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Iopanoic acid

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Identification
Molecular formula
C11H12I3NO3
CAS number
96-83-3
IUPAC name
2-[[2,4,6-triiodo-3-(2-oxopyrrolidin-1-yl)phenyl]methyl]butanoic acid
State
State

At room temperature, iopanoic acid is in a solid state. Its stability in this form makes it useful for handling and storage in a variety of pharmaceutical and chemical procedures.

Melting point (Celsius)
235.00
Melting point (Kelvin)
508.15
Boiling point (Celsius)
573.00
Boiling point (Kelvin)
846.15
General information
Molecular weight
663.87g/mol
Molar mass
663.8730g/mol
Density
2.6240g/cm3
Appearence

Iopanoic acid is a white to off-white crystalline powder. It doesn't have a distinct odor and is used in the form of tablets or as a powder for various medical applications, with solubility properties that cater to its usage in contrast media.

Comment on solubility

Solubility of 2-[[2,4,6-triiodo-3-(2-oxopyrrolidin-1-yl)phenyl]methyl]butanoic acid

The solubility of 2-[[2,4,6-triiodo-3-(2-oxopyrrolidin-1-yl)phenyl]methyl]butanoic acid can be quite complex due to its multifaceted structure. Here are some key points to consider:

  • Polarity: The presence of the carboxylic acid group significantly influences solubility. This group can engage in hydrogen bonding with water, potentially increasing aqueous solubility.
  • Iodine Atoms: The tri-iodinated phenyl moiety can affect hydrophilicity, often leading to lower solubility in organic solvents due to the bulky and non-polar nature of iodine.
  • Solvent Compatibility: Depending on the solvent, this compound might exhibit varied solubility patterns. Typical organic solvents like ethanol or dimethyl sulfoxide (DMSO) could provide better solubility than water.
  • Temperature Influence: Solubility can also be temperature-dependent; higher temperatures may enhance solute-solvent interactions leading to increased solubility.

In conclusion, it is crucial to explore various conditions and solvents when determining the solubility characteristics of this compound. As with many chemical compounds, understanding solubility allows for better application in chemical processes and formulations.

Interesting facts

Interesting Facts About 2-[[2,4,6-Triiodo-3-(2-oxopyrrolidin-1-yl)phenyl]methyl]butanoic acid

2-[[2,4,6-triiodo-3-(2-oxopyrrolidin-1-yl)phenyl]methyl]butanoic acid represents a fascinating class of compounds that merge organic chemistry with medicinal potential. This unique compound features:

  • Triiodination: The presence of three iodine atoms introduces interesting properties, enhancing the compound's ability to engage in various biochemical processes.
  • Oxopyrrolidine functionality: This component of the molecule can contribute significantly to its biological activity, as it may resemble naturally occurring neurotransmitters and interact with biological targets.
  • Potential Therapeutic Uses: Compounds with such complex structures are often investigated for their roles in treatments for various conditions, including inflammation and neurological disorders.
  • Reactivity: The combination of polar and non-polar regions within the molecule suggests potential for diverse reactivity, highlightening the importance of understanding such compounds in medicinal chemistry.

Key Aspects of Study

As science continually explores the potential of synthetic compounds, 2-[[2,4,6-triiodo-3-(2-oxopyrrolidin-1-yl)phenyl]methyl]butanoic acid acts as a reminder of:

  1. How modifications in molecular architecture can lead to entirely new functionalities.
  2. The importance of interdisciplinary approaches combining chemistry, biology, and pharmacology for drug discovery.
  3. The evolving understanding of iodine's role in pharmaceutical compounds, both in terms of enhancing solubility and bioactivity.

In conclusion, this compound not only presents a complex molecular architecture but also a plethora of opportunities for research and discovery that can enhance our understanding of therapeutic agents. As chemists and students delve deeper, they often find that such compounds lead to exciting avenues in both academic and clinical settings.

Synonyms
Iolidonic acid
Acido iolidonico
21766-53-0
Acide iolidonique
B1H5V6OZSE
Acidum iolidonicum
2'-Ethyl-3-(N-(2-oxopyrrolidinyl))-2,4,6-triiodo-3'-phenylpropionic acid
RefChem:148586
2-[[2,4,6-triiodo-3-(2-oxopyrrolidin-1-yl)phenyl]methyl]butanoic acid
Iolidonic acid [INN]
2-{[2,4,6-triiodo-3-(2-oxopyrrolidin-1-yl)phenyl]methyl}butanoic acid
UNII-B1H5V6OZSE
Acide iolidonique [French]
SCHEMBL2110121
Acide iolidonique [INN-French]
Acido iolidonico [INN-Spanish]
Acidum iolidonicum [INN-Latin]
CHEMBL2105003
Acido iolidonico [Latin,Spanish]
DTXSID80865013
B8560
NS00123465
Q27274252
alpha-Ethyl-2,4,6-triiodo-3-(2-oxo-1-pyrrolidinyl)hydrocinnamic acid
.ALPHA.-ETHYL-2,4,6-TRIIODO-3-(2-OXO-1-PYRROLIDINYL)HYDROCINNAMIC ACID