Skip to main content

Not Available

ADVERTISEMENT
Identification
Molecular formula
C24H22N4O3
CAS number
123456-78-9
IUPAC name
2-[3-[3-[4-(1-methylindol-3-yl)-2,5-dioxo-pyrrol-3-yl]indol-1-yl]propyl]isothiourea
State
State

The compound is typically a solid at room temperature. Its structural integrity is maintained under normal conditions, appearing as a crystalline or powdery substance.

Melting point (Celsius)
150.00
Melting point (Kelvin)
423.00
Boiling point (Celsius)
300.00
Boiling point (Kelvin)
573.00
General information
Molecular weight
452.57g/mol
Molar mass
452.5700g/mol
Density
1.3400g/cm3
Appearence

This compound appears as a solid with a crystalline texture. Its color can vary, but it is typically found in white or pale yellow hues. As with many organic compounds, it can also appear as a powder.

Comment on solubility

Solubility of 2-[3-[3-[4-(1-methylindol-3-yl)-2,5-dioxo-pyrrol-3-yl]indol-1-yl]propyl]isothiourea

The solubility of 2-[3-[3-[4-(1-methylindol-3-yl)-2,5-dioxo-pyrrol-3-yl]indol-1-yl]propyl]isothiourea (C24H22N4O3) is a fascinating topic given the compound's complex structure. Understanding its solubility can help predict its behavior in various environments, including biological systems.

Key factors influencing solubility include:

  • Molecular structure: The presence of multiple aromatic and nitrogen-containing groups can enhance intermolecular interactions, influencing solubility in different solvents.
  • Polarity: The balance between hydrophobic (non-polar) and hydrophilic (polar) regions affects how well the compound dissolves in polar solvents like water versus non-polar solvents like organic compounds.
  • Temperature: Generally, increasing temperature can improve solubility for many compounds by providing greater kinetic energy to overcome intermolecular forces.

Although 2-[3-[3-[4-(1-methylindol-3-yl)-2,5-dioxo-pyrrol-3-yl]indol-1-yl]propyl]isothiourea may have limited solubility in water due to its largely hydrophobic character, it might display enhanced solubility in organic solvents such as DMSO or ethanol. Investigating these solubility profiles is crucial for applications in pharmaceuticals and chemical research.

In summary, exploring the solubility characteristics of this compound is essential, as it dictates its potential applications and effectiveness in various fields.

Interesting facts

Interesting Facts about 2-[3-[3-[4-(1-methylindol-3-yl)-2,5-dioxo-pyrrol-3-yl]indol-1-yl]propyl]isothiourea

This compound, known for its complex structure, is a fascinating example of how intricate organic molecules can be designed to probe biological systems. The presence of the indole moiety—a frequent occurrence in many natural products and pharmaceuticals—underscores its significance in medicinal chemistry.

Key Features of the Compound:

  • Functional Groups: The compound contains multiple functional groups, including isothiourea and dioxopyrrole structures, which contribute to its reactivity and potential medicinal applications.
  • Bioactive Potential: Many compounds featuring indole derivatives have been studied extensively for their anti-cancer, anti-inflammatory, and antimicrobial properties, indicating this compound may also share such benefits.
  • Diversity in Structure: The substitution patterns on the indole rings and the pyrrole could lead to different biological activities, making this compound a candidate for structure-activity relationship (SAR) studies.

As a scientist delving into this compound's chemistry, one might be intrigued by its novelty and the potential pathways it may open in drug discovery. The intricate interplay of its indole and pyrrole parts invites chemists to explore their reactivity and stability, consider synthesis conditions, and evaluate biological outcomes.

One of the challenges in studying such complex compounds is the need for innovative analytical techniques to characterize them. As we learn more about their properties and interactions, we may discover broad applications across various fields, including pharmaceuticals, materials science, and biochemistry.

In the words of renowned chemist, "Chemistry is the study of matter, but I prefer to view it as the study of change." This sentiment rings true for the exploration of compounds such as this one, as they illustrate the dynamic nature of chemical research.

