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Clemastine fumarate

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Identification
Molecular formula
C21H26ClNO2
CAS number
15686-51-8
IUPAC name
2-(2,3-dihydro-1,4-benzodioxin-5-yloxy)ethyl-methyl-ammonium;chloride
State
State

At room temperature, Clemastine fumarate is found in a solid state as a powder.

Melting point (Celsius)
101.00
Melting point (Kelvin)
374.15
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
459.91g/mol
Molar mass
459.9100g/mol
Density
1.4000g/cm3
Appearence

Clemastine fumarate appears as an off-white to faintly yellow crystalline powder. It is odorless and slightly bitter in taste. It is usually available in a hydrated form.

Comment on solubility

Solubility of 2-(2,3-dihydro-1,4-benzodioxin-5-yloxy)ethyl-methyl-ammonium; chloride

The solubility of 2-(2,3-dihydro-1,4-benzodioxin-5-yloxy)ethyl-methyl-ammonium; chloride can be influenced by various factors, making it a compound of interest in the field of chemical science. Generally, ammonium salts, such as this compound, exhibit good solubility in polar solvents due to their ionic nature. Here are some key considerations regarding its solubility:

  • Solvent Polarity: This compound is expected to be soluble in highly polar solvents like water, owing to the presence of the ammonium group.
  • Hydrogen Bonding: The hydrogen bonding that may occur between the solvent (such as water) and the chloride ion can enhance solubility.
  • Functional Groups: The presence of the benzodioxin moiety might impact solubility, as aromatic structures often show varied solubility characteristics depending on their configurations.
  • Temperature Effects: Solubility might increase with temperature, demonstrating a temperature-dependency characteristic typical of many ionic compounds.

Overall, while specific solubility data may vary, a focus on polarity and intermolecular interactions provides a strong basis for understanding the solubility behavior of 2-(2,3-dihydro-1,4-benzodioxin-5-yloxy)ethyl-methyl-ammonium; chloride. Further experimental investigation is essential to establish precise solubility limits in various solvents and conditions.

Interesting facts

Interesting Facts about 2-(2,3-Dihydro-1,4-benzodioxin-5-yloxy)ethyl-methyl-ammonium Chloride

This fascinating compound, with its sophisticated structure, presents a captivating case for both chemists and biochemists alike. Here are some intriguing insights that highlight its importance:

  • Pharmacological Potential: The presence of the benzodioxin moiety suggests potential applications in medicinal chemistry. Compounds of this nature are often explored for their ability to interact with biological targets, possibly contributing to the development of novel pharmaceuticals.
  • Structure-Activity Relationship: The unique arrangement of atoms within this compound opens up avenues for research into structure-activity relationships (SAR). By modifying elements of the structure, scientists can explore how changes affect biological activity and potency.
  • Mechanism of Action: With its quaternary ammonium structure, this compound could act as a surfactant or have neuromodulatory effects, making it an interesting subject for research on neurotransmitter systems.
  • Synthesis Challenges: The synthesis of this compound requires careful manipulation of its functional groups, which poses challenges in terms of selectivity and yield. It serves as an excellent topic for discussions on synthetic strategies in organic chemistry.
  • Applications in Material Science: Compounds with ionic properties, such as quaternary ammonium salts, often find uses in material science, potentially as stabilizers or in creating surface coatings.

In summary, 2-(2,3-dihydro-1,4-benzodioxin-5-yloxy)ethyl-methyl-ammonium chloride is much more than just a simple chemical formula; it carries with it the promise of innovation and discovery in various fields of science. As researchers delve into its characteristics and applications, they bring us one step closer to unlocking its full potential.

Synonyms
2906-66-3
ETHYLAMINE, 2-(1,4-BENZODIOXAN-5-YLOXY)-N-METHYL-, HYDROCHLORIDE
2-(1,4-Benzodioxan-5-yloxy)-N-methylethylamine hydrochloride