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Trospium chloride

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Identification
Molecular formula
C25H30ClNO3
CAS number
10405-02-4
IUPAC name
2-[2-tert-butyl-1-(2-ethylphenyl)cyclohexoxy]ethyl-dimethyl-ammonium;chloride
State
State

At room temperature, trospium chloride is in a solid state. It is typically available as a crystalline powder for pharmaceutical use.

Melting point (Celsius)
222.00
Melting point (Kelvin)
495.15
Boiling point (Celsius)
138.00
Boiling point (Kelvin)
411.15
General information
Molecular weight
427.03g/mol
Molar mass
427.0250g/mol
Density
1.1750g/cm3
Appearence

Trospium chloride appears as a white to off-white crystalline powder. It is generally odorless.

Comment on solubility

Solubility of 2-[2-tert-butyl-1-(2-ethylphenyl)cyclohexoxy]ethyl-dimethyl-ammonium;chloride

The solubility of the compound 2-[2-tert-butyl-1-(2-ethylphenyl)cyclohexoxy]ethyl-dimethyl-ammonium chloride is influenced by several key factors:

  • Polarity: Due to its quaternary ammonium structure, the compound tends to exhibit a polar character, which can enhance its solubility in polar solvents, especially water.
  • Ionization: As it is a quaternary ammonium salt, upon dissolution in water, it disassociates to form dimethylammonium and chloride ions, potentially increasing its solubility due to the favorable interactions of these ions with water molecules.
  • Temperature Dependency: Like many ionic compounds, its solubility may increase with temperature, allowing for greater dissolution in hotter solutions.
  • Hydrophobic Groups: The compound contains hydrophobic components such as the tert-butyl and cyclohexyl structures, which could affect its overall solubility by making it less soluble in purely aqueous environments.

As a result, while the compound may be soluble in water to some extent due to its ionic nature, the presence of bulky hydrophobic groups suggests a more complex solubility profile, likely favoring a higher solubility in organic solvents or mixtures that also possess polar characteristics.

In conclusion, the solubility of 2-[2-tert-butyl-1-(2-ethylphenyl)cyclohexoxy]ethyl-dimethyl-ammonium chloride can be summarized as being generally favorable in polar environments, with considerations for temperature and solvent composition resulting in varied solubility outcomes.

Interesting facts

Interesting Facts about 2-[2-tert-butyl-1-(2-ethylphenyl)cyclohexoxy]ethyl-dimethyl-ammonium;chloride

This compound, commonly referred to as a quaternary ammonium salt, has intriguing properties and applications that make it a subject of interest in various scientific fields. Here are some fascinating insights:

  • Quaternary Ammonium Compounds (QACs): This compound belongs to the class of QACs, which are known for their ability to act as surfactants and antimicrobial agents. They are widely used in personal care products, disinfectants, and preservatives.
  • Application Potential: Given its amphiphilic nature, it could potentially serve in formulating emulsions or as a stabilizer in various chemical processes.
  • Biochemical Interaction: Its specific structure, with a tert-butyl group and a cyclohexoxy moiety, suggests it can interact with biological membranes, which opens avenues for pharmaceutical research, particularly in drug delivery systems.
  • Insight from Structure: The presence of a dimethylammonium group signifies that this compound may possess cationic characteristics, which can be instrumental in binding negatively charged biological substrates or surfaces.
  • Environmental Impact: Understanding its biodegradability and ecological footprint is crucial, as many QACs have raised concerns regarding their persistence in aquatic environments.

As quoted by a notable chemist, “The beauty of chemistry lies in the intricate dance between structure and function.” This compound exemplifies this principle, where its unique structural features confer distinct properties that can be harnessed for innovative applications.

Overall, 2-[2-tert-butyl-1-(2-ethylphenyl)cyclohexoxy]ethyl-dimethyl-ammonium;chloride typifies the vast potential of chemical compounds to impact both technology and health care, warranting further exploration and research.

Synonyms
Ethylamine, 2-((2-tert-butyl-1-(o-ethylphenyl)cyclohexyl)oxy)-N,N-dimethyl-, hydrochloride
2-((2-tert-Butyl-1-(o-ethylphenyl)cyclohexyl)oxy)-N,N-dimethylethylamine hydrochloride
14602-45-0