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Thiophen-2-ylacetic acid

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Identification
Molecular formula
C6H6O2S
CAS number
14755-41-0
IUPAC name
2-(2-thienyl)acetic acid
State
State

At room temperature, Thiophen-2-ylacetic acid is typically found in a solid state. It is often encountered as a crystalline powder.

Melting point (Celsius)
73.00
Melting point (Kelvin)
346.15
Boiling point (Celsius)
221.80
Boiling point (Kelvin)
494.95
General information
Molecular weight
140.17g/mol
Molar mass
140.1740g/mol
Density
1.2780g/cm3
Appearence

Thiophen-2-ylacetic acid appears as a crystalline solid. It can exhibit a white to light yellow color depending on its purity and form. The compound is somewhat hygroscopic and can absorb moisture from the environment, which may affect its appearance.

Comment on solubility

Solubility Characteristics of 2-(2-thienyl)acetic Acid

2-(2-thienyl)acetic acid, with its unique structure, presents intriguing solubility properties that are heavily influenced by its functional groups and aromatic nature. This compound is known to be:

  • Slightly soluble in water: Its solubility in water is limited, primarily due to the hydrophobic character of the thienyl ring.
  • Soluble in organic solvents: 2-(2-thienyl)acetic acid is more readily soluble in non-polar to moderately polar organic solvents, such as ethanol, methanol, and dichloromethane.

These solubility traits may be summarized as:

  1. Low aqueous solubility
  2. Higher solubility in organic solvents

In practical applications, the solubility of 2-(2-thienyl)acetic acid is significant for its use in organic synthesis and pharmaceutical formulations. Understanding these solubility characteristics can be crucial when considering its reactivity and the formation of derivatives. According to solubility principles, “like dissolves like”; thus the thienyl presence primarily dictates its behavior within various solvent environments.

Interesting facts

Interesting Facts about 2-(2-thienyl)acetic Acid

2-(2-thienyl)acetic acid is a captivating compound that exhibits unique properties and applications in various fields. This molecule is notable for its aromatic structure and functional groups, making it a significant subject of study in organic chemistry.

Chemical Significance

  • Structural Characteristics: The presence of a thiophene ring, characteristic of this compound, imparts exceptional stability and unique reactivity.
  • Biological Activity: Compounds with thiophene rings often exhibit interesting biological activities, including anti-inflammatory and antimicrobial properties.
  • Versatile Intermediates: It can act as a precursor or intermediate in the synthesis of various pharmaceuticals, agrochemicals, and other functional materials.

Applications

  • Pharmaceutical Industry: Its derivatives are explored for potential therapeutic applications, showcasing the importance of structure-activity relationships in drug design.
  • Material Science: Used in the synthesis of polymers and materials that exhibit enhanced electrical conductivity or optical properties.
  • Research Tool: Often employed in chemical research as a building block for more complex organic architectures.

As noted by chemists, "The study of compounds like 2-(2-thienyl)acetic acid not only enhances our understanding of chemical behavior but also opens doors to innovative materials and therapeutic solutions." This highlight emphasizes the compound's pivotal role in advancing both fundamental and applied chemistry.

In conclusion, whether you're a student or a seasoned chemist, 2-(2-thienyl)acetic acid represents a fascinating intersection of structure, reactivity, and application in chemistry.

Synonyms
2-Thiopheneacetic acid
1918-77-0
2-(thiophen-2-yl)acetic acid
2-Thienylacetic acid
THIOPHENE-2-ACETIC ACID
2-(2-thienyl)acetic acid
2-thiophen-2-ylacetic acid
(Thien-2-yl)acetic acid
A8S4F49X7A
CHEBI:45807
EINECS 217-639-8
DTXSID5062059
DTXCID3036024
217-639-8
Thiopheneacetic acid
MFCD00005458
thiophen-2-ylacetic acid
2-THIOPHENE ACETIC ACID
69492-74-6
thiophen-2-yl-acetic acid
2-THENYLACETIC ACID
thienylactic acid
thienylacetic acid
2-thiopheneacetic
thiol acetic acid
1ajq
2-(2-Thienyl)acetic Acid; 2-(Thien-2-yl)acetic Acid; 2-(Thiophen-2-yl)acetic Acid; 2-Thienylacetic Acid; 2-Thienylethanoic Acid; Thiophen-2-ylacetic Acid
Thiophene acetic acid
2-thienyl-acetic acid
thien-2-ylacetic acid
2-carboxymethylthiofuran
2-thiophenyl acetic acid
thiophen-2-yl acetic acid
Epitope ID:116203
UNII-A8S4F49X7A
2-(2-thienyl) acetic acid
2-(thiophen-2-yl)aceticacid
BIDD:GT0423
SCHEMBL621289
2-Thiopheneacetic acid, 98%
THIOPHEN-2-ACETIC ACID
acetic acid, 2-(2-thienyl)-
BCP30947
STL164313
AKOS000118998
CS-W001142
FT71214
HY-W001142
PB27359
PS-5326
DB-044778
NS00026257
T0217
EN300-19262
C02595
P10011
AI-942/25034211
Q27104558
F2191-0032
Z104473344
2-Thienylacetic acid;2-(thiophen-2-yl)acetic acid;Thiopheneacetic acid