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Doxazosin

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Identification
Molecular formula
C23H25N5O5
CAS number
74191-85-8
IUPAC name
2-(2,3-dihydro-1,4-benzodioxin-5-yloxy)-N-ethyl-ethanamine
State
State

At room temperature, doxazosin is typically found in a solid state. It is commonly available in tablet form for medical use.

Melting point (Celsius)
269.00
Melting point (Kelvin)
542.15
Boiling point (Celsius)
409.20
Boiling point (Kelvin)
682.40
General information
Molecular weight
451.48g/mol
Molar mass
451.4810g/mol
Density
1.3340g/cm3
Appearence

Doxazosin typically appears as a white to off-white crystalline powder. The compound is odorless and is commonly utilized in its mesylate form for medicinal purposes.

Comment on solubility

Solubility of 2-(2,3-dihydro-1,4-benzodioxin-5-yloxy)-N-ethyl-ethanamine

The solubility of 2-(2,3-dihydro-1,4-benzodioxin-5-yloxy)-N-ethyl-ethanamine can be quite complex due to its unique chemical structure. This compound exhibits the following solubility characteristics:

  • Polar and Nonpolar Interactions: The presence of the ethyl group contributes to its nonpolar nature, while the dioxin moiety adds polar characteristics, making it soluble in a range of organic solvents.
  • Solvent Compatibility: It is generally more soluble in organic solvents such as ethanol, methanol, and dimethyl sulfoxide (DMSO) compared to water.
  • Water Solubility: Due to its molecular structure, it exhibits low solubility in water, which may limit its biological applications.
  • pH Dependence: The solubility could vary significantly with changes in pH, especially if the compound can be protonated or deprotonated in different pH environments.

In conclusion, understanding the solubility of this compound is essential for its application in various chemical processes and biological systems. To illustrate, it exemplifies the principle that like dissolves like, highlighting how its amphiphilic characteristics enable interactions with both polar and nonpolar environments.

Interesting facts

Interesting Facts about 2-(2,3-dihydro-1,4-benzodioxin-5-yloxy)-N-ethyl-ethanamine

This intriguing compound is often studied for its unique chemical structure and potential applications in various fields. Here are some noteworthy aspects:

  • Chemical Structure: The structure of 2-(2,3-dihydro-1,4-benzodioxin-5-yloxy)-N-ethyl-ethanamine features a benzodioxane core, which is well-known for its aromatic properties. The presence of both ethanamine and ethoxy groups influences the reactivity and interaction of the compound.
  • Biological Relevance: Researchers are continuously investigating the biological activity of this compound. Its structural components suggest potential interactions with various biological pathways, making it a candidate for studies in medicinal chemistry.
  • Potential Applications: The compound may have applications in the development of therapeutic agents. With ongoing research, there is a possibility of discovering new pharmaceutical benefits linked to its structural characteristics.
  • Synthetic Routes: The synthesis of this compound can involve multiple steps, often requiring careful control of reaction conditions. Understanding these synthetic pathways is essential for chemists focusing on advanced organic synthesis.
  • Related Compounds: This compound is related to a wider family of analogs, which often share similar motifs. Studying these related compounds can reveal important information about structure-activity relationships (SAR).

As a chemical scientist or student, delving into the intricate world of 2-(2,3-dihydro-1,4-benzodioxin-5-yloxy)-N-ethyl-ethanamine opens a pathway to exciting discoveries in both chemistry and biology. Its unique properties make it a captivating subject of study that promises further insights in the realm of chemical research.

Synonyms
2-[(2,3-Dihydro-1,4-benzodioxin-5-yl)oxy]-N-ethylethanamine
25475-20-1
DTXSID501187262