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Desmethylprodine (MPPP)

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Identification
Molecular formula
C21H25NO
CAS number
468-81-9
IUPAC name
2-(2,6-diphenyl-4-pyrrolidin-1-yl-cyclohexyl)pyridine
State
State

At room temperature, Desmethylprodine is generally found in a liquid state. In some preparations, it may solidify, especially in cooler conditions, to form a waxy or crystalline solid. It is crucial to note the physical state before handling, as it influences the methods of application and safety precautions required.

Melting point (Celsius)
131.80
Melting point (Kelvin)
404.95
Boiling point (Celsius)
155.90
Boiling point (Kelvin)
429.05
General information
Molecular weight
311.43g/mol
Molar mass
313.4500g/mol
Density
1.0100g/cm3
Appearence

Desmethylprodine is typically a colorless or pale yellow liquid. However, its appearance may vary as it can also come in the form of an oily liquid or sometimes as a solid, depending on the manufacturing process and conditions. The substance should be handled carefully due to its potential as a synthetic opioid.

Comment on solubility

Solubility of 2-(2,6-diphenyl-4-pyrrolidin-1-yl-cyclohexyl)pyridine

The solubility of 2-(2,6-diphenyl-4-pyrrolidin-1-yl-cyclohexyl)pyridine in various solvents can be quite intriguing due to its complex structure. Understanding its solubility profile is essential for applications in medicinal chemistry and material science. Key factors influencing its solubility include:

  • Polarity: The presence of multiple aromatic rings may lead to lower solubility in polar solvents, while it could dissolve better in non-polar organic solvents.
  • Structural Congruence: Compounds with similar structural features often exhibit better solubility in their respective solvents. This emphasizes the importance of solvent selection.
  • Hydrogen Bonding: The nitrogen atoms within the pyridine and pyrrolidine groups can participate in hydrogen bonding, which can enhance solubility in protic solvents.

It is crucial to consider the following solubility scenarios:

  1. High Solubility: Can be expected in solvents like DMSO or DMF, which can stabilize the compound through strong dipole-dipole interactions.
  2. Moderate Solubility: Might be found in chloroform and toluene owing to the aromatic interactions.
  3. Low Solubility: Expected in water and similar polar solvents due to poor interaction with the compound's hydrophobic regions.

In conclusion, the solubility of this compound is not only influenced by its inherent chemical structure but also by the nature of the solvent used. This interplay is crucial for practical applications, particularly in formulation and synthesis.

Interesting facts

Interesting Facts about 2-(2,6-diphenyl-4-pyrrolidin-1-yl-cyclohexyl)pyridine

The compound 2-(2,6-diphenyl-4-pyrrolidin-1-yl-cyclohexyl)pyridine is a fascinating organic molecule that belongs to the class of pyridines. Known for its complex structure, it presents a unique blend of cyclic and aromatic systems that contribute to its structural and functional diversity. Here are some captivating insights:

Chemical Significance

  • Biological Activity: This compound has been researched for its potential biological activities, including neuroprotective effects and as a receptor modulator, which could pave the way for new therapeutic agents.
  • Pharmaceutical Potential: Its intricately designed structure enhances the likelihood of interactions with biological targets, making it a candidate for drug development.
  • Research Interest: Scientists are increasingly interested in compounds like this due to their potential implications in neuroscience and medicinal chemistry.

Structural Attributes

  • Substituent Diversity: The presence of multiple phenyl groups and a pyrrolidine ring contributes to its overall stability and electronic properties.
  • Flexibility: The cyclohexyl and pyrrolidine components provide an interesting level of flexibility that may impact molecular interactions in biological systems.

Applications in Science

This compound's unique properties make it a subject of interest not only in organic chemistry but also in medicinal chemistry and pharmacology. As scientists explore its reactivity and interactions, they may uncover new applications that could change the landscape of drug discovery.

As innovations in chemical synthesis continue to evolve, understanding the characteristics and functionalities of such compounds can lead to exciting breakthroughs in various scientific fields, including materials science and medicinal chemistry.

In conclusion, 2-(2,6-diphenyl-4-pyrrolidin-1-yl-cyclohexyl)pyridine encapsulates the complexities and wonders of organic compounds, reminding us of the endless possibilities that lie within chemical research.

Synonyms
10462-05-2
SU 15049
SU-15049
Pyridine, 2-(2,6-diphenyl-4-(1-pyrrolidinyl)cyclohexyl)-
RefChem:186190
2,6-Diphenyl-4-(1-pyrrolidinyl)-1-pyridinylcyclohexane
2-(2,6-diphenyl-4-pyrrolidin-1-ylcyclohexyl)pyridine
DTXSID20909061
2-[2~5~-(Pyrrolidin-1-yl)-2~1~,2~2~,2~3~,2~4~,2~5~,2~6~-hexahydro[1~1~,2~1~:2~3~,3~1~-terphenyl]-2~2~-yl]pyridine