Skip to main content

Mefenamic acid

ADVERTISEMENT
Identification
Molecular formula
C15H15NO2
CAS number
61-68-7
IUPAC name
2-(2,3-dimethylanilino)benzoic acid
State
State

Mefenamic acid is typically solid at room temperature. The compound exists as fine crystalline powder, which may show slight variations in appearance depending on the specific conditions like humidity or handling.

Melting point (Celsius)
230.00
Melting point (Kelvin)
503.20
Boiling point (Celsius)
376.40
Boiling point (Kelvin)
649.50
General information
Molecular weight
241.28g/mol
Molar mass
241.2820g/mol
Density
1.2000g/cm3
Appearence

Mefenamic acid appears as a white crystalline powder. It may sometimes appear slightly off-white, but generally retains the crystalline structure typical of many organic compounds. It is odorless or may have a slight characteristic odor in its pure form.

Comment on solubility

Solubility of 2-(2,3-dimethylanilino)benzoic acid (C15H15NO2)

2-(2,3-dimethylanilino)benzoic acid, a carboxylic acid derivative, exhibits interesting solubility characteristics that are influenced by both its molecular structure and the presence of functional groups. The solubility of this compound in various solvents can be generally summarized as follows:

  • Water: This compound has limited solubility in water due to its hydrophobic aromatic structure, which restricts its interaction with polar water molecules.
  • Organic Solvents: It is more soluble in organic solvents such as ethanol and methanol, where the nonpolar regions of the molecule can better interact with the solvent.
  • pH Dependence: The solubility may vary with pH; at lower pH values, the carboxylic acid group can be protonated, which might enhance solubility in polar environments compared to its neutral form.

Quote: "The solubility of a compound is often a key consideration in its practical applications, influencing factors such as bioavailability and reactivity."

In summary, 2-(2,3-dimethylanilino)benzoic acid's solubility is dictated by its *aromatic* characteristics and the functional groups within its structure, leading to diverse interactions in different solvents.

Interesting facts

Interesting Facts about 2-(2,3-Dimethylanilino)benzoic Acid

2-(2,3-Dimethylanilino)benzoic acid, commonly referred to as a derivative of benzoic acid, is an intriguing compound that has garnered attention in various fields of research and applications. Here are some fascinating aspects:

  • Structure and Functionality: This compound features a benzoic acid core with a dimethylaniline substituent, which significantly influences its chemical behavior and reactivity. The presence of the amine group contributes to its ability to participate in various chemical reactions, making it a useful building block in organic synthesis.
  • Potential Applications: The compound is of interest in the pharmaceutical industry as it may serve as a precursor or intermediate in the synthesis of therapeutic agents. Its unique structure could promote exploration in drug development, particularly in creating new analgesics or anti-inflammatory medicines.
  • Pigmentation and Dyes: Due to its aromatic nature, 2-(2,3-dimethylanilino)benzoic acid might also find applications in the dye industry. Compounds with similar structures are commonly used as coloring agents, providing a vibrant palette for textiles and plastics.
  • Research Significance: This compound serves as a point of interest for many chemistry students and professionals due to its synthetic pathways and functional properties. It exemplifies how substituents on a base structure can lead to diverse applications and properties.

As we study compounds like 2-(2,3-dimethylanilino)benzoic acid, we uncover not only the beauty of their chemical structures but also the vast potential they hold in various scientific advancements. Each discovery in this area contributes to the ever-evolving tapestry of chemical knowledge.

