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Papaverine hydrochloride

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Identification
Molecular formula
C20H21ClNO4
CAS number
61-25-6
IUPAC name
2-[3-(4-chlorophenyl)butyl]-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinolin-2-ium;4-hydroxy-4-oxo-but-2-enoate
State
State

Solid at room temperature.

Melting point (Celsius)
150.50
Melting point (Kelvin)
423.65
Boiling point (Celsius)
311.80
Boiling point (Kelvin)
584.95
General information
Molecular weight
339.82g/mol
Molar mass
339.8230g/mol
Density
1.4500g/cm3
Appearence

White or almost white crystalline powder.

Comment on solubility

Solubility of 2-[3-(4-chlorophenyl)butyl]-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinolin-2-ium;4-hydroxy-4-oxo-but-2-enoate

The solubility of the compound 2-[3-(4-chlorophenyl)butyl]-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinolin-2-ium;4-hydroxy-4-oxo-but-2-enoate can be a fascinating topic due to its complex structure. The solubility of such compounds often depends on several factors including:

  • Polarity: The presence of polar functional groups in the compound may enhance its solubility in polar solvents such as water.
  • Hydrophobic interactions: The aromatic ring and aliphatic chains introduce hydrophobic characteristics that can lead to lower solubility in water.
  • pH dependency: The ionic nature of the quaternary ammonium structure suggests that the solubility may vary with changes in pH.
  • Temperature: Solubility generally increases with temperature; thus, it is essential to consider this factor during solubility testing.

Research often finds that “the solubility of complex organic molecules rarely aligns with simple predictions” due to these influencing factors.

In conclusion, it is crucial to perform empirical tests to definitively determine the solubility of this compound under various conditions, as theoretical predictions alone may not account for all interactions at play.

Interesting facts

Interesting Facts about 2-[3-(4-chlorophenyl)butyl]-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinolin-2-ium; 4-hydroxy-4-oxo-but-2-enoate

The compound 2-[3-(4-chlorophenyl)butyl]-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinolin-2-ium; 4-hydroxy-4-oxo-but-2-enoate represents a fascinating intersection of organic chemistry and pharmacology, integrating complex molecular structures that hint at potential biological activities. Here are some intriguing details:

  • Innovative Structure: This compound features a unique isoquinolinium backbone, which is a class of compounds recognized for their diverse physiological properties. Isoquinolines can act as the central scaffold for various pharmacologically active substances.
  • Chlorophenyl Substituent: The presence of a 4-chlorophenyl group likely influences the compound's lipophilicity and biological activity, making it a key player in drug design where the modification of pharmaceutical properties is crucial.
  • Dimethoxy Groups: The 6,7-dimethoxy substitution pattern may enhance the compound's reactivity and interaction with target biomolecules, suggesting possible pathways for biological exploration.
  • Potential Applications: Given its structural complexity, this compound might exhibit various biological activities such as anti-inflammatory, analgesic, or even anticancer properties. These possibilities make it a candidate for further investigation in medicinal chemistry.
  • Research Opportunities: This compound invites researchers to explore its potential through various synthetic methods and biological assays, focusing on its mode of action and therapeutic Applications.

In summary, compounds like 2-[3-(4-chlorophenyl)butyl]-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinolin-2-ium; 4-hydroxy-4-oxo-but-2-enoate exemplify the beauty and complexity of organic chemistry while holding promise for innovative therapeutic agents. As Albert Einstein once said, "The most beautiful experience we can have is the mysterious," perfectly encapsulating the journey scientists embark on in pursuit of understanding such compounds.