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Flufenamic acid

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Identification
Molecular formula
C14H10NO4
CAS number
530-78-9
IUPAC name
2-[3-(3,4-dimethoxyphenyl)prop-2-enoylamino]benzoic acid
State
State

At room temperature, flufenamic acid is a solid. This compound is known to maintain its solid state under standard atmospheric conditions.

Melting point (Celsius)
134.00
Melting point (Kelvin)
407.20
Boiling point (Celsius)
558.20
Boiling point (Kelvin)
831.30
General information
Molecular weight
281.26g/mol
Molar mass
282.2730g/mol
Density
1.4170g/cm3
Appearence

Flufenamic acid appears as an off-white to yellow crystalline powder. It is known for its characteristic crystalline structure that forms in solid state.

Comment on solubility

Solubility of 2-[3-(3,4-dimethoxyphenyl)prop-2-enoylamino]benzoic Acid

The compound 2-[3-(3,4-dimethoxyphenyl)prop-2-enoylamino]benzoic acid (C14H10NO4) exhibits interesting solubility characteristics influenced by its molecular structure.


Solubility Insights:

  • Polarity: The presence of both aromatic and polar functional groups suggests that the compound may possess moderate to high polarity. This can enhance its solubility in polar solvents like water.
  • Aromatic Interactions: The multiple aromatic groups can facilitate interactions with various organic solvents, potentially allowing solubility in organic solvents such as ethanol or methanol.
  • pH Dependence: As an acid, its solubility may significantly depend on the pH of the solution. At lower pH levels, the compound is likely to remain protonated, enhancing its solubility in aqueous environments.
  • Hydrogen Bonding: The carboxylic acid functional group can form hydrogen bonds, which may increase solubility in alcohols and other hydrogen-bond donating solvents.

In conclusion, while this compound likely exhibits variable solubility depending on the solvent and environmental factors, understanding its solubility characteristics can provide essential insights for its practical applications in various fields, including pharmaceuticals and organic chemistry.

Interesting facts

Interesting Facts about 2-[3-(3,4-dimethoxyphenyl)prop-2-enoylamino]benzoic acid

This fascinating compound, 2-[3-(3,4-dimethoxyphenyl)prop-2-enoylamino]benzoic acid, belongs to the family of benzoic acids and displays a unique structural arrangement that captures the interest of chemists and researchers alike. Here are some intriguing aspects:

  • Diverse Applications: This compound has potential applications in various fields such as pharmaceuticals, biotechnology, and organic synthesis due to its intricate aromatic system.
  • Biological Significance: Compounds similar to this structure often exhibit biological activities, making them a topic of study for drug discovery and medicinal chemistry.
  • Structural Complexity: The presence of both a benzoic acid moiety and an amide functionality enhances its reactivity and solubility properties, which are essential for therapeutic efficacy.
  • Analytical Techniques: The characterization of this compound can be achieved through modern analytical techniques such as NMR, IR, and mass spectrometry, providing valuable insight into molecular behavior.
  • Research Potential: Due to its unique structure, this compound is a compelling subject for research in the development of targeted therapies for various diseases.

In conclusion, 2-[3-(3,4-dimethoxyphenyl)prop-2-enoylamino]benzoic acid not only presents a complex chemical makeup but also holds numerous possibilities for practical applications and research explorations in the field of chemistry.

Synonyms
Tranilast trans-
DTXSID7023693
MK 341;SB 252218
Spectrum2_000042
Spectrum3_001961
SPBio_000163
Benzoic acid,2-[[3-(3-methoxy-4-propoxyphenyl)-1-oxo-2-propenyl]amino]-
CHEMBL3184283
KBio3_002905
NZHGWWWHIYHZNX-UHFFFAOYSA-N
HMS3267I14
HMS3372C04
HMS3393F05
HMS3654F08
53902-17-3
AKOS026750403
3,4-dimethoxy-cinnamoyl-anthranilic acid
NCGC00018185-07
NCGC00018185-12
SY030160
T2935
N-(3',4'-dimethoxycinnamoyl)-anthranilic acid
N-(3', 4'-dimethoxycinnamoyl)-anthranilic acid
N-(3a(2),4a(2)-Dimethoxycinnamoyl)anthranilic acid
2-[[3-(3,4-dimethoxyphenyl)acryloyl]amino]benzoic acid
2-[[3-(3,4-dimethoxyphenyl)-1-oxo-2-propen-1-yl]amino]-benzoic acid