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Diclofenac

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Identification
Molecular formula
C8H9Cl2N3
CAS number
25282-13-5
IUPAC name
2-[(2,4-dichlorophenyl)methyl]guanidine
State
State

The compound is typically a solid at room temperature, appearing as a crystalline substance.

Melting point (Celsius)
105.00
Melting point (Kelvin)
378.15
Boiling point (Celsius)
359.00
Boiling point (Kelvin)
632.15
General information
Molecular weight
203.09g/mol
Molar mass
203.0860g/mol
Density
1.3450g/cm3
Appearence

2-[(2,4-dichlorophenyl)methyl]guanidine typically appears as a white to off-white crystalline solid.

Comment on solubility

Solubility of 2-[(2,4-dichlorophenyl)methyl]guanidine

The solubility of 2-[(2,4-dichlorophenyl)methyl]guanidine can be quite intriguing due to its unique molecular structure and the presence of various functional groups. Understanding its solubility is crucial for predicting its behavior in different environments. Here are some key points to consider:

  • Polarity: The compound exhibits a moderate level of polarity due to the guanidine group, which can influence its solubility in polar solvents.
  • Solvent Interaction: It is more soluble in aqueous solutions and polar organic solvents compared to non-polar solvents, showcasing a tendency to interact favorably with water molecules.
  • Hydrogen Bonding: The presence of NH groups allows for potential hydrogen bonding with water, enhancing solubility further.
  • Practical Considerations: When considering the solubility of this compound, it is essential to take into account factors such as temperature and pH levels, which can significantly impact solubility rates.

In summary, while 2-[(2,4-dichlorophenyl)methyl]guanidine is generally soluble in water and polar solvents, its solubility characteristics can be vastly influenced by external conditions, making it an interesting compound to study.

Interesting facts

Interesting Facts About 2-[(2,4-Dichlorophenyl)methyl]guanidine

2-[(2,4-Dichlorophenyl)methyl]guanidine is a fascinating compound that straddles multiple fields of chemistry, from organic synthesis to pharmaceutical applications. Here are some intriguing insights:

  • Applications in Medicine: This compound is recognized for its potential use in various therapeutic areas. Its structure allows it to interact with specific biological targets, making it a candidate for research in conditions such as hypertension and certain types of cancer.
  • Structure-Activity Relationship: The unique arrangement of the dichlorophenyl group contributes to the compound's biological activity. Studying its structure helps chemists understand how small changes in molecular configuration can significantly affect pharmacological properties.
  • Mechanism of Action: Research indicates that 2-[(2,4-Dichlorophenyl)methyl]guanidine may influence the regulation of neurotransmitters, which is critical in developing new medications for neurological disorders. Understanding its mechanism helps in creating more effective and targeted treatments.
  • Synthesis Challenges: The synthesis of this compound can present challenges, primarily due to the need for precise control over reaction conditions. This makes it an interesting subject for organic chemists looking to hone their skills in reaction optimization and yield enhancement.
  • Environmental Considerations: While researching this compound, scientists are also mindful of its environmental impact. The use of chlorinated compounds raises concerns, and researchers are constantly investigating ways to minimize any ecological footprints in its production and application.

In summary, 2-[(2,4-Dichlorophenyl)methyl]guanidine stands out not just for its potential utility in medicine but also for the scientific inquiries it inspires regarding molecular design, synthesis challenges, and environmental sustainability. As scientists continue to explore its properties, we gain better insights into the complexities of chemical interactions and therapeutic advancements.

Synonyms
(2,4-Dichlorobenzyl)guanidine
3911-40-8
GUANIDINE, (2,4-DICHLOROBENZYL)-
BRN 2373964
Guanidine, ((2,4-dichlorophenyl)methyl)-
DTXSID00192358
DTXCID10114849
1-(2,4-Dichlorobenzyl)guanidine
SCHEMBL972321
SY340570