Skip to main content

Mitomycin C

ADVERTISEMENT
Identification
Molecular formula
C15H18N4O5
CAS number
50-07-7
IUPAC name
[2-[2,5-bis(aziridin-1-yl)-4-methyl-3,6-dioxo-cyclohexa-1,4-dien-1-yl]-2-methoxy-ethyl] carbamate
State
State

At room temperature, Mitomycin C is typically in a solid state as a crystalline powder. It is stable under normal conditions but must be stored carefully to prevent degradation.

Melting point (Celsius)
360.00
Melting point (Kelvin)
633.15
Boiling point (Celsius)
276.10
Boiling point (Kelvin)
549.30
General information
Molecular weight
334.34g/mol
Molar mass
334.3250g/mol
Density
1.3000g/cm3
Appearence

Mitomycin C typically appears as a blue-violet crystalline powder. It can also be described as a light-purple crystalline solid depending on the form it's in.

Comment on solubility

Solubility Overview

The compound 2-[2,5-bis(aziridin-1-yl)-4-methyl-3,6-dioxo-cyclohexa-1,4-dien-1-yl]-2-methoxy-ethyl carbamate, with the chemical formula C15H18N4O5, exhibits specific solubility characteristics that are crucial for its applications.

Solubility Characteristics

  • Polarity: The presence of both amino and hydroxyl functional groups suggests that this compound may demonstrate moderate to high polarity.
  • Solvent Compatibility: Due to its polar nature, it is likely that the compound is more soluble in polar solvents such as water and alcohols, rather than in non-polar solvents.
  • pH Dependence: The solubility may also be affected by pH, indicating that the compound could hydrolyze or react in extreme pH conditions.
  • Temperature Effects: Increasing temperature might enhance solubility; however, empirical tests would confirm this behavior.

Practical Implications

Understanding the solubility profile of this compound is essential for its use in various applications, particularly in medicinal chemistry where bioavailability and interaction with biological systems rely heavily on solubility. As with many chemical compounds, it is important to conduct thorough solubility testing for practical applications and formulations.

Interesting facts

Interesting Facts About 2-[2,5-bis(aziridin-1-yl)-4-methyl-3,6-dioxo-cyclohexa-1,4-dien-1-yl]-2-methoxy-ethyl carbamate

This unique compound, known for its potential applications in medicinal chemistry, presents an intriguing structure with multifaceted functionalities. Here are some engaging highlights:

  • Versatile Reactivity: The presence of aziridine rings in the structure imparts this compound with the capability to participate in a variety of chemical reactions. This attribute is particularly valuable in synthetic chemistry and pharmaceuticals, allowing the formation of more complex molecules.
  • Potential Anticancer Properties: Compounds featuring similar frameworks are often investigated for their anticancer activity. The reactive sites could be exploited to selectively target and damage cancer cells, making this compound a subject of interest in cancer research.
  • Inhibition Mechanisms: The unique dioxo-cyclohexa structure allows for interactions with specific biological pathways, which could lead to the inhibition of certain enzymes or receptors, showcasing potential therapeutic applications.
  • Structure-Activity Relationship (SAR): Understanding how structural variations in this compound affect its biological activity is crucial. It paves the way for the design of more effective derivatives that could optimize therapeutic effectiveness and reduce side effects.
  • Emerging Research: Innovative studies are continually emerging, shedding light on both the pharmacodynamics and pharmacokinetics of this compound, enhancing our understanding of its mechanism of action.

In summary, 2-[2,5-bis(aziridin-1-yl)-4-methyl-3,6-dioxo-cyclohexa-1,4-dien-1-yl]-2-methoxy-ethyl carbamate serves as an inspiring example of how complex organic compounds can bridge the gap between chemical synthesis and practical medicinal applications. Its diverse properties not only ignite curiosity among chemists but also suggest promising avenues for future research in drug development.

Synonyms
carboquone
Esquinon
Carbazilquinone
24279-91-2
Carbazilequinone
Carbaziloquinone
Carboquonum
Carboquona
Carboquone [INN:JAN]
Carboquonum [INN-Latin]
Carboquona [INN-Spanish]
carbocuona
CCRIS 2748
CS 310
NSC 134679
BRN 1400765
DTXSID8046870
CARBOQUONE [MI]
CARBOQUONE [INN]
CARBOQUONE [JAN]
CARBOQUONE [MART.]
CARBOQUONE [WHO-DD]
1CB0HBT12C
2,5-Bis(1-aziridinyl)-3-(2-hydroxy-1-methoxyethyl)-6-methyl-p-benzoquinone carbamate (ester)
MLS002703012
DTXCID6026870
5-20-01-00076 (Beilstein Handbook Reference)
NSC134679
2,5-Bis(1-aziridinyl)-3-(2-carbamoyloxy-1-methoxyethyl)-6-methyl-1,4-benzoquinone
p-Benzoquinone, 2,5-bis(1-aziridinyl)-3-(2-hydroxy-1-methoxyethyl)-6-methyl-, carbamate (ester)
[2-[2,5-bis(aziridin-1-yl)-4-methyl-3,6-dioxocyclohexa-1,4-dien-1-yl]-2-methoxyethyl] carbamate
2-(2-((Aminocarbonyl)oxy)-1-methoxyethyl)-3,6-bis(1-aziridinyl)-5-methyl-2,5-cyclohexadiene-1,4-dione
Carboquonum (INN-Latin)
Carboquona (INN-Spanish)
CARBOQUONE (MART.)
Carboquinone
2-(2,5-di(aziridin-1-yl)-4-methyl-3,6-dioxocyclohexa-1,4-dien-1-yl)-2-methoxyethyl carbamate
UNII-1CB0HBT12C
2,5-bis(1-aziridinyl)-3-(2-(carbamoyloxy)-1-methoxyethyl)-6-methyl-p-benzoquinone
2,5-bis(1-aziridinyl)-3-[2-(carbamoyloxy)-1-methoxyethyl]-6-methyl-p-benzoquinone
NCGC00181140-01
Esquinon (TN)
2, carbamate ester
Carboquone (JAN/INN)
SCHEMBL8079
CHEMBL443014
CHEBI:31356
L01AC03
Tox21_112746
DB13677
NSC-134679
2,5-Cyclohexadiene-1,4-dione, 2-(2-((aminocarbonyl)oxy)-1-methoxyethyl)-3,6-bis(1-aziridinyl)-5-methyl-
NCI60_000771
SMR001566820
CAS-24279-91-2
NS00125301
D01270
Q5038065
2,4-dione, 2,5-bis(1-aziridinyl)-6 (2-hydroxy-1-methoxyethyl)-3-methyl-, carbamate
2,4-dione, 2-[2-[(aminocarbonyl)oxy]-1-methoxyethyl]-3,6-bis(1-aziridinyl)-5-methyl-
[2-[2,5-bis(aziridin-1-yl)-4-methyl-3,6-dioxo-cyclohexa-1,4-dien-1-yl]-2-methoxy-ethyl] carbamate
2,5-Bis(1-aziridinyl)-3-(2-hydroxy-1- methoxyethyl)-6-methyl-1,4-benzoquinone, carbamate (ester)
p-Benzoquinone,5-bis(1-aziridinyl)-3-(2-hydroxy-1-methoxyethyl)-6-methyl-, carbamate (ester)