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Methylprednisolone hemihydrate

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Identification
Molecular formula
C11H22N2O10S2
CAS number
83-43-2
IUPAC name
2-[[2,3-dihydroxy-4-(2-methylsulfonyloxyethylamino)butyl]amino]ethyl methanesulfonate
State
State

The compound is typically found in a solid state at room temperature and is extensively used in pharmaceutical formulations as it has excellent stability and solubility.

Melting point (Celsius)
147.00
Melting point (Kelvin)
420.15
Boiling point (Celsius)
200.00
Boiling point (Kelvin)
473.15
General information
Molecular weight
314.36g/mol
Molar mass
314.3600g/mol
Density
1.3500g/cm3
Appearence

This compound typically appears as a white to slightly off-white crystalline powder. It is odorless and stable under normal conditions of use and storage.

Comment on solubility

Solubility of 2-[[2,3-dihydroxy-4-(2-methylsulfonyloxyethylamino)butyl]amino]ethyl methanesulfonate

The solubility of 2-[[2,3-dihydroxy-4-(2-methylsulfonyloxyethylamino)butyl]amino]ethyl methanesulfonate in various solvents can be quite fascinating due to its unique chemical structure. As a sulfonate ester derivative, this compound exhibits particular solubility properties based on its functional groups.

Key points regarding solubility:

  • Polar solvent compatibility: Given the presence of hydroxyl and sulfonate groups, we can expect enhanced solubility in polar solvents such as water and alcohols.
  • Hydrophilicity: The hydroxyl groups contribute to a significant degree of hydrophilicity, likely increasing solubility in aqueous solutions.
  • Temperature influence: Solubility may increase with temperature, which is common for many ionic and polar compounds.
  • pH dependence: The solubility could also vary with pH, particularly due to protonation or deprotonation of functional groups under different acidic or basic conditions.

In summary, while general trends suggest that this compound is likely soluble in aqueous media due to its polar characteristics, precise solubility data, such as solubility limits and behavior in non-polar solvents, would be critical for a more thorough understanding. As always, experimental validation will be essential in confirming these theoretical solubility assertions.

Interesting facts

Interesting Facts About 2-[[2,3-Dihydroxy-4-(2-methylsulfonyloxyethylamino)butyl]amino]ethyl Methanesulfonate

2-[[2,3-Dihydroxy-4-(2-methylsulfonyloxyethylamino)butyl]amino]ethyl methanesulfonate is a fascinating compound with diverse applications and unique chemistry. Here are some intriguing points that highlight its significance:

  • Pharmaceutical Relevance: This compound is a key player in medicinal chemistry, particularly in the design of therapeutic agents targeting various diseases. Its structure suggests potential functionalities in drug delivery mechanisms.
  • Functional Groups: The presence of hydroxyl groups and sulfonate features indicates that this compound may exhibit interesting properties such as enhanced solubility and biological activity, which are critical for pharmacological applications.
  • Structure-Activity Relationship (SAR): The intricate molecular architecture allows researchers to explore how minor modifications can significantly influence its activity, paving the way for optimized drug design.
  • Potential Enzyme Inhibitor: Due to its specific structural motifs, there is a potential for this compound to act as an inhibitor of certain enzymes, contributing to therapeutic strategies against particular metabolic disorders.
  • Research and Development: Ongoing studies focus on synthesizing related derivatives, exploring their biological evaluations, and discovering novel applications within the fields of biotechnology and pharmacology.

In summary, 2-[[2,3-Dihydroxy-4-(2-methylsulfonyloxyethylamino)butyl]amino]ethyl methanesulfonate is not only an interesting compound but also a potent candidate for future research and development in the realm of medicinal chemistry. As the field progresses, understanding the potential of such compounds encourages the advancement of innovative therapeutic solutions.

Synonyms
2-[[2,3-dihydroxy-4-(2-methylsulfonyloxyethylamino)butyl]amino]ethyl methanesulfonate
NSC122402
DTXSID90863328
1, 4-Di(mesyloxyethylamino)erythritol
NS00120587
1, 4-Bis(2'-mesyloxyethylamino)-1,4-dideoxymesoerythritol
[(2,3-Dihydroxybutane-1,4-diyl)bis(azanediyl)ethane-2,1-diyl] dimethanesulfonate
1,4-Dideoxy-1, {4-bis[(2-hydroxyethyl)amino]erythritol} 1,4-dimethanesulfonate (ester)
5,6-Dihydroxy-12,12-dioxido-11-oxa-12-thia-3,8-diazatridec-1-yl methanesulfonate
3,14-Dioxa-2,15-dithia-6,11-diazahexadecane-8,9-diol, 2, 2,15,15-tetraoxide, (R*,S*)-
Erythritol, {1,4-dideoxy-1,4-bis[(2-hydroxyethyl)amino]-,} 1, 4-dimethanesulfonate (ester), meso-