Interesting facts
Interesting Facts about 2-[3-[4-(3-chlorophenyl)piperazin-1-yl]propyl]-5-ethyl-4-(2-phenoxyethyl)-1,2,4-triazol-3-one
This compound is a fascinating member of the triazole family, notable for its structural complexity and potential applications in pharmaceutical science. Here are some intriguing insights into this compound:
- Pharmacological Interest: Compounds of this kind are often investigated for their potential therapeutic effects, particularly in the realm of neurological disorders and mental health treatments. The presence of the piperazine ring is known to enhance interactions with various neurotransmitter receptors.
- Unique Structural Features: The incorporation of a chlorophenyl group not only influences the compound's pharmacodynamics but also its binding affinity, making it an interesting subject for drug design and development studies.
- Synthesis and Characterization: The synthesis of such complex molecules often involves multi-step reactions, including condensation, cyclization, and functional group modifications, which can be challenging yet rewarding for chemists. Understanding these processes is key to discovering new compounds.
- Research Applications: Scientists are constantly exploring the properties of triazoles. This compound may show promise in antifungal or antibacterial applications due to the efficacy of triazole derivatives in targeting biological pathways.
- Interdisciplinary Connections: The study of this compound connects various fields of chemistry, such as medicinal chemistry, organic synthesis, and pharmacology, showcasing the intricate links between chemical structure and biological activity.
Overall, the compound exemplifies the crucial relationship between molecular design and biological function, making it a captivating topic for ongoing research and discovery in the world of chemistry. As noted by many scientists, "Understanding the subtle nuances of molecular interactions can usher in a new era of therapeutic breakthroughs."
Synonyms
nefazodone
83366-66-9
Nefazodona
Nefazodonum
Nefazodonum [Latin]
Nefazodona [Spanish]
Nefadar
UNII-59H4FCV1TF
1-(3-(4-(m-Chlorophenyl)-1-piperazinyl)propyl)-3-ethyl-4-(2-phenoxyethyl)-delta2-1,2,4-triazolin-5-one
59H4FCV1TF
Nefazodone (INN)
CHEBI:7494
2-[3-[4-(3-chlorophenyl)piperazin-1-yl]propyl]-5-ethyl-4-(2-phenoxyethyl)-1,2,4-triazol-3-one
CHEMBL623
1-(3-(4-(3-Chlorpheyl-1-piperazinylpropyl)-3-ethyl-4,5-dihydro-4-(2-phenoxyethyl)-1,2,4-triazol-5-on
DTXSID2023357
HSDB 8411
Nefazodonum (Latin)
NEFAZODONE [INN]
Nefazodone [INN:BAN]
1-{3-[4-(3-chlorophenyl)piperazin-1-yl]propyl}-3-ethyl-4-(2-phenoxyethyl)-4,5-dihydro-1H-1,2,4-triazol-5-one
2-{3-[4-(3-chlorophenyl)piperazin-1-yl]propyl}-5-ethyl-4-(2-phenoxyethyl)-2,4-dihydro-3H-1,2,4-triazol-3-one
3H-1,2,4-Triazol-3-one, 2,4-dihydro-2-3-(4-(3-chlorophenyl)-1-piperazinyl)propyl)-5-ethyl-4-(2-phenoxyethyl)-
3H-1,2,4-Triazol-3-one, 2-(3-(4-(3-chlorophenyl)-1-piperazinyl)propyl)-5-ethyl-2,4-dihydro-4-(2-phenoxyethyl)-
3H-1,2,4-TRIAZOL-3-ONE, 2-(3-(4-(3-CHLOROPHENYL)-1-PIPERAZINYL))PROPYL)-5-ETHYL-2,4-DIHYDRO-4-(2-PHENOXYETHYL)-
3H-1,2,4-Triazol-3-one,2-[3-[4-(3-chlorophenyl)-1-piperazinyl]propyl]-5-ethyl-2,4-dihydro-4-(2-phenoxyethyl)-
SMR000550487
NCGC00165846-02
SR-01000759312
2-(3-(4-(3-chlorophenyl)piperazin-1-yl)propyl)-5-ethyl-4-(2-phenoxyethyl)-2,4-dihydro-3H-1,2,4-triazol-3-one
NEFAZODONE [MI]
NEFAZODONE [VANDF]
NEFAZODONE [WHO-DD]
SCHEMBL35089
2-[3-[4-(3-Chlorophenyl)-1-piperazinyl]propyl]-5-ethyl-2,4-dihydro-4-(2-phenoxyethyl)-3H-1,2,4-triazol-3-one
MLS001165769
MLS001195657
BIDD:GT0789
DTXCID203357
GTPL7247
N06AX06
HMS2090D17
HMS2231I17
HMS3264K04
HMS3372C02
Pharmakon1600-01502314
BCP30990
BDBM50069447
NSC760344
AKOS015907198
CCG-213026
DB01149
Dutonin pound>> Nefadar pound>> Serzone
NCGC00165846-01
NCGC00165846-03
2-[3-[4-(3-chlorophenyl)-1-piperazinyl]propyl]-5-ethyl-4-(2-phenoxyethyl)-2H-1,2,4-triazol-3(4H)-one
2-{3-[4-(3-chlorophenyl)piperazin-1-yl]propyl}-5-ethyl-4-[2-(phenyloxy)ethyl]-2,4-dihydro-3H-1,2,4-triazol-3-one
3H-1,2,4-triazol-3-one, 2-(3-(4-(3-chlorophenyl)-1-piperazinyl))propyl-5-ethyl-2,4-dihydro-4-(2-phenoxyethyl)-
AC-37647
HY-119209
CS-0076994
NS00002455
C07256
D08257
AB00640019-14
AB00640019_15
EN300-6733613
L001196
Q416632
SR-01000759312-5
BRD-K90789829-001-07-8
BRD-K90789829-003-03-3
BRD-K90789829-003-12-4
1-(3-(4-(M-CHLOROPHENYL)-1-PIPERAZINYL)PROPYL)-3-ETHYL-4-(2-PHENOXYETHYL)-.DELTA.(SUP 2)-1,2,4-TRIAZOLIN-5-ONE
1-(3-(4-(M-CHLOROPHENYL)-1-PIPERAZINYL)PROPYL)-3-ETHYL-4-(2-PHENOXYETHYL)-delta(SUP 2)-1,2,4-TRIAZOLIN-5-ONE
2-(3-[4-(3-Chlorophenyl)-1-piperazinyl]propyl)-5-ethyl-4-(2-phenoxyethyl)-2,4-dihydro-3H-1,2,4-triazol-3-one #
Solubility of 2-[3-[4-(3-chlorophenyl)piperazin-1-yl]propyl]-5-ethyl-4-(2-phenoxyethyl)-1,2,4-triazol-3-one
The solubility of the compound 2-[3-[4-(3-chlorophenyl)piperazin-1-yl]propyl]-5-ethyl-4-(2-phenoxyethyl)-1,2,4-triazol-3-one (C17H15ClN4O2) can be influenced by its complex structure. Here's a breakdown of important solubility factors:
In conclusion, the solubility of this compound is likely to be a combination of its hydrophilic and hydrophobic properties, meaning it might be soluble in both polar and non-polar solvents, but with varying degrees. The actual solubility must be experimentally determined and could vary under different conditions. Understanding these interactions is key to optimizing its application in various fields.