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Lidocaine hydrochloride

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Identification
Molecular formula
C14H23ClN2O
CAS number
6108-05-0
IUPAC name
[2-(2,6-dimethylanilino)-1-methyl-2-oxo-ethyl]-[2-(2,6-dimethylanilino)-2-oxo-ethyl]-dimethyl-ammonium;chloride
State
State
At room temperature, lidocaine hydrochloride is in a solid state. It is stable under normal conditions and is commonly stored in dry, cool conditions away from light.
Melting point (Celsius)
74.00
Melting point (Kelvin)
347.15
Boiling point (Celsius)
422.00
Boiling point (Kelvin)
695.15
General information
Molecular weight
270.80g/mol
Molar mass
288.8180g/mol
Density
1.1000g/cm3
Appearence
Lidocaine hydrochloride is typically a white, crystalline powder. It is odorless and has a slightly bitter taste. The compound is often supplied in solutions or gels as it is used in various medical and dental applications.
Comment on solubility

Solubility of [2-(2,6-dimethylanilino)-1-methyl-2-oxo-ethyl]-[2-(2,6-dimethylanilino)-2-oxo-ethyl]-dimethyl-ammonium;chloride

The solubility of the compound [2-(2,6-dimethylanilino)-1-methyl-2-oxo-ethyl]-[2-(2,6-dimethylanilino)-2-oxo-ethyl]-dimethyl-ammonium;chloride is influenced by several key factors, including its structural characteristics and the nature of its ionic components.

Factors affecting solubility:

  • Polarity: The presence of multiple polar functional groups in the compound increases its potential to interact with polar solvents like water.
  • Ionization: Being a quaternary ammonium salt, it readily dissociates into ions in solution, which enhances its solubility in polar solvents.
  • Hydrophobic interactions: The 2,6-dimethyl groups contribute to hydrophobic regions, potentially decreasing solubility in non-polar solvents.

In general, quaternary ammonium compounds such as this one are known for their high solubility in water due to their ionic nature. However, the degree of solubility can vary widely depending on the following:

  1. Concentration: Higher concentrations may exceed the solubility limits.
  2. Temperature: Increasing temperature usually enhances solubility for salts.
  3. Presence of other substances: The effect of co-solvents or competing ions in the solution can also alter solubility.

Therefore, while [2-(2,6-dimethylanilino)-1-methyl-2-oxo-ethyl]-[2-(2,6-dimethylanilino)-2-oxo-ethyl]-dimethyl-ammonium;chloride is generally soluble in polar media, comprehensive evaluation through experimental methods is essential for precise solubility predictions under varying conditions.

Interesting facts

Interesting Facts about [2-(2,6-dimethylanilino)-1-methyl-2-oxo-ethyl]-[2-(2,6-dimethylanilino)-2-oxo-ethyl]-dimethyl-ammonium;chloride

This compound is an intriguing member of the quaternary ammonium compounds, which are notable for their broad range of applications in both industry and research. Here are some interesting points about this compound:

  • Structure and Functionality: The complex structure containing dimethylanilino groups indicates a functional affinity towards biological systems, making it a valuable candidate in pharmacological studies.
  • Quaternary Ammonium Nature: As a quaternary ammonium compound, it possesses unique properties such as high solubility in water and the ability to act as a surfactant, which can enhance its utility in various formulations.
  • Biological Implications: Compounds of this class are often investigated for antimicrobial properties, potentially paving the way for new disinfectants or antiseptic agents.
  • Research Applications: This compound could serve as an important tool in organic synthesis, especially in reactions requiring specified sterics and electronics due to its bulky groups.
  • Safety and Handling: Like many chemical substances, especially those involving quaternary ammonium structures, it requires careful handling in the laboratory to ensure safety and minimize exposure risks.

Overall, its unique combination of structural characteristics and chemical properties makes it a fascinating compound for ongoing research and application in various fields.

Synonyms
4169-35-1
Dimethyl(1-(2,6-xylylcarbamoyl)ethyl)((2,6-xylylcarbamoyl)methyl)ammonium chloride
Ammonium, dimethyl(1-(2,6-xylylcarbamoyl)ethyl)((2,6-xylylcarbamoyl)methyl)-, chloride
[2-(2,6-dimethylanilino)-2-oxoethyl]-[1-(2,6-dimethylanilino)-1-oxopropan-2-yl]-dimethylazanium chloride