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2-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propoxy]ethanol

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Identification
Molecular formula
C16H26N2O3
CAS number
75872-66-1
IUPAC name
2-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propoxy]ethanol
State
State

At room temperature, this compound is usually in a liquid state.

Melting point (Celsius)
8.00
Melting point (Kelvin)
281.15
Boiling point (Celsius)
360.00
Boiling point (Kelvin)
633.15
General information
Molecular weight
296.40g/mol
Molar mass
296.3960g/mol
Density
1.0900g/cm3
Appearence

This compound typically appears as a colorless to light yellow liquid. It is often clear and may have a slight odor characteristic to its chemical structure.

Comment on solubility

Solubility Insights for 2-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propoxy]ethanol

The solubility of 2-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propoxy]ethanol in various solvents can offer intriguing details about its chemical nature. This compound possesses multiple functional groups that influence its interaction with solvents and determine its solubility profile.

Factors Influencing Solubility

Several factors play a crucial role in determining the solubility of this compound:

  • Polarity: The presence of hydroxyl (–OH) and ether (–O–) groups increases polarity, making it more soluble in polar solvents like water.
  • Hydrogen Bonding: The ability of the hydroxyl group to form hydrogen bonds can significantly enhance solubility in protic solvents.
  • Hydrophobic Regions: The methoxyphenyl and piperazine rings contribute hydrophobic characteristics, which may limit solubility in highly polar environments.

Solubility Characteristics

When considering the overall solubility of this compound, a few specific points are noteworthy:

  • Water solubility is likely significant due to the presence of the hydroxyl group.
  • Solubility in organic solvents such as ethanol and methanol may also be favorable, attributing to its mixed polarity.
  • It may exhibit lower solubility in non-polar solvents due to the hydrophobic nature of some molecular regions.

Ultimately, understanding the solubility of 2-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propoxy]ethanol is essential for various applications, including pharmaceutical formulations, where the solubility characteristics dictate its bioavailability and therapeutic efficacy.

Interesting facts

Interesting Facts About 2-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propoxy]ethanol

2-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propoxy]ethanol is a fascinating compound with a variety of applications in the field of medicinal chemistry. Here are some intriguing aspects regarding this unique chemical:

  • Pharmacological Relevance: This compound features a piperazine ring, which is a common structural motif in many pharmaceuticals, especially in antidepressants and antipsychotics. Its structure can influence how drugs interact with neurotransmitter receptors in the brain.
  • Structure-Activity Relationship (SAR): The presence of the 2-methoxyphenyl group enhances the compound's ability to interact with biological targets. Modifications in this structure can significantly affect the compound's activity and selectivity.
  • Research Applications: Extensive research has been conducted to explore the efficacy of this compound in treating various psychological disorders. Studies often focus on how variations in the piperazine moiety affect the compound's bioactivity.
  • Analytical Chemistry: Techniques like High-Performance Liquid Chromatography (HPLC) and Nuclear Magnetic Resonance (NMR) spectroscopy are utilized to study and characterize this compound. These analyses help in understanding its purity and structural integrity.
  • Future Perspectives: Researchers are continually investigating novel compounds similar in structure to further optimize therapeutic potential. Compounds like this one represent a crucial segment of the drug discovery pipeline and are essential for developing more effective treatments for mental health disorders.

In conclusion, the compound 2-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propoxy]ethanol serves as a significant example of how specific structural elements contribute to complex interactions within biological systems. As a chemistry student or scientist, exploring such compounds opens a gateway to understanding the intricate relationship between chemical structure and biological function.

Synonyms
G6S09HF68X
UNII-G6S09HF68X
2-(3-(4-(2-Methoxyphenyl)piperazin-1-yl)propoxy)ethanol
93162-31-3
1-(o-Methoxyphenyl)-4-((3 beta hydroxyethoxy)propyl)piperazine
Ethanol, 2-(3-(4-(2-methoxyphenyl)-1-piperazinyl)propoxy)-
AKOS024323686
2-{3-[4-(2-methoxyphenyl)-1-piperazinyl]propoxy}ethanol