Synonyms
mefenamic acid
61-68-7
Ponstel
2-[(2,3-dimethylphenyl)amino]benzoic acid
Mephenamic acid
Mephenaminic acid
2-((2,3-Dimethylphenyl)amino)benzoic acid
Ponstan
Methenamic acid
Parkemed
Vialidon
Bonabol
Coslan
Lysalgo
Mefacit
Ponalar
Tanston
Bafameritin-M
Tamany Bonsan
Acide mefenamique
Mefenaminsaeure
Mefenamate
Namphen
Ponstan forte
Bafhameritin-M
Ponstil
Ponstyl
Pontal
Mefanamic acid
N-2,3-Xylylanthranilic acid
Acido mefenamico
CN-35355
Mefenaminic Acid
Mefedolo
Mefenacid
Mycasaal
HL 1
Rolan
INF-3355
Acidum mefenamicum
INF 3355
N-(2,3-Xylyl)anthranilic acid
CI-473
2-(2,3-Dimethylanilino)benzoic acid
N-(2,3-Xylyl)-2-aminobenzoic acid
AGN-1255
N-(2,3-Dimethylphenyl)anthranilic acid
Ac. mefenamico
CL 473
Gardan
Anthranilic acid, N-2,3-xylyl-
2-(2,3-dimethylphenylamino)benzoic acid
CN 35355
MFCD00051721
NSC 94437
Acide mefenamique [INN-French]
Acido mefenamico [INN-Spanish]
Acidum mefenamicum [INN-Latin]
Benzoic acid, 2-[(2,3-dimethylphenyl)amino]-
HSDB 3115
EINECS 200-513-1
NSC-94437
Benzoic acid, 2-((2,3-dimethylphenyl)amino)-
2-Diphenylaminecarboxylic acid, 2',3'-dimethyl-
BRN 2216243
CHEBI:6717
DTXSID5023243
UNII-367589PJ2C
M01AG01
Benzoic acid, 2-(2,3-dimethylphenyl)amino-
NSC94437
Anthranilic acid, N-(2,3-xylyl)-
CI 473
CHEMBL686
367589PJ2C
J2.344B
MLS000069709
DTXCID103243
CAS-61-68-7
2-(2,3-dimethylphenyl)aminobenzoic acid
NCGC00016278-07
SMR000058188
Mefenamic acid [USAN:USP:INN:BAN:JAN]
Mefenaminsaeure [German]
Ac. mefenamico [Italian]
in-M
Acide mefenamique [French]
MEFENAMIC ACID (MART.)
MEFENAMIC ACID [MART.]
Acide mefenamique (INN-French)
Acido mefenamico (INN-Spanish)
Acidum mefenamicum (INN-Latin)
MEFENAMIC ACID (USP-RS)
MEFENAMIC ACID [USP-RS]
MEFENAMIC ACID (EP MONOGRAPH)
MEFENAMIC ACID [EP MONOGRAPH]
MEFENAMIC ACID (USP MONOGRAPH)
MEFENAMIC ACID [USP MONOGRAPH]
Mefenamic acid (USAN:USP:INN:BAN:JAN)
2-(2,3-Xylidino)benzoic Acid
SR-01000000216
Mefenaminsaure
mefenamic-acid
Prestwick_506
Mefenamic Acid,(S)
Spectrum_000174
CPD000058188
Opera_ID_542
Prestwick0_000054
Prestwick1_000054
Prestwick2_000054
Prestwick3_000054
Spectrum2_001941
Spectrum3_001082
Spectrum4_001235
Spectrum5_001341
M1782
Mefenamic acid (Standard)
Anthranilic acid,3-xylyl-
cid_4044
SCHEMBL3544
MEFENAMIC ACID [MI]
Oprea1_193889
BSPBio_000207
BSPBio_002724
KBioGR_001730
KBioSS_000654
MEFENAMIC ACID [INN]
MEFENAMIC ACID [JAN]
MLS001074162
DivK1c_000298
MEFENAMIC ACID [HSDB]
MEFENAMIC ACID [USAN]
SPECTRUM1501103
SPBio_002001
SPBio_002128
MEFENAMIC ACID [VANDF]
BPBio1_000229
F0850-6853
GTPL2593
SGCUT00005
WLN: QVR BMR B1 C1
MEFENAMIC ACID [WHO-DD]
HMS500O20
HY-B0574R
KBio1_000298
KBio2_000654
KBio2_003222
KBio2_005790
KBio3_001944
BRD8217
NINDS_000298
HMS1568K09
HMS1921D13
HMS2090B07
HMS2092B17
HMS2095K09
HMS2232P18
HMS3259M19
HMS3370K18
HMS3652A10
HMS3712K09
HMS3885O22
Pharmakon1600-01501103
Mefenamic acid (JP18/USP/INN)
Mefenamic acid, analytical standard
ALBB-025759
BCP08499
BRD-8217
HY-B0574
to_000071
Tox21_110344
Tox21_301983
BBL003564
BDBM50134036
CCG-39434
MEFENAMIC ACID [ORANGE BOOK]
NSC757834
s4078
STK666691
AKOS001025551
AKOS002388313
Benzoic acid,3-dimethylphenyl)amino]-
Tox21_110344_1
DB00784
FM25038
NC00517
NSC-757834
IDI1_000298
SMP2_000141
2-(2,3-Dimethylanilino)benzoic acid #
NCGC00016278-01
NCGC00016278-02
NCGC00016278-03
NCGC00016278-04
NCGC00016278-05
NCGC00016278-06
NCGC00016278-10
NCGC00022393-03
NCGC00022393-04
NCGC00022393-05
NCGC00255401-01
AC-11160
AS-12677
SY045797
SBI-0051636.P002
2-(2,3-Dimethyl-phenylamino)-benzoic acid
2-[(2,3-dimethylphenyl) amino]benzoic acid
2-Diphenylaminecarboxylic acid,3'-dimethyl-
AB00052200
NS00000218
SW196700-3
UNM000001233403
EN300-16695
C02168
D00151
AB00052200-17
AB00052200_18
AB00052200_19
Q284321
SR-01000000216-2
SR-01000000216-4
BRD-K92778217-001-06-1
BRD-K92778217-001-31-9
BRD-K92778217-001-32-7
Z56755828
BENZOIC ACID, 2-((2,3-DIMETHYL(PHENYL)AMINO)-
2-(2,3-Dimethyl-phenylamino)-benzoic acid(Mefenamic acid)
2-[(2,3-Dimethylphenyl)amino]-benzoic acid;Mefacit;Mefenacid
Mefenamic acid, European Pharmacopoeia (EP) Reference Standard
Mefenamic acid, United States Pharmacopeia (USP) Reference Standard
200-513-1
InChI=1/C15H15NO2/c1-10-6-5-9-13(11(10)2)16-14-8-4-3-7-12(14)15(17)18/h3-9,16H,1-2H3,(H,17,18