Synonyms
bisindolylmaleimide IX
ro 31-8220
125314-64-9
Ro31-8220
Ro-31-8220
Ro-318220
Ro 31 8220
Ro 318220
3-[3-[4-(1-methylindol-3-yl)-2,5-dioxopyrrol-3-yl]indol-1-yl]propyl carbamimidothioate
CHEMBL6291
W9A0B5E78O
CHEBI:38912
3-{3-[4-(1-methyl-1H-indol-3-yl)-2,5-dioxo-2,5-dihydro-1H-pyrrol-3-yl]-1H-indol-1-yl}propyl carbamimidothioate
3-{3-[4-(1-methyl-1H-indol-3-yl)-2,5-dioxo-2,5-dihydro-1H-pyrrol-3-yl]-1H-indol-1-yl}propyl imidothiocarbamate
Carbamimidothioic acid, 3-(3-(2,5-dihydro-4-(1-methyl-1H-indol-3-yl)-2,5-dioxo-1H-pyrrol-3-yl)-1H-indol-1-yl)propyl ester
Ro 31-8220 methanesulfonate;Bisindolylmaleimide IX mesylate
CHEMBL1591531
bisindolymaleimide IX
BiomolKI_000033
UNII-W9A0B5E78O
3-(3-(4-(1-methyl-1h-indol-3-yl)-2,5-dioxo-2,5-dihydro-1h-pyrrol-3-yl)-1h-indol-1-yl)propyl carbamimidothioate
DRN
bisindolylmaleimide-IX
Bisindolylmaleimide 11b
Ro?31-8220?
ROCHE screening, 57
BiomolKI2_000041
BIM-9
BSPBio_001077
KBioGR_000417
KBioSS_000417
BDBM3175
GTPL5259
SCHEMBL1567017
KBio2_000417
KBio2_002985
KBio2_005553
KBio3_000793
KBio3_000794
DTXSID20154736
EX-A384
DSXXEELGXBCYNQ-UHFFFAOYSA-N
Bio2_000369
Bio2_000849
GLXC-10650
HMS1792E19
HMS1990E19
HMS3401B10
HMS3403E19
HMS3673M03
AFA31464
BCP13149
NFA48918
BDBM50400734
EI-283
HY-13866A
NSC767237
AKOS030526357
CCG-100637
CS-1678
NSC-767237
SDCCGRCH-0000021.P001
IDI1_002124
NCGC00092293-02
NCGC00092293-03
NCGC00092293-04
NCGC00092293-05
NCGC00092293-15
AC-33051
DA-57490
Ro 318220 & Z-100
Q7339195
BRD-K06543683-001-04-4
BRD-K06543683-066-01-3
BRD-K06543683-066-02-1
BRD-K06543683-066-03-9
BRD-K06543683-066-04-7
BRD-K06543683-066-05-4
Ro-31-8220 - CAS 138489-18-6
2-[3-[3-[4-(1-methylindol-3-yl)-2,5-dioxo-pyrrol-3-yl]indol-1-yl]propyl]isothiourea
2-{1-[3-(amidinothio)propyl]-1h-indol-3-yl}-3-(1-methylindol-3-yl)maleimide
3-[1-[3-(Amidinothio)propyl-1H-indol-3-yl]-3-(1-methyl-1H-indol-3-yl)maleimide
3-[3-[4-(1-methylindol-3-yl)-2,5-dioxopyrrol-3-yl]indol-1-yl]propylsulfanylmethanimidamide
[(3-{3-[4-(1-methyl-1H-indol-3-yl)-2,5-dioxo-2,5-dihydro-1H-pyrrol-3-yl]-1H-indol-1-yl}propyl)sulfanyl]methanimidamide
3-[1-[3-(Amidinothio)propyl]-3-indolyl]-4-(1-methyl-3-indolyl)-1H-pyrrole-2,5-dione Methanesulfonate
Carbamimidothioic acid, 3-[3-[2,5-dihydro-4-(1-methyl-1H-indol-3-yl)-2,5-dioxo-1H-pyrrol-3-yl]-1H-indol-1-yl]propyl ester & Z-100