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Benzydamine hydrochloride

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Identification
Molecular formula
C20H26ClNO3
CAS number
3543-75-7
IUPAC name
2-[2,2-bis(4-methoxyphenyl)-1,3-dioxolan-4-yl]piperidin-1-ium;chloride
State
State

Benzydamine hydrochloride is in solid state at room temperature. It typically comes in the form of powder, which is highly soluble in water, making it useful in various medicinal formulations, particularly in oral and topical applications.

Melting point (Celsius)
167.50
Melting point (Kelvin)
440.70
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
423.97g/mol
Molar mass
423.9660g/mol
Density
1.1900g/cm3
Appearence

Benzydamine hydrochloride appears as a white crystalline powder. It is odorless and has a characteristic bitter taste. The compound is often used in its salt form for pharmaceutical applications, which contributes to its stability and solubility in aqueous solutions.

Comment on solubility

Solubility of 2-[2,2-bis(4-methoxyphenyl)-1,3-dioxolan-4-yl]piperidin-1-ium;chloride

The solubility of 2-[2,2-bis(4-methoxyphenyl)-1,3-dioxolan-4-yl]piperidin-1-ium;chloride is influenced by several structural features of the compound. Given its unique piperidinium structure, this compound can exhibit interesting solubility characteristics:

  • Ionic Nature: The presence of the chloride ion implies that the compound is likely soluble in polar solvents, especially water, due to its ionic character.
  • Hydrophobic Regions: The extensive aromatic substituents (4-methoxyphenyl groups) might lead to reduced solubility in purely aqueous environments, affecting interactions with water molecules.
  • Solvent Dependence: The compound can potentially dissolve in a variety of organic solvents, given its complex structure. Solubility may vary significantly in solvents such as ethanol, methanol, and DMSO.

In general, one might expect that this compound could demonstrate a certain degree of Amphipathicity—capable of interacting with both polar and nonpolar solvents. Therefore, assessing its solubility in various media is crucial for understanding its chemical behavior and potential applications in medicinal chemistry.

Interesting facts

Interesting Facts about 2-[2,2-bis(4-methoxyphenyl)-1,3-dioxolan-4-yl]piperidin-1-ium; chloride

The compound 2-[2,2-bis(4-methoxyphenyl)-1,3-dioxolan-4-yl]piperidin-1-ium; chloride showcases intriguing features that draw the attention of chemists and materials scientists alike. Here are some noteworthy points:

  • Unique Structure: This molecule combines elements of both piperidine and dioxolane, enhancing its potential applications in various fields, particularly in medicinal chemistry.
  • Pharmacological Potential: The presence of the piperidin-1-ium group suggests that it may exhibit interesting biological activity, making it a candidate for further research in drug development.
  • Electron-Donating Groups: The inclusion of the 4-methoxyphenyl groups enhances the electron-donating capabilities of the compound, potentially affecting its reactivity and interactions with other molecules.
  • Versatility: Compounds featuring dioxolane structures are often versatile intermediates, leading to multifunctional materials which can be useful in organic synthesis or as polymers.

As a unique ionic compound with a chloride anion, 2-[2,2-bis(4-methoxyphenyl)-1,3-dioxolan-4-yl]piperidin-1-ium; chloride intrigues researchers not only for its chemical architecture but also for the opportunities it may present in material science and pharmacology. The compound emphasizes how intricate structural features can lead to a myriad of functional potentials, making it a significant topic of study in contemporary chemistry.

"Understanding the symbiosis between structure and function is at the heart of chemical innovation."
This quote encapsulates the essence of exploring compounds like this one, where each atom and bond contributes to the overall behavior and properties.

Synonyms
alpha-2,2-Bis(p-methoxyphenyl)-4-(2-piperidyl)-1,3-dioxolane hydrochloride
1,3-DIOXOLANE, 2,2-BIS(p-METHOXYPHENYL)-4-(2-PIPERIDYL)-, HYDROCHLORIDE, alpha-
7457-32-1