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Cloperastine Hydrochloride

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Identification
Molecular formula
C23H29Cl2NO2
CAS number
3703-76-2
IUPAC name
2-[2,2-bis(4-chlorophenyl)-1,3-dioxolan-4-yl]piperidin-1-ium;chloride
State
State

At room temperature, Cloperastine Hydrochloride is a solid. It is stored in a dry place and typically handled in its crystalline form.

Melting point (Celsius)
107.40
Melting point (Kelvin)
380.55
Boiling point (Celsius)
305.00
Boiling point (Kelvin)
578.15
General information
Molecular weight
452.88g/mol
Molar mass
452.8750g/mol
Density
1.2900g/cm3
Appearence

Cloperastine Hydrochloride typically appears as a white or off-white crystalline powder. Its appearance is uniform and lacks any coloration or significant impurities.

Comment on solubility

Solubility of 2-[2,2-bis(4-chlorophenyl)-1,3-dioxolan-4-yl]piperidin-1-ium; chloride

The solubility of 2-[2,2-bis(4-chlorophenyl)-1,3-dioxolan-4-yl]piperidin-1-ium; chloride in various solvents can be influenced by several factors. Below are some key points regarding its solubility:

  • General Characteristics: The presence of quaternary ammonium groups often enhances solubility in polar solvents.
  • Polar Solvents: This compound is expected to have good solubility in polar solvents such as water and ethanol due to the ionic nature of the chloride component.
  • Non-Polar Solvents: While the chlorophenyl groups suggest limited solubility in non-polar solvents, some degree of solubility may still be observed.
  • Temperature Dependence: Like many ionic compounds, solubility may increase with temperature, highlighting the importance of thermal conditions.

In summary, 2-[2,2-bis(4-chlorophenyl)-1,3-dioxolan-4-yl]piperidin-1-ium; chloride is likely to be more soluble in polar solvents, possibly showing limited solubility in non-polar environments. The interplay between its ionic and aromatic characteristics plays a critical role in determining its solubility behavior.

Interesting facts

Interesting Facts about 2-[2,2-bis(4-chlorophenyl)-1,3-dioxolan-4-yl]piperidin-1-ium;chloride

This intriguing compound is recognized for its notable structural features and potential applications. Here are some interesting insights:

  • Complex Structure: The compound integrates a piperidine ring, which is known for its role in various pharmacological activities, with a dioxolane moiety that adds to its chemical diversity.
  • Pharmacological Significance: 2-[2,2-bis(4-chlorophenyl)-1,3-dioxolan-4-yl]piperidin-1-ium;chloride may exhibit interesting biological properties due to its unique molecular configuration, making it a subject of interest in medicinal chemistry.
  • Environmental Stability: The chlorinated phenyl groups present in the structure may offer enhanced stability against metabolic degradation, which is crucial for developing effective therapeutics.
  • Designing Aids: This compound is often utilized in drug design and discovery, where its stability and biological effects can pave the way for new medicinal applications.
  • Research Applications: Researchers are continuously exploring the potential of such compounds in treating various diseases, particularly in developing anti-inflammatory and anti-cancer agents.

As a combination of structural complexity and potential therapeutic benefits, 2-[2,2-bis(4-chlorophenyl)-1,3-dioxolan-4-yl]piperidin-1-ium;chloride demonstrates the fascinating interplay between chemical properties and biological functions.

Synonyms
2,2-Bis(p-chlorophenyl)-4-(2-piperidyl)-1,3-dioxolane hydrochloride
7457-29-6
1,3-DIOXOLANE, 2,2-BIS(p-CHLOROPHENYL)-4-(2-PIPERIDYL)-, HYDROCHLORIDE