MDA (3,4-Methylenedioxyamphetamine)

Identification

Molecular formula

C₁₀H₁₃NO₂

CAS number

4764-17-4

IUPAC name

2-(2,3-dihydro-1,4-benzodioxin-6-yloxy)-N-methyl-ethanamine

State

Solid at room temperature. MDA is commonly encountered as a powder or tablet in illicit settings.

Melting point (Celsius)

182.00

Melting point (Kelvin)

455.15

Boiling point (Celsius)

100.00

Boiling point (Kelvin)

373.15

General information

Molecular weight

179.22g/mol

Molar mass

179.2150g/mol

Density

1.1820g/cm³

Appearence

MDA typically appears as a white to off-white crystalline powder. It can also be found in tablet form when pressed for drug use.

Comment on solubility

Solubility of 2-(2,3-dihydro-1,4-benzodioxin-6-yloxy)-N-methyl-ethanamine

This compound, known for its intriguing structure, exhibits varied solubility characteristics that are dependent on several factors. Generally, the solubility of substances can be influenced by:

Polarity: The presence of polar functional groups can enhance the solubility of the compound in polar solvents like water.
Structural Features: The benzodioxin moiety may affect the overall solubility due to its rigid aromatic structure, potentially leading to lower solubility in non-polar environments.
Temperature: As with many organic compounds, increased temperature often leads to increased solubility.
pH levels: The solubility can be significantly affected by the pH of the surrounding medium if the compound can ionize.

Many compounds in the same structural family have been reported to be poorly soluble in water but can be more soluble in organic solvents. In conclusion, the solubility of 2-(2,3-dihydro-1,4-benzodioxin-6-yloxy)-N-methyl-ethanamine is likely to reflect a *moderate* solubility profile where experimental assessment is crucial for definitive understanding. As the saying goes, “like dissolves like” — thus, knowledge of its polar and non-polar regions will guide practical application in solubility determinations.

Interesting facts

Interesting Facts about 2-(2,3-Dihydro-1,4-benzodioxin-6-yloxy)-N-methyl-ethanamine

This compound presents a captivating case study in organic chemistry due to its intriguing structure and potential applications. The presence of both a benzodioxin ring and an N-methyl-ethanamine group highlights the compound's structural complexity, making it a subject of interest in the study of pharmaceuticals and organic synthesis.

Key Highlights:

Pharmacological Interest: Compounds featuring the benzodioxin structure are often explored for their pharmacological properties, with many derivatives showing potential as therapeutic agents.
Synergistic Effects: The combination of the benzodioxin moiety and the amine may lead to synergistic effects, enhancing biological activity or selectivity in various applications.
Organic Synthesis: The synthesis of such complex molecules can serve as an excellent teaching example for organic chemistry students, showcasing techniques such as ring closures and functional group transformations.
Investigative Applications: Researchers are investigating similar compounds in the context of neuropharmacology, especially regarding their effects on receptor modulation.

Furthermore, it is essential to appreciate how adjusting the substituents in similar compounds can dramatically influence their chemical properties and biological activity. As with many derivatives in organic chemistry, the study of 2-(2,3-dihydro-1,4-benzodioxin-6-yloxy)-N-methyl-ethanamine could lead to an understanding of structure-activity relationships (SARs) that is vital for drug design.

In summary, the exploration of such compounds is not just about understanding individual components but involves a broader perspective encompassing medicinal chemistry, synthetic strategies, and the intricate dance of molecular interactions in biological systems.