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Galantamine hydrobromide

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Identification
Molecular formula
C17H21NO3
CAS number
69353-21-5
IUPAC name
2-(2,3-dimethoxyphenyl)ethyl-bis[2-(propylcarbamoyloxy)ethyl]ammonium;4-hydroxy-4-oxo-but-2-enoate
State
State

At room temperature, Galantamine hydrobromide exists in a solid state. Given its pharmaceutical applications, it is often formulated into tablets or capsules for oral administration. The solid form ensures stability and ease of storage.

Melting point (Celsius)
125.00
Melting point (Kelvin)
398.15
Boiling point (Celsius)
410.00
Boiling point (Kelvin)
683.15
General information
Molecular weight
456.51g/mol
Molar mass
456.5100g/mol
Density
1.2100g/cm3
Appearence

Galantamine hydrobromide typically appears as a white to almost white powder. The compound is hygroscopic, meaning it can easily absorb moisture from the environment. It is soluble in water and methanol, allowing it to be used effectively in various pharmaceutical formulations.

Comment on solubility

Solubility Properties

The compound 2-(2,3-dimethoxyphenyl)ethyl-bis[2-(propylcarbamoyloxy)ethyl]ammonium;4-hydroxy-4-oxo-but-2-enoate exhibits intricate solubility characteristics due to its complex structure. Solubility can be influenced by several factors, including the following:

  • Polarity: The presence of multiple polar functional groups suggests that this compound may be soluble in polar solvents such as water or methanol.
  • Hydrogen Bonding: Functional groups capable of hydrogen bonding can enhance solubility, particularly in aqueous environments.
  • Alkyl Chains: The propyl groups may exhibit hydrophobic characteristics, potentially reducing solubility in highly polar solvents and promoting solubility in organic solvents.

Considering these aspects, the solubility of this compound might be classified as:

  1. Moderately Soluble: Likely to dissolve in both polar and non-polar solvents but may show varied levels depending on solvent conditions.
  2. pH Dependence: The presence of acidic and basic functional groups suggests that solubility could change with pH, impacting the ionization state of the molecule.

"The solubility of compounds is often a reflection of their molecular interactions and is essential for understanding their behavior in different environments."

Overall, understanding the solubility of this compound is crucial for its practical applications and for predicting its behavior in biological systems and chemical reactions.

Interesting facts

Interesting Facts about 2-(2,3-Dimethoxyphenyl)ethyl-bis[2-(propylcarbamoyloxy)ethyl]ammonium; 4-Hydroxy-4-oxo-but-2-enoate

The compound 2-(2,3-dimethoxyphenyl)ethyl-bis[2-(propylcarbamoyloxy)ethyl]ammonium; 4-hydroxy-4-oxo-but-2-enoate is a complex organic molecule that showcases the intriguing intersection of organic chemistry and pharmacology. Below are some compelling aspects of this compound:

  • Unique Structure: The structure features a bis(ammonium) moiety combined with distinct aromatic and aliphatic groups, making it a promising candidate for various bioactive applications. Its multi-functional nature provides insights into how different chemical groups can interact within biological systems.
  • Potential Applications: Research suggests that derivatives of this compound may exhibit significant pharmacological properties, including antitumor and anti-inflammatory activities.
  • Mechanism of Action: It is believed that the compound may act through modulation of certain physiological pathways, which could lead to innovative therapeutic strategies in medicine.
  • Research Interest: The intricate balance between the hydrophilic and hydrophobic regions in the compound enhances its permeability through biological membranes, making it a subject of interest in drug delivery systems.

As we explore this compound further, it is essential to consider not only its chemical properties but also how structural variations can lead to different biological effects. “The beauty of chemistry lies in its ability to create diversity from simplicity,” a notion that perfectly encapsulates the potential of such compounds in medicinal chemistry.

Future research could investigate the synthesis of analogs and their biological activities, highlighting the ongoing evolution of this exciting branch of science.