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Tramadol Hydrochloride

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Identification
Molecular formula
C16H26ClNO2
CAS number
27203-92-5
IUPAC name
[2-(2,3-dihydro-1,4-benzodioxin-3-yl)-2-hydroxy-ethyl]-(3-methoxypropyl)ammonium;chloride
State
State
Tramadol Hydrochloride is typically in a solid state at room temperature, commonly available in a crystalline powder form. It's commonly used in pharmaceutical preparations, such as tablets or capsules.
Melting point (Celsius)
180.00
Melting point (Kelvin)
453.15
Boiling point (Celsius)
301.20
Boiling point (Kelvin)
574.35
General information
Molecular weight
299.84g/mol
Molar mass
299.8360g/mol
Density
1.2000g/cm3
Appearence

Tramadol Hydrochloride generally appears as a white or slightly off-white crystalline powder. Its fine crystalline nature and colorless to slightly white tone are typical for pharmaceutical-grade substances.

Comment on solubility

Solubility of [2-(2,3-dihydro-1,4-benzodioxin-3-yl)-2-hydroxy-ethyl]-(3-methoxypropyl)ammonium;chloride

This compound, known as [2-(2,3-dihydro-1,4-benzodioxin-3-yl)-2-hydroxy-ethyl]-(3-methoxypropyl)ammonium;chloride (C16H26ClNO2), exhibits some interesting solubility characteristics:

  • Water Solubility: The presence of the ammonium group indicates that this compound may have good solubility in water due to its ionic nature.
  • Organic Solvents: The presence of hydrophobic groups, such as the benzodioxin and methoxypropyl portions, suggests that it may also be soluble in various organic solvents.
  • Temperature Effects: Typically, solubility can increase with temperature; hence, this compound might show improved solubility at higher temperatures.
  • pH Dependence: The solubility may vary with changes in pH, as the ammonium group can change its protonation state, affecting solubility in aqueous solutions.

In summary, while specific solubility data are necessary for precise application, the interplay between its ionic characteristics and hydrophobic regions suggests that [2-(2,3-dihydro-1,4-benzodioxin-3-yl)-2-hydroxy-ethyl]-(3-methoxypropyl)ammonium;chloride has the potential for favorable solubility in both polar and non-polar solvents. As always, empirical studies are essential to confirm these theoretical predictions!

Interesting facts

Interesting Facts about [2-(2,3-dihydro-1,4-benzodioxin-3-yl)-2-hydroxy-ethyl]-(3-methoxypropyl)ammonium; chloride

This compound, a member of the ammonium salt family, features a complex structure that offers a variety of intriguing aspects for both chemists and researchers alike. Here are some noteworthy points:

  • Unique Structure: The molecule incorporates a benzodioxin moiety, which is known for its presence in various natural products and pharmaceuticals, enhancing its importance in medicinal chemistry.
  • Potential Biological Activity: Compounds with similar structural characteristics often exhibit biological activities, including antimicrobial and antitumor properties. This raises the potential for further research in drug development.
  • Ammonium Functionality: The presence of an ammonium group allows for intriguing interactions with biological systems, which could impact its solubility and biological availability.
  • Versatile Applications: Given its complex functional groups, this compound could find applications in areas from synthetic chemistry to pharmacology, making it a candidate for diverse research studies.

As we continue to explore the potential of this compound, it’s exciting to hypothesize the various applications it may hold in fields such as pharmaceutical development and synthetic organic chemistry. The intricate balance of its functional groups not only underpins its chemical behavior but also paves the way for novel discoveries.

To endorse creativity in synthetic pathways, one might reflect on how the structural arrangement of this compound could influence its reactivity. As Albert Einstein once said, "Creativity is intelligence having fun." The dual nature of chemistry as both an art and a science truly embraces this sentiment.

Synonyms
SAS 500
10402-62-7
1,4-Benzodioxan-2-methanol, alpha-(((3-methoxypropyl)amino)methyl)-, hydrochloride
1-(3-Methoxypropylamino)-2-hydroxy-2-(1,4-benzodioxan-2-yl)ethane hydrochloride