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Ambroxol hydrochloride

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Identification
Molecular formula
C13H19Br2ClN2O
CAS number
89788-89-2
IUPAC name
2-[(2,6-dibromophenyl)carbamoyloxy]ethyl-diethyl-ammonium;chloride
State
State

At room temperature, ambroxol hydrochloride is in a solid state, specifically appearing as a crystalline powder.

Melting point (Celsius)
248.00
Melting point (Kelvin)
521.00
Boiling point (Celsius)
310.00
Boiling point (Kelvin)
583.00
General information
Molecular weight
414.57g/mol
Molar mass
414.5690g/mol
Density
1.4000g/cm3
Appearence

Ambroxol hydrochloride typically appears as a white to off-white crystalline powder. It is practically odorless or has a very faint odor.

Comment on solubility

Solubility of 2-[(2,6-dibromophenyl)carbamoyloxy]ethyl-diethyl-ammonium;chloride

The compound 2-[(2,6-dibromophenyl)carbamoyloxy]ethyl-diethyl-ammonium;chloride showcases some intriguing solubility characteristics influenced by its quaternary ammonium structure. Here are several key points regarding its solubility:

  • Aqueous Solubility: This compound is generally soluble in water, primarily due to the presence of the quaternary ammonium group, which creates a positive charge that enhances interaction with polar solvents.
  • Organic Solvents: It is also expected to be soluble in various polar organic solvents, like methanol and ethanol, which can facilitate its dissolution by stabilizing the charged species.
  • Temperature Dependence: The solubility may increase with temperature; thus, heating might be beneficial for achieving higher concentrations in solution.
  • Influence of Anions: The chloride ion, being a small and highly soluble anion, contributes positively to the overall solubility of the compound in aqueous environments.

However, it's essential to note that the presence of the bulky (2,6-dibromophenyl) group may introduce steric hindrance, potentially affecting complete solubility under certain conditions. As always, empirical testing is crucial to determine the precise solubility profile under various environmental contexts.

In summary, the solubility of 2-[(2,6-dibromophenyl)carbamoyloxy]ethyl-diethyl-ammonium;chloride is predominantly aligned with its structural features, creating a fascinating interplay between structural attributes and solvent characteristics.

Interesting facts

Interesting Facts About 2-[(2,6-dibromophenyl)carbamoyloxy]ethyl-diethyl-ammonium;chloride

The compound 2-[(2,6-dibromophenyl)carbamoyloxy]ethyl-diethyl-ammonium;chloride is part of the fascinating world of quaternary ammonium compounds. These compounds are characterized by their nitrogen atom that is bonded to four organic groups, resulting in positive charges which lead to unique properties.

Key Highlights:

  • Biological Activity: Many quaternary ammonium compounds, including this one, exhibit interesting biological activities, making them potential candidates for pharmaceutical applications. Research in this area is ongoing to evaluate their effectiveness in different biological processes.
  • Antimicrobial Properties: The presence of the dibromophenyl group suggests that this compound may possess notable antimicrobial properties, providing insight into its potential use in disinfectants and antiseptics.
  • Electrolytic Nature: Being a quaternary ammonium salt, this compound is likely soluble in water, which enhances its ability to interact with various biological systems and substrates.
  • Structure-Activity Relationship (SAR): Understanding the structure of this compound can help scientists design derivatives that improve efficacy or reduce toxicity. SAR studies often guide researchers in optimizing chemical structures for desired biological effects.

In the field of medicinal chemistry, compounds like this are often synthesized to explore their potential as therapeutic agents. The exploration of their mechanisms of action can lead to the development of new drugs with improved efficacy and selectivity. Moreover, the unique properties introduced by substituents like the dibromophenyl can lead to innovative solutions in various applications.

As with many chemicals, safety precautions are essential while handling. Always consult material safety data sheets (MSDS) and follow laboratory safety protocols.

In summary, 2-[(2,6-dibromophenyl)carbamoyloxy]ethyl-diethyl-ammonium;chloride showcases the interdisciplinary nature of chemistry, bridging the realms of organic synthesis, biology, and pharmacology. Its unique attributes may pave the way for exciting developments in both scientific research and practical applications.