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Carvedilol

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Identification
Molecular formula
C24H26N2O4
CAS number
72956-09-3
IUPAC name
2-(2,3-dihydro-1,4-benzodioxin-3-yl)-1-(2-methoxyethylamino)propan-2-ol
State
State

At room temperature, carvedilol is commonly found in a solid state. It is manufactured in powder form, which is then often compressed into tablet form for pharmaceutical use.

Melting point (Celsius)
114.00
Melting point (Kelvin)
387.15
Boiling point (Celsius)
422.00
Boiling point (Kelvin)
695.15
General information
Molecular weight
406.47g/mol
Molar mass
406.4740g/mol
Density
1.2508g/cm3
Appearence

Carvedilol is a white to almost white powder. It is characterized by its crystalline structure which can appear slightly off-white depending on purity and humidity conditions.

Comment on solubility

Solubility Characteristics

The compound 2-(2,3-dihydro-1,4-benzodioxin-3-yl)-1-(2-methoxyethylamino)propan-2-ol, with its intricate structure, exhibits notable solubility properties due to its functional groups and polarity.

Factors Affecting Solubility

Several factors contribute to the solubility of this compound, including:

  • Polarity: The presence of hydroxyl (-OH) and amino (-NH) groups enhances polarity, allowing for better solvation in polar solvents like water.
  • Hydrogen Bonding: The ability to form hydrogen bonds with solvent molecules facilitates dissolution, especially in protic solvents.
  • Substituent Effects: The methoxyethylamine group adds to the overall solubility profile by providing additional interaction sites.

Solubility in Different Solvents

This compound has varying degrees of solubility, notably:

  • In Water: Likely to be soluble owing to its polar functional groups.
  • In Organic Solvents: Moderate solubility can be expected in non-polar solvents, although the efficiency may be lower due to the polar characteristics of the compound.

In summary, the solubility of 2-(2,3-dihydro-1,4-benzodioxin-3-yl)-1-(2-methoxyethylamino)propan-2-ol is significantly influenced by its molecular structure. As a rule of thumb, "like dissolves like," so its solubility in solvents will vary based on the solvent's polarity and ability to interact with the compound's functional groups.

Interesting facts

Interesting Facts about 2-(2,3-dihydro-1,4-benzodioxin-3-yl)-1-(2-methoxyethylamino)propan-2-ol

This compound is a fascinating example of how structural complexity in organic chemistry can lead to diverse properties and potential biological activities. Known for its intricate molecular framework, it contains a benzodioxin component which is notable for its presence in various pharmaceutical compounds.

Key Structural Features:

  • Benzodioxin Ring: The compound features a fused dioxin and benzene ring, which is crucial in many medicinal chemistry applications.
  • Amino Alcohol: The presence of an amino group on the propanol backbone allows for the potential of various interactions in biological systems.
  • Ether Functionality: The methoxyethyl group introduces interesting characteristics related to solubility and reactivity.

Its unique structure lends the compound a number of intriguing properties:

  • Pharmacological Potential: Compounds containing benzodioxin rings have been investigated for various pharmacological effects, including anti-inflammatory and analgesic activities.
  • Biological Activity: The amino and hydroxyl groups can participate in hydrogen bonding, influencing the compound's binding affinity to different biological receptors.
  • Design Versatility: The molecular structure makes it a candidate for modifications aimed at optimizing efficacy in drug design.

Interestingly, researchers have pointed out that such molecules act as promising candidates in the search for new therapeutic agents. According to one study, "the complexity of the benzodioxin core allows for unique interactions, paving the way for innovation in medicinal chemistry."

Inevitably, this complex compound exemplifies how chemistry is at the forefront of developing new solutions in medicine, allowing scientists to explore myriad pathways in drug discovery.

Synonyms
BRN 1386897
3181 I.S.
13627-86-6
alpha-(((2-Methoxyethyl)amino)methyl)-alpha-methyl-1,4-benzodioxan-2-methanol
1,4-BENZODIOXAN-2-METHANOL, alpha-(((2-METHOXYETHYL)AMINO)METHYL)-alpha-METHYL-
2-(1-Idrossi-2-metil-2-(beta-metossietilammino))etil-1,4-benzodiossano [Italian]
2-(1-Idrossi-2-metil-2-(beta-metossietilammino))etil-1,4-benzodiossano
DTXSID30929316
2-(2,3-Dihydro-1,4-benzodioxin-2-yl)-1-[(2-methoxyethyl)amino]propan-2-ol