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Iotroxic acid

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Identification
Molecular formula
C15H18I3NO4
CAS number
42439-82-1
IUPAC name
2-[2,4,6-triiodo-3-[methyl(propanoyl)amino]phenoxy]hexanoic acid
State
State

At room temperature, iotroxic acid is typically a solid. It is not very soluble in water, due primarily to its large, bulky structure, but it can dissolve in certain organic solvents. The presence of multiple iodine atoms also means it has a relatively high molecular weight for an organic compound of its size.

Melting point (Celsius)
190.00
Melting point (Kelvin)
463.00
Boiling point (Celsius)
260.00
Boiling point (Kelvin)
533.00
General information
Molecular weight
821.95g/mol
Molar mass
821.9470g/mol
Density
2.2600g/cm3
Appearence

Iotroxic acid appears as a white to off-white crystalline powder. It is quite dense due to the presence of three iodine atoms, which contribute significantly to its mass and volume. The compound may also form as a solid with a slightly yellowish tinge, depending on its purity and the presence of any impurities.

Comment on solubility

Solubility of 2-[2,4,6-triiodo-3-[methyl(propanoyl)amino]phenoxy]hexanoic acid

The solubility of 2-[2,4,6-triiodo-3-[methyl(propanoyl)amino]phenoxy]hexanoic acid is influenced by several factors:

  • Polarity: The presence of multiple iodine atoms and polar functional groups in the structure increases the overall polarity of the compound. This generally results in higher solubility in polar solvents.
  • Hydrogen Bonding: The carboxylic acid group may engage in hydrogen bonding with water, enhancing solubility. In contrast, the overall complexity and bulkiness of the compound can hinder its solubility.
  • Chain Length: The hexanoic acid moiety provides a hydrophobic hydrocarbon chain which may reduce solubility in aqueous environments.

In summary, while the polar functional groups suggest some degree of solubility in polar solvents like water, the hydrophobic character introduced by the hexanoic part may lead to limited solubility. Therefore, it is essential to consider both the hydrophilic and hydrophobic characteristics when predicting the solubility behavior of this compound in various solvents.

Interesting facts

Interesting Facts about 2-[2,4,6-triiodo-3-[methyl(propanoyl)amino]phenoxy]hexanoic acid

This fascinating compound is notable for its unique structural elements that contribute to its application in various fields, particularly in medicinal chemistry and radiology. Here are some key points:

  • Triiodo Substitution: The presence of three iodine atoms significantly enhances the compound's radiological properties. Iodine is known for its ability to absorb X-rays, making this compound potentially useful in diagnostic imaging.
  • Amino Acid Derivative: Featuring an amino acid-like structure, this compound showcases typical characteristics of biocompatible molecules, which are valuable in the field of drug development.
  • Phenoxy Group: The phenoxy functional group contributes to the compound's hydrophilic nature, impacting its behavior in biological systems and its interaction with membranes.
  • Hexanoic Acid Moiety: The hexanoic acid chain adds to the overall lipophilicity of the compound, facilitating its ability to interact with lipid membranes—important in pharmacokinetics.

This compound exemplifies the intricate relationship between structure and function in chemistry, demonstrating how modifications at the molecular level can lead to compounds with significant potential for medical applications. As we delve deeper into the study of such compounds, the exploration of their properties and potential uses continues to inspire new innovations in the field.

As the chemist Linus Pauling once said, "The best way to have a good idea is to have a lot of ideas." The study of chemical compounds like 2-[2,4,6-triiodo-3-[methyl(propanoyl)amino]phenoxy]hexanoic acid reminds us of the importance of creativity and exploration in scientific inquiry.

Synonyms
BRN 2677350
2-(3-(N-Methylpropionamido)-2,4,6-triiodophenoxy)hexanoic acid
24340-27-0
HEXANOIC ACID, 2-(3-(N-METHYLPROPIONAMIDO)-2,4,6-TRIIODOPHENOXY)-
RefChem:347664
DTXSID60947184
2-{2,4,6-Triiodo-3-[methyl(propanoyl)amino]phenoxy}hexanoic acid