 1-(2-oxo-2-((2-((1-oxododecyl)oxy)ethyl)-amino)ethyl)-, chloride
N-(Lauryl colamino formyl methyl) pyridinium chloride
LAPYRIUM CHLORIDE [ORANGE BOOK]
1-(2-Hydroxyethyl)carbamoyl methyl pyridinium chloride laurate
VIRAC REX COMPONENT LAPYRIUM CHLORIDE
Pyridinium, 1-(2-hydroxyethylcarbamoylmethyl)-, chloride, dodecanoate
1-(2-Oxo-2-((2-((1-oxododecyl)oxy)ethyl)amino)ethyl)pyridinium chloride
Pyridinium, 1-(((2-hydroxyethyl)carbamoyl)methyl)-, chloride, laurate (ester)
Lapirii chloridum (INN-Latin)
Cloruro de lapirio (INN-Spanish)
Chlorure de lapirium (INN-French)
1-((2-DODECANOYLOXYETHYLCARBAMOYL)METHYL)PYRIDINIUM CHLORIDE
1-[[(2-Hydroxyethyl)carbamoyl]methyl]pyridinium chloride laurate (ester)
Pyridinium, 1-[2-oxo-2-[[2-[(1-oxododecyl)oxy]ethyl]amino]ethyl]-, chloride
N-[[N-(2-Dodecanoyloxyethyl)carbamoyl]methyl]pyridinium chloride
DTXCID3022085
LAPYRIUM CHLORIDE [INCI]
LAPYRIUM CHLORIDE COMPONENT OF VIRAC REX
Pyridinium, 1-(((2-hydroxyethyl)carbamoyl)methyl)-, chloride, laurate (ester) (8CI)
1-(2-((2-(Dodecanoyloxy)ethyl)amino)-2-oxoethyl)pyridin-1-ium chloride
Cloruro de lapirio
Chlorure de lapirium
Lapyrium (chloride)
Emcol E 607L; Lapirium chloride
2-[(2-pyridin-1-ium-1-ylacetyl)amino]ethyl dodecanoate;chloride
Lapirii chloridum
Lapyrium Cl
Emcol E607
Emcol E 607
SCHEMBL138621
CHEMBL1201787
Pyridinium, chloride, dodecanoate
2-[(2-pyridin-1-ium-1-ylacetyl)amino]ethyl dodecanoate,chloride
WLN: T6KJ A1VM2OV11 &G
AKOS015896197
Pyridinium, chloride, laurate (ester)
HY-107996
CS-0031158
NS00080985
D04669
EN300-19767850
N-(Lauroylcolamenoformylmethyl)pyridinium chloride
N-(Lauroylcolamino formylmethyl)pyridinium chloride
Q27266118
1-({[2-(dodecanoyloxy)ethyl]carbamoyl}methyl)pyridin-1-ium chloride
Lauric acid, ester with 1-[[(2-hydroxyethyl)carbamoyl]methyl]pyridinium chloride
Pyridinium, 1-(2-oxo-2-((2-((1-oxododecyl)oxy)ethyl)amino)ethyl)-, chloride (1:1)