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Tamsulosin hydrochloride

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Identification
Molecular formula
C20H28N2O5S · HCl
CAS number
106463-17-6
IUPAC name
[2-(2,3-dihydro-1,4-benzodioxin-6-yl)-1-phenyl-ethyl]-dimethyl-ammonium;chloride
State
State

At room temperature, Tamsulosin hydrochloride exists as a solid.

Melting point (Celsius)
234.50
Melting point (Kelvin)
507.50
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
444.98g/mol
Molar mass
444.9810g/mol
Density
1.2300g/cm3
Appearence

Tamsulosin hydrochloride is typically a white to off-white crystalline powder. It is commonly used as a medication under various trade names.

Comment on solubility

Solubility of [2-(2,3-dihydro-1,4-benzodioxin-6-yl)-1-phenyl-ethyl]-dimethyl-ammonium;chloride

The solubility of the compound [2-(2,3-dihydro-1,4-benzodioxin-6-yl)-1-phenyl-ethyl]-dimethyl-ammonium;chloride is an interesting topic due to its unique structure and properties. Solubility can be influenced by several factors, including:

  • Polarity: The presence of quaternary ammonium groups often leads to increased solubility in polar solvents such as water.
  • Temperature: Typically, as temperature rises, solubility increases; this is relevant when considering potential applications.
  • pH Level: The pH of the solution can affect the ionization of the compound, influencing solubility.
  • Presence of Other Ions: The solubility might change in the presence of other salts or ions due to common ion effect.

It is often noted that ammonium salts, like this compound, tend to be soluble in water and exhibit good bioavailability. In a typical scenario, it could be expected to dissolve well in aqueous solutions. However, the actual solubility may require empirical testing to determine precise values under various conditions.

To summarize, while the theoretical solubility of this compound points towards good solubility in polar solvents, actual solubility can vary based on external factors, making it a subject of interest for further investigation.

Interesting facts

Interesting Facts About [2-(2,3-Dihydro-1,4-benzodioxin-6-yl)-1-phenyl-ethyl]-dimethyl-ammonium;chloride

This intriguing compound, characterized by its complex structure, serves as a prime example of the intersection between organic chemistry and pharmacology. Here are some noteworthy highlights:

  • Pharmacological Potential: The unique combination of a benzodioxin moiety with a dimethylammonium group suggests potential applications in medicinal chemistry. Compounds with similar structures often exhibit various biological activities, including anti-inflammatory and anti-cancer properties.
  • Structural Diversity: The incorporation of different functional groups, such as phenyl and dioxin rings, enhances the compound's chemical diversity and allows for the exploration of various synthetic pathways and modifications.
  • Quaternary Ammonium Compound: Being a quaternary ammonium compound, it possesses a permanently charged nitrogen atom. This attribute can significantly influence its solubility and interaction with biological membranes, making it a focus for drug development.
  • Research Interest: Chemists and drug developers are increasingly interested in such compounds for their potential therapeutic effects. Continuous research explores their role as ion channels, as well as their effectiveness in drug delivery systems.
  • Safety and Toxicology: Like many synthetic compounds, understanding the safety profile and toxicological aspects of this compound is crucial. Studies evaluating its chronic effects and bioaccumulation contribute to its risk assessment for pharmaceutical use.

In summary, the compound [2-(2,3-dihydro-1,4-benzodioxin-6-yl)-1-phenyl-ethyl]-dimethyl-ammonium;chloride is not just a mere chemical formula but a potential key player in the study of new therapeutic agents. Its unique structural features open doors for further exploration, making it a fascinating subject of study in modern chemistry.

Synonyms
N,N-Dimethyl-alpha-phenyl-1,4-benzodioxan-6-ethylamine hydrochloride
15057-50-8
1,4-BENZODIOXAN-6-ETHYLAMINE, N,N-DIMETHYL-alpha-PHENYL-, HYDROCHLORIDE