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Amiodarone

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Identification
Molecular formula
C25H29NO
CAS number
1951-25-3
IUPAC name
2-[3-(1-piperidyl)propyl]tricyclo[9.4.0.03,8]pentadeca-1(15),3,5,7,11,13-hexaen-2-ol
State
State

At room temperature, Amiodarone is typically in a solid state.

Melting point (Celsius)
158.00
Melting point (Kelvin)
431.15
Boiling point (Celsius)
460.00
Boiling point (Kelvin)
733.15
General information
Molecular weight
645.32g/mol
Molar mass
645.3210g/mol
Density
1.1893g/cm3
Appearence

Amiodarone is typically a white or slightly yellow crystalline powder.

Comment on solubility

Solubility Characteristics of 2-[3-(1-piperidyl)propyl]tricyclo[9.4.0.03,8]pentadeca-1(15),3,5,7,11,13-hexaen-2-ol

The solubility of 2-[3-(1-piperidyl)propyl]tricyclo[9.4.0.03,8]pentadeca-1(15),3,5,7,11,13-hexaen-2-ol can be quite complex due to its unique structural features. Here are key points to consider:

  • Polarity: The presence of multiple functional groups can affect the overall polarity of the compound, influencing its solubility in various solvents.
  • Solvent Compatibility: It may demonstrate differing solubility profiles in polar solvents (like water or ethanol) versus non-polar solvents (such as hexane or toluene).
  • Hydrogen Bonding: The hydroxyl (-OH) group can engage in hydrogen bonding, increasing solubility in polar solvents.
  • Hydrophobic Interactions: The tricyclic structure may contribute to hydrophobic characteristics, potentially decreasing solubility in aqueous solutions.

In summary, the solubility of this compound is a balance between hydrophilic and hydrophobic interactions. As a result, it may be more soluble in organic solvents where hydrophobic interactions are favored, while exhibiting limited solubility in water. This dual nature can be crucial for its applications in medicinal chemistry and formulation design.

Interesting facts

Interesting Facts about 2-[3-(1-piperidyl)propyl]tricyclo[9.4.0.03,8]pentadeca-1(15),3,5,7,11,13-hexaen-2-ol

This intriguing compound, known for its complex structure and unique properties, offers a wealth of exploration for both chemists and biology enthusiasts alike. Here are some compelling aspects that make this compound noteworthy:

  • Structural Complexity: The molecule features a tricyclic framework, which is a type of structure characterized by three connected rings. This level of complexity often implies interesting chemical behavior and biological activity.
  • Biological Relevance: Compounds similar to this one are often investigated for their potential pharmacological effects. They may influence various biological pathways, making them candidates for drug development or therapeutic interventions.
  • Piperidine Influence: The presence of a piperidine ring, a six-membered ring containing nitrogen, is known to impart interesting biological properties, including potential antidepressant or analgesic effects.
  • Unsaturation and Reactivity: With multiple double bonds indicated by the hexaen nomenclature, this compound is expected to participate in a range of reactions, which could be harnessed in synthetic chemistry.
  • Applications in Research: Scientists often explore such compounds in the context of molecular biology to understand their mechanisms of action and interaction with biological targets, aiding in the design of new therapeutic agents.

In conclusion, the study of 2-[3-(1-piperidyl)propyl]tricyclo[9.4.0.03,8]pentadeca-1(15),3,5,7,11,13-hexaen-2-ol not only enhances our comprehension of chemical structures but also opens avenues for innovation in medicinal chemistry.


Synonyms
19661-02-0
BRN 1262922
5H-DIBENZO(a,d)CYCLOHEPTEN-5-OL, 10,11-DIHYDRO-5-(3-PIPERIDINOPROPYL)-
DTXSID10173330
10,11-Dihydro-5-(3-piperidinopropyl)-5H-dibenzo(a,d)cyclohepten-5-ol
5-20-02-00256 (Beilstein Handbook Reference)
10,11-Dihydro-5-(3-piperidinopropyl)-5H-dibenzo[a,d]cyclohepten-5-ol
DTXCID6095821
RefChem:305529
2-(3-piperidin-1-ylpropyl)tricyclo[9.4.0.03,8]pentadeca-1(15),3,5,7,11,13-hexaen-2-ol
AKOS005216065
AE-641/37091025
5-[3-(1-piperidinyl)propyl]-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-ol