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Procainamide Hydrochloride

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Identification
Molecular formula
C13H21ClN2O2
CAS number
51-06-9
IUPAC name
[2-(2,6-dimethylanilino)-2-oxo-ethyl]-(2-hydroxypropyl)ammonium;chloride
State
State

At room temperature, procainamide hydrochloride is in a solid state. Due to its crystalline nature, it is typically stored in a tightly sealed container to prevent moisture absorption which could alter its stability and efficacy. It remains stable under standard conditions of storage and handling.

Melting point (Celsius)
167.50
Melting point (Kelvin)
440.65
Boiling point (Celsius)
228.60
Boiling point (Kelvin)
501.75
General information
Molecular weight
271.80g/mol
Molar mass
271.7960g/mol
Density
1.1950g/cm3
Appearence

Procainamide hydrochloride typically appears as a white to off-white, crystalline powder. It is odorless and has a bitter taste. The compound is highly soluble in water, allowing it to be used effectively in aqueous solutions for various therapeutic applications.

Comment on solubility

Solubility of [2-(2,6-dimethylanilino)-2-oxo-ethyl]-(2-hydroxypropyl)ammonium; chloride

The solubility of the compound [2-(2,6-dimethylanilino)-2-oxo-ethyl]-(2-hydroxypropyl)ammonium; chloride can be influenced by various factors due to its complex structure. Generally, this compound can be categorized under *ammonium salts*, which often exhibit interesting solubility characteristics.

Factors Affecting Solubility

  • Polarity: The presence of ionic characteristics in the chloride group enhances its capacity to dissolve in polar solvents, particularly water.
  • Hydrophilic Groups: The hydroxypropyl moiety is expected to contribute to the overall solubility, engaging in hydrogen bonding with water molecules.
  • Temperature: Increasing the temperature typically improves the solubility of ammonium salts, thus it will be likely more soluble at higher temperatures.

However, it's crucial to note that the presence of the dimethylamino and oxo groups may introduce less favorable interactions for solubility. In summary, while [2-(2,6-dimethylanilino)-2-oxo-ethyl]-(2-hydroxypropyl)ammonium; chloride is likely soluble in water due to its ionic nature, qualitative assessments in various solvents may reveal varying degrees of solubility based on environmental factors and structure-specific interactions.

Interesting facts

Interesting Facts about [2-(2,6-Dimethylanilino)-2-oxo-ethyl]-(2-hydroxypropyl)ammonium; Chloride

This compound, with its intriguing structure, is a prime example of how complex chemistry can yield compounds with unique properties and applications. Here are some interesting aspects of this compound:

  • Dual Functionality: The presence of both the ammonium group and the hydroxypropyl moiety suggests a potential for dual functionality, making it a subject of interest in both medicinal chemistry and material science.
  • Protein Interaction: Compounds like this one can be investigated for their ability to stabilize proteins or alter their function, which has implications in drug design and development.
  • Antimicrobial Properties: There is a growing interest in similar compounds for their antimicrobial properties, which could be invaluable in pharmaceuticals, particularly in the fight against resistant bacteria.
  • Synthetic Versatility: This compound showcases potential routes for synthesis due to its complex structure incorporating both aromatic and aliphatic elements. This could be of interest to chemists focusing on synthesizing new materials.
  • Research Applications: Due to its chemical structure, this compound could serve as a useful intermediate in the synthesis of various biologically active molecules, thus contributing to ongoing research in organic chemistry.

In summary, while [2-(2,6-dimethylanilino)-2-oxo-ethyl]-(2-hydroxypropyl)ammonium; chloride may seem intricate and specialized, its diverse potential applications and implications make it a fascinating subject for further study in the chemical sciences. The ongoing research into its properties could reveal even more about its usefulness and applications.

Synonyms
20846-41-7
2-(2-Hydroxypropylamino)-2',6'-dimethylacetanilide hydrochloride
2',6'-ACETOXYLIDIDE, 2-((2-HYDROXYPROPYL)AMINO)-, HYDROCHLORIDE
Acetamide, N-(2,6-dimethylphenyl)-2-((2-hydroxypropyl)amino)-, hydrochloride
RefChem:241066