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Metoprolol

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Identification
Molecular formula
C15H25NO3
CAS number
37350-58-6
IUPAC name
2-(2,3-dihydro-1,4-benzodioxin-3-yl)-1-(4-methoxybutylamino)propan-2-ol
State
State

Metoprolol is typically in a solid state at room temperature.

Melting point (Celsius)
120.00
Melting point (Kelvin)
393.15
Boiling point (Celsius)
352.30
Boiling point (Kelvin)
625.45
General information
Molecular weight
267.36g/mol
Molar mass
267.3640g/mol
Density
1.1000g/cm3
Appearence

Metoprolol is a white, crystalline powder that is very soluble in water and freely soluble in ethanol. It is usually encountered in its salt form, metoprolol tartrate or metoprolol succinate, which ensures better solubility and absorption.

Comment on solubility

Solubility of 2-(2,3-dihydro-1,4-benzodioxin-3-yl)-1-(4-methoxybutylamino)propan-2-ol

The solubility of 2-(2,3-dihydro-1,4-benzodioxin-3-yl)-1-(4-methoxybutylamino)propan-2-ol in various solvents can be influenced by several factors. Understanding these can help in predicting its behavior in different environments.

  • Polar vs. Non-Polar Solvents: Compounds with polar functional groups tend to be more soluble in polar solvents (e.g., water, alcohols), while non-polar solvents (e.g., hydrocarbons) are better for non-polar compounds. The presence of a methoxy group in this compound suggests a degree of polarity.
  • Hydrogen Bonding: The ability to form hydrogen bonds greatly enhances solubility. If this compound can participate in hydrogen bonding with solvent molecules, its solubility in polar solvents will be increased.
  • Temperature Effects: Generally, solubility increases with temperature. This means that dissolving this compound in warm solvents might yield better results than in cold solvents.

In conclusion, the solubility of 2-(2,3-dihydro-1,4-benzodioxin-3-yl)-1-(4-methoxybutylamino)propan-2-ol is expected to vary based on the choice of solvent, temperature, and the interactions that can occur between the compound and the solvent.

Interesting facts

Interesting Facts about 2-(2,3-dihydro-1,4-benzodioxin-3-yl)-1-(4-methoxybutylamino)propan-2-ol

The compound known as 2-(2,3-dihydro-1,4-benzodioxin-3-yl)-1-(4-methoxybutylamino)propan-2-ol is a fascinating molecule that showcases the intricate nature of organic chemistry. Here are some key points that highlight its significance and potential applications:

  • Moiety Composition: This compound contains a unique benzodioxin ring system, which is known for its diverse biological activities, including antioxidant and anti-inflammatory properties.
  • Pharmacological Interest: Compounds similar to this one have been studied as potential pharmaceuticals, particularly in the areas of neurobiology and endocrinology. They may possess abilities to interact with neurotransmitter systems.
  • Structure-Activity Relationship (SAR): The presence of different functional groups, such as the methoxybutylamino group, can significantly impact the compound’s biological activity, including potency and specificity towards targets.
  • Research Applications: Because of its structural diversity, this compound could serve as a lead compound for drug development or as a pharmacological tool in the understanding of receptor mechanisms.
  • Potential Environmentally Friendly Alternatives: The synthesis and application of compounds like this one demonstrate the growing trend in chemistry toward developing more sustainable and environmentally friendly synthetic strategies.

As the field of medicinal chemistry evolves, compounds such as 2-(2,3-dihydro-1,4-benzodioxin-3-yl)-1-(4-methoxybutylamino)propan-2-ol remind us of the intricate connection between structure and biological function. This showcases the importance of careful molecular design in creating effective therapeutic agents.

Synonyms
13627-87-7
BRN 1390008
3183 I.S.
alpha-(((4-Methoxybutyl)amino)methyl)-alpha-methyl-1,4-benzodioxan-2-methanol
1,4-BENZODIOXAN-2-METHANOL, alpha-(((4-METHOXYBUTYL)AMINO)METHYL)-alpha-METHYL-
1,4-Benzodioxin-2-methanol, 2,3-dihydro-alpha-(((4-methoxybutyl)amino)methyl)-alpha-methyl-
2-(1-Idrossi-2-metil-2-(delta-metossibutilammino))etil-1,4-benzodiossano [Italian]
2-(1-Idrossi-2-metil-2-(delta-metossibutilammino))etil-1,4-benzodiossano
2-(2,3-dihydro-1,4-benzodioxin-3-yl)-1-(4-methoxybutylamino)propan-2-ol
alpha-[[(4-Methoxybutyl)amino]methyl]-alpha-methyl-1,4-benzodioxane-2-methanol
DTXSID90929317
2-(2,3-Dihydro-1,4-benzodioxin-2-yl)-1-[(4-methoxybutyl)amino]propan-2-ol