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2-[2-[(pyridine-4-carbonylhydrazono)methyl]phenoxy]acetic acid

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Identification
Molecular formula
C14H13N3O4
CAS number
78026-39-6
IUPAC name
2-[2-[(pyridine-4-carbonylhydrazono)methyl]phenoxy]acetic acid
State
State

At room temperature, 2-[2-[(pyridine-4-carbonylhydrazono)methyl]phenoxy]acetic acid is in a solid state, typically encountered as a powder or crystalline solid.

Melting point (Celsius)
216.50
Melting point (Kelvin)
489.70
Boiling point (Celsius)
491.60
Boiling point (Kelvin)
764.80
General information
Molecular weight
271.27g/mol
Molar mass
271.2660g/mol
Density
1.3318g/cm3
Appearence

2-[2-[(Pyridine-4-carbonylhydrazono)methyl]phenoxy]acetic acid appears as a pale yellow to yellow crystalline powder. It is often used in research laboratories and may present in powdered form for experimental applications.

Comment on solubility

Solubility of 2-[2-[(pyridine-4-carbonylhydrazono)methyl]phenoxy]acetic acid

The solubility of 2-[2-[(pyridine-4-carbonylhydrazono)methyl]phenoxy]acetic acid plays a critical role in its application in various chemical and biological processes. Generally, this compound has exhibited moderate solubility characteristics in different solvents, which can be summarized as follows:

  • Organic Solvents: The compound is typically soluble in a range of organic solvents due to its hydrophobic phenyl and pyridine moieties.
  • Aqueous Solubility: Its solubility in water tends to be lower, which is common for many acid-functional organic compounds. This hint suggests that the carboxylic acid group might not be fully ionized under neutral pH conditions.
  • pH Influence: The solubility is highly influenced by pH; at lower pH values, the carboxylic acid can become protonated, potentially decreasing solubility.

Due to these factors, the solubility of this compound can vary significantly based on environmental conditions and solvent choice. As a rule of thumb, it is always advisable to conduct solubility tests in the specific conditions intended for use to ensure optimal performance.

In summary, understanding the solubility properties not only enhances the application potential of 2-[2-[(pyridine-4-carbonylhydrazono)methyl]phenoxy]acetic acid but also promotes the safe handling and implementation in various chemical protocols.

Interesting facts

Interesting Facts about 2-[2-[(pyridine-4-carbonylhydrazono)methyl]phenoxy]acetic acid

This fascinating compound does not only present an intriguing chemical structure but also holds significant potential in various fields. Here are some engaging facts that highlight its importance:

  • Pharmaceutical Applications: The compound is of great interest in medicinal chemistry. Its unique structure lends itself to the development of new pharmaceuticals, particularly in the realm of anti-inflammatory and anti-cancer agents.
  • Mechanism of Action: The presence of the pyridine ring enhances the compound's ability to interact with biological receptors. This interaction may modify biological pathways, making it a candidate for further research in drug development.
  • Research Use: This compound allows researchers to explore complex chemical behaviors as it combines a hydrazone moiety with an acetic acid group. Such combinations can lead to unexpected chemical properties and biological activities.
  • Structure-Activity Relationship (SAR): Scientists are particularly interested in the structure-activity relationship of this compound. By modifying different substituents, they can study how changes impact biological activity, leading to highly effective derivatives.
  • Applications in Agriculture: Beyond medicinal use, similar compounds have shown promise in agricultural chemistry as herbicides or fungicides, thus driving interest in potential agricultural applications for this compound.

In essence, 2-[2-[(pyridine-4-carbonylhydrazono)methyl]phenoxy]acetic acid exemplifies how small changes in chemical structure can lead to significant outcomes in various fields. As research continues, it may unlock new pathways to combat diseases and improve agricultural practices.

Synonyms
Cpd 377;Isonicophen;Phenoxalid
2-[2-[(pyridine-4-carbonylhydrazinylidene)methyl]phenoxy]acetic acid
orb1703838
DTXSID90860115
AKOS030746754
NS00123426
(2-{[2-(Pyridine-4-carbonyl)hydrazinylidene]methyl}phenoxy)acetic acid