Skip to main content

Oxymetazoline hydrochloride

ADVERTISEMENT
Identification
Molecular formula
C16H24ClN3O
CAS number
2315-02-8
IUPAC name
2-[(2,6-dimethylphenoxy)methyl]-4,5-dihydro-1H-imidazol-1-ium;chloride
State
State

At room temperature, Oxymetazoline hydrochloride is in a solid state. It is a stable compound under standard conditions, which is crucial for its use in various pharmaceutical applications.

Melting point (Celsius)
265.00
Melting point (Kelvin)
538.15
Boiling point (Celsius)
200.00
Boiling point (Kelvin)
473.15
General information
Molecular weight
296.80g/mol
Molar mass
297.8180g/mol
Density
1.0500g/cm3
Appearence

Oxymetazoline hydrochloride appears as a white to off-white crystalline powder. It is known for its characteristic crystalline structure and is often odorless. The compound is highly soluble in water, leading to clear solutions when dissolved.

Comment on solubility

Solubility of 2-[(2,6-dimethylphenoxy)methyl]-4,5-dihydro-1H-imidazol-1-ium;chloride

The compound 2-[(2,6-dimethylphenoxy)methyl]-4,5-dihydro-1H-imidazol-1-ium;chloride exhibits unique solubility characteristics, which are crucial in determining its practical applications in various fields. Solubility is influenced by several factors, and for this compound, we observe the following:

  • Polarity: The presence of an imidazolium moiety generally enhances solubility in polar solvents due to its ionic nature.
  • Hydrophobic Phenyl Group: The 2,6-dimethylphenoxy group adds hydrophobic characteristics, potentially reducing solubility in highly polar solvents.
  • Solvent Choice: This compound is likely more soluble in protic solvents like water and alcohols, but less soluble in nonpolar solvents.

In essence, “Like dissolves like” applies here, meaning that the solubility of this compound will be favored in environments that mimic its chemical structure. Additionally, the presence of chloride ions can affect the overall solubility due to their ability to engage in ion-dipole interactions with polar solvents.

In summary, understanding the solubility of this compound not only facilitates its synthesis and utilization but also enhances the development of its applications in pharmaceuticals and agrochemicals, where solubility plays a key role in bioavailability and efficacy.

Interesting facts

Interesting Facts about 2-[(2,6-Dimethylphenoxy)methyl]-4,5-dihydro-1H-imidazol-1-ium; Chloride

This compound, often referred to for its unique structure as a member of the imidazolium salts, has captured the attention of researchers due to its intriguing properties and potential applications. Here are some highlights:

  • Imidazolium Salt: The imidazolium structure is significant in various fields, including organic synthesis and catalysis. Its aromaticity and partial positive charge contribute to its unique reactivity.
  • Biological Activity: Compounds containing the imidazolium moiety have been researched for their biological properties, demonstrating potential as antimicrobial agents.
  • Solubility and Ionic Nature: As a salt, it exhibits solubility in aqueous and organic solvents, making it versatile for various chemical reactions, including those in ionic liquid technology.
  • Role in Organic Synthesis: The presence of the 2,6-dimethylphenoxy group adds steric hindrance and electron-donating characteristics, making this compound interesting for synthesis and as a ligand in coordination chemistry.
  • Research Potential: Ongoing studies are exploring its use as a catalyst in organic reactions, as well as in the development of new materials.

Scientists are excited about the possibilities that compounds like this one can bring to fields such as medicinal chemistry, materials science, and green chemistry. As Albert Einstein once said, "The important thing is not to stop questioning. Curiosity has its own reason for existence." This compound embodies that spirit of inquiry, inviting further exploration into its properties and applications.

In conclusion, 2-[(2,6-dimethylphenoxy)methyl]-4,5-dihydro-1H-imidazol-1-ium; chloride is not just a chemical entity; it represents a gateway to understanding complex chemical phenomena and developing innovative solutions in various scientific fields.

Synonyms
NSC 173768
2-((2,6-Dimethylphenoxy)methyl)-2-imidazoline hydrochloride
2-IMIDAZOLINE, 2-((2,6-XYLYLOXY)METHYL)-, HYDROCHLORIDE
RefChem:261992
21244-85-9