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2-(2-pyridyl)benzothiazole

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Identification
Molecular formula
C12H8N2S
CAS number
34937-00-3
IUPAC name
2-(2-pyridyl)-1,3-benzothiazole
State
State

At room temperature, 2-(2-pyridyl)benzothiazole is in a solid state, specifically a crystalline form.

Melting point (Celsius)
153.00
Melting point (Kelvin)
426.15
Boiling point (Celsius)
390.00
Boiling point (Kelvin)
663.15
General information
Molecular weight
210.27g/mol
Molar mass
210.2720g/mol
Density
1.3240g/cm3
Appearence

2-(2-pyridyl)benzothiazole typically appears as a yellow crystalline solid. Its crystalline structure can vary depending on the specific conditions under which it was synthesized.

Comment on solubility

Solubility of 2-(2-pyridyl)-1,3-benzothiazole

The solubility of 2-(2-pyridyl)-1,3-benzothiazole can be influenced by several factors, including temperature, solvent, and molecular structure. This compound is known to exhibit specific solubility behaviors in various solvents. Here are some key points to consider:

  • Polar Solvents: It has limited solubility in polar solvents such as water due to the presence of hydrophobic aromatic rings.
  • Organic Solvents: It tends to be more soluble in organic solvents, particularly in those that are non-polar or slightly polar, like ethyl acetate and chloroform.
  • Temperature Effects: Elevated temperatures can enhance the solubility of 2-(2-pyridyl)-1,3-benzothiazole due to increased molecular motion, leading to better dissolution in chosen solvents.

In summary, while this compound may not dissolve well in aqueous environments, it presents a greater affinity for organic solvents, emphasizing the importance of solvent choice in experiments and applications involving 2-(2-pyridyl)-1,3-benzothiazole. It is crucial to consider the solubility profile for effective usage in practical scenarios.

Interesting facts

Interesting Facts about 2-(2-pyridyl)-1,3-benzothiazole

2-(2-pyridyl)-1,3-benzothiazole is a fascinating organic compound that captures the attention of chemists for several reasons.

1. Unique Structure

This compound features a distinctive molecular structure that combines both a pyridine ring and a benzothiazole moiety. This arrangement results in interesting electronic properties, which can lead to varied applications:

  • Fluorescence: The compound has been noted for its fluorescent properties, making it useful in photonics.
  • Drug Development: Its structure is often explored in the synthesis of pharmaceuticals due to potential biological activities.

2. Biological Significance

Research has indicated that derivatives of 2-(2-pyridyl)-1,3-benzothiazole exhibit potential as:

  • Antimicrobial agents: Showing effectiveness against various microbial strains.
  • Anticancer properties: Some studies suggest it could inhibit tumor growth.

This makes it a compound of significant interest in medicinal chemistry.

3. Coordination Chemistry

Another remarkable aspect of this compound is its capability to act as a ligand. It can form complexes with various metal ions, which can enhance the compound's properties and lead to:

  • Enhanced catalytic activity: Useful in various chemical reactions.
  • Coordination with transition metals: Creating new materials with exciting features.

4. Synthesis Techniques

The pathways to synthesize 2-(2-pyridyl)-1,3-benzothiazole are diverse, often involving:

  • Condensation reactions: Which can be performed under mild conditions.
  • Multicomponent reactions: Leading to high yields of the desired compound.

The versatility in its synthesis reflects the compound's importance in organic chemistry.

Overall, 2-(2-pyridyl)-1,3-benzothiazole serves as a perfect illustration of how chemical compounds can possess multifaceted roles in science, spanning applications from drug design to advanced materials. As scientists continue to explore its properties and potential, this compound's story is far from over.

Synonyms
716-80-3
2-(pyridin-2-yl)benzo[d]thiazole
BENZOTHIAZOLE, 2-(2-PYRIDYL)-
Benzothiazole, 2-(2-pyridinyl)-
2-(Pyridin-2-yl)benzothiazole
2-(pyridin-2-yl)-1,3-benzothiazole
2-pyridin-2-yl-1,3-benzothiazole
2-(2-Pyridinyl)benzothiazole
Benzothiazole, 2-(2-pyridinyl)- (9CI)
MLS000736697
NSC-62611
2-(2-pyridyl)benzothiazole
2-(alpha-Pyridyl)benzothiazole
NSC 62611
BRN 0151408
NSC62611
NCIOpen2_002777
TZ939HAJ6T
2-(2'-pyridyl)benzothiazole
4-27-00-07184 (Beilstein Handbook Reference)
MLS000057976
SCHEMBL221431
CHEMBL1379011
DTXSID00221834
2-(.alpha.-Pyridyl)benzothiazole
XSWCYXIBEZMXMM-UHFFFAOYSA-N
HMS2381H21
HMS2780N08
STL326898
AKOS001044154
CCG-107038
HS-5970
SMR000063020
SMR000446921
DB-274721
CS-0210293
F88112
Z50